Peptide Antibodies, Gunnar Houen

Автор: Benjamin Bonavida
Название: Resistance to Immunotherapeutic Antibodies in Cancer
ISBN: 1489987320 ISBN-13(EAN): 9781489987327
Издательство: Springer
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Описание: This book examines antibody-mediated anti-cancer therapy, covering the use of mAbs against various cancers, developments in the molecular, biochemical and genetic mechanisms of resistance by various mAbs and novel mAbs to overcome drug and radition resistance.

Автор: Roland E. Kontermann
Название: Bispecific Antibodies
ISBN: 3642432077 ISBN-13(EAN): 9783642432071
Издательство: Springer
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Цена: 30745.00 р.
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Описание: The concept of using bispecific antibodies for cancer therapy by retargeting immune effector cells was developed several years ago. Initial clinical studies were rather disappointing mainly due to low efficacy, severe side effects and the immunogenicity of the bispecific antibodies. The progress in antibody engineering finally led to the generation of new classes of bispecific antibodies lacking these obstacles. In addition, new applications were established, such as pre-targeting strategies in radioimmunotherapy and dual targeting approaches in order to improve binding, selectivity and efficacy. In this book, the different ways of generating bispecific antibodies are described, with emphasis on recombinant formats. The various applications of bispecific antibodies, e.g. in cellular cancer immunotherapy, radioimmunotherapy and pretargeting strategies are covered, and emerging applications such as dual targeting strategies, which involve the simultaneous inhibition of two targets, are addressed.

Автор: Dirk Saerens; Serge Muyldermans
Название: Single Domain Antibodies
ISBN: 1493959158 ISBN-13(EAN): 9781493959150
Издательство: Springer
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Цена: 21661.00 р.
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Описание: This Methods in Molecular Biology (TM) book covers single variable domain antibody fragments, which are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost. Includes materials lists, protocols and troubleshooting tips.

Автор: Thomas Tiller
Название: Synthetic Antibodies
ISBN: 1493968556 ISBN-13(EAN): 9781493968558
Издательство: Springer
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Описание: This detailed volume presents a set of protocols useful for researchers in the field of recombinant immunoglobulin and alternative scaffold engineering, aptamer development, and generation of molecularly imprinted polymers (MIPs).

Автор: H. Schellekens
Название: Antibodies in Cytokines
ISBN: 0792344073 ISBN-13(EAN): 9780792344070
Издательство: Springer
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Цена: 21661.00 р.
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Описание: Deals with various aspects of cytokine antibodies, from test methodology and standardization to biological consequences and functions. This book encompasses antibodies induced by cytokines used therapeutically and antiviral antibodies. It discusses the effects of cytokine antibodies in experimental animal models and patients.

Автор: Zanetti
Название: The Antibodies
ISBN: 041528466X ISBN-13(EAN): 9780415284660
Издательство: Taylor&Francis
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Описание: From diagnostic tools to therapy against cancer, infections and autoimmune diseases, antibodies serve many purposes, yet our knowledge of them is still incomplete. The Antibodies: Volume 7 continues with a comprehensive review of topics of contemporary interest including major breakthroughs such as the advent of monoclonal antibodies and the develo

Автор: Vincent Ossipow; Nicolas Fischer
Название: Monoclonal Antibodies
ISBN: 1627039910 ISBN-13(EAN): 9781627039918
Издательство: Springer
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Цена: 32142.00 р.
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Описание: Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies.

Автор: Andrew J.T. George; Catherine E. Urch
Название: Diagnostic and Therapeutic Antibodies
ISBN: 1617371955 ISBN-13(EAN): 9781617371950
Издательство: Springer
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Цена: 23058.00 р.
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Описание: Soon after the first description of monoclonal antibodies in 1976, there was enormous interest in the clinical application of antibodies, especially in the context of cancer.

Автор: Hans U. Lutz
Название: Naturally Occurring Antibodies (NAbs)
ISBN: 1493953311 ISBN-13(EAN): 9781493953318
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Here, pioneering researchers report on the tissue homeostatic, tissue regenerating and regulatory properties of NAbs and NAbs in pooled human IgG. The volume also has a chapter on the history of how pooled plasma was pretreated for safe intravenous use.

Автор: James W. Larrick; C. Borrebaeck
Название: Therapeutic Monoclonal Antibodies
ISBN: 1349118966 ISBN-13(EAN): 9781349118960
Издательство: Springer
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Описание: A review of therapeutic antibodies which have commercial potential. It discusses PCR cloning of Igs, immortalization by gene transfer, scale up production, infectious diseases, viruses, bacteria, parisites, inflammation/immunology, blood grouping, cells, cytokines, tumours and MDR.

Автор: Paul Kosma; Sven M?ller-Loennies
Название: Anticarbohydrate Antibodies
ISBN: 3709148359 ISBN-13(EAN): 9783709148358
Издательство: Springer
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Описание: Anticarbohydrate Antibodies provides a cohesive overview of current knowledge on the immunological recognition of carbohydrates by the adaptive immune system. The text provides fundamental insight needed for advancing clinically relevant diagnostics and therapeutic applications.

Автор: Maher Albitar
Название: Monoclonal Antibodies
ISBN: 1617376469 ISBN-13(EAN): 9781617376467
Издательство: Springer
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Описание: This book examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting. The chapters offer in-depth description for generating mouse and recombinant humanized antibodies, and a comprehensive review of how antibodies are being used in bead-based methods for measuring proteins.