Автор: Antony S. Dimitrov (Ed.) Название: Therapeutic Antibodies ISBN: 1934115924 ISBN-13(EAN): 9781934115923 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Нет в наличии.
Описание: Presents a set of protocols for the discovery and development of therapeutic antibodies, featuring sections focusing on recombinant antigens, antibody libraries, antibody discovery, antibody engineering and antibody preclinical development. This work is suitable for those investigating and participating in this therapeutic market segment.
Автор: Anthony S-Y. Leong Название: Manual of Diagnostic Antibodies for Immunohistology ISBN: 1841101001 ISBN-13(EAN): 9781841101002 Издательство: Cambridge Academ Рейтинг: Цена: 26453.00 р. Наличие на складе: Поставка под заказ.
Описание: The rapid acceptance of immunohistochemistry as an important and even indispensable adjunct to morphological examination and diagnosis requires the modern anatomical pathology laboratory to be conversant with, and proficient in, immunostaining procedures, as well as methods of tissue processing and antigen retrieval and the underlying characteristics of the increasing number of antibodies and antisera available. This fully revised, expanded and updated edition provides a comprehensive list of antisera and monoclonal antibodies that have useful diagnostic applications in tissue sections and cell preparations. Various clones, which are commercially available to detect the same antigen, are listed and the sensitivities and specificities of the antibodies are discussed. Importantly, the authors, all pathologists with a wealth of experience in immunostaining procedures, provide fully referenced details and expert advice on each reagent, with the reader will find invaluable. Finally, the appendices provide easily accessible and clear summaries of selected antibody panels for specific diagnostic situations, details of heat-induced antigen/epitope retrieval (including the use of microwaves) and a useful reference to the websites of the main antibody suppliers.
Автор: Maher Albitar Название: Monoclonal Antibodies ISBN: 1617376469 ISBN-13(EAN): 9781617376467 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting. The chapters offer in-depth description for generating mouse and recombinant humanized antibodies, and a comprehensive review of how antibodies are being used in bead-based methods for measuring proteins.
Автор: Ritter Название: Monoclonal Antibodies ISBN: 0521425034 ISBN-13(EAN): 9780521425032 Издательство: Cambridge Academ Рейтинг: Цена: 14730.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Monoclonal antibodies have a very important and wide-ranging role in many areas of biomedical research and this volume is amongst the very first to combine technical and clinical aspects of the subject.
Автор: G. Subramanian Название: Antibodies ISBN: 1461347017 ISBN-13(EAN): 9781461347019 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
If the antibody industry is to achieve its full potential in the next decade, the individual technical potentials must be exploited, the limitations must be addressed, and lessons learned must be applied both to current purification methods and to the new technologies that continue to emerge. This book presents an overview of the current advances applied in the manufacture of monoclonal antibody including: -concepts in development of manufacturing strategies, -importance of antibody fragments, -application of chromatography method development, -quality control, -effect of expression on antibody properties, -virus removal and safety, -pharmacokinetics, -regulatory aspects.
Antibodies Volume 1: Production and Purification together with Volume2: Novel Technologies and Therapeutic Use will be of great value to all of those who are actively working in the field of antibodies. Volume 2: Novel Technologies and Therapeutic Use brings to the forefront current advances in novel technologies for the manufacturing of monoclonal antibodies and also their extensive clinical importance. Following on from Antibodies Volume 1: Production and Purification, this volume concentrates on: -new technologies in the manufacture of monoclonal antibodies, -the application of antibodies in cancer therapy and functional genomic therapy, -the importance of antibodies and prospects of antibody engineering for the future.
Автор: Ralph A. Reisfeld; Soldano Ferrone Название: Melanoma Antigens and Antibodies ISBN: 1468440810 ISBN-13(EAN): 9781468440812 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: James W. Larrick; C. Borrebaeck Название: Therapeutic Monoclonal Antibodies ISBN: 1349118966 ISBN-13(EAN): 9781349118960 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A review of therapeutic antibodies which have commercial potential. It discusses PCR cloning of Igs, immortalization by gene transfer, scale up production, infectious diseases, viruses, bacteria, parisites, inflammation/immunology, blood grouping, cells, cytokines, tumours and MDR.
Автор: Dirk Saerens; Serge Muyldermans Название: Single Domain Antibodies ISBN: 1493959158 ISBN-13(EAN): 9781493959150 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) book covers single variable domain antibody fragments, which are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost. Includes materials lists, protocols and troubleshooting tips.
Автор: Gunnar Houen Название: Peptide Antibodies ISBN: 1493949993 ISBN-13(EAN): 9781493949991 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For example, peptide antibodies which are dependent on specific posttranslational modifications are of great interest, such as phosphorylation, citrullination and others, while different forms of recombinant peptide antibodies are gaining interest, notably nanobodies, single chain antibodies, TCR-like antibodies, among others.
Автор: Edgar Engleman Название: Human Hybridomas and Monoclonal Antibodies ISBN: 1468449516 ISBN-13(EAN): 9781468449518 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Soon after Kohler and Milstein described the use of somatic cell hybridization for the production of murine monoclonal antibodies of desired specificity, this relatively simple technique became widely applied.
Автор: Lucienne Chatenoud Название: Monoclonal Antibodies in Transplantation ISBN: 3662221977 ISBN-13(EAN): 9783662221976 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection.
Автор: Vincent Ossipow; Nicolas Fischer Название: Monoclonal Antibodies ISBN: 1493963228 ISBN-13(EAN): 9781493963225 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Monoclonal Antibodies: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed modern approaches to isolate and characterize monoclonal antibodies against carefully selected epitopes. This edition includes new chapters covering the key steps to generate high quality monoclonals via different methods, from antigen generation to epitope mapping and quality control of the purified IgG. Chapters are divided into four parts corresponding to four distinct objectives. Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Monoclonal Antibodies: Methods and Protocols, Second Edition provides crucial initial steps of monoclonal antibody generation and characterization with state-of-the art protocols.
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