Автор: Antony S. Dimitrov (Ed.) Название: Therapeutic Antibodies ISBN: 1934115924 ISBN-13(EAN): 9781934115923 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Поставка под заказ.
Описание: Presents a set of protocols for the discovery and development of therapeutic antibodies, featuring sections focusing on recombinant antigens, antibody libraries, antibody discovery, antibody engineering and antibody preclinical development. This work is suitable for those investigating and participating in this therapeutic market segment.
Автор: John Landon; Tim Chard Название: Therapeutic Antibodies ISBN: 1447119398 ISBN-13(EAN): 9781447119395 Издательство: Springer Рейтинг: Цена: 14365.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Several aspects of clinical medicine are poised on the edge of a new era with the introduction of therapeutic antibodies. This volume is aimed at all clinicians involved with this form of treatment, especially accident and emergency physicians, clinical immunologists, and pharmacologists.
Автор: Michael Steinitz (Editor) Название: Human Monoclonal Antibodies: Methods and Protocols ISBN: 1627035850 ISBN-13(EAN): 9781627035859 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.
Автор: Gunnar Houen Название: Peptide Antibodies ISBN: 1493949993 ISBN-13(EAN): 9781493949991 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For example, peptide antibodies which are dependent on specific posttranslational modifications are of great interest, such as phosphorylation, citrullination and others, while different forms of recombinant peptide antibodies are gaining interest, notably nanobodies, single chain antibodies, TCR-like antibodies, among others.
Автор: Roger H. Kennett Название: Monoclonal Antibodies ISBN: 1461575079 ISBN-13(EAN): 9781461575078 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: On August 7, 1975, Kohler and Milstein published in Nature (256:495) a report describing Continuous cultures of fused cells secreting antibody of predefined specificity. Their report has become a classic and has already had a profound effect on basic and applied research in biology and medicine. By the time the first Workshop on Lymphocyte Hybridomas (Current Topics in Microbiology and Im- munology 81, 1978) was held on April 3-5, 1978, in Bethesda, Maryland, investi- gators from many laboratories had made hybrids between plasmacytomas and spleen cells from immunized animals and had obtained monoclonal antibodies reacting with a broad variety of antigenic determinants. At the time Kohler and Milstein introduced this new technology, the editors of this volume were involved in the production of antisera against differentiation antigens (K. B. B. ), histocompatibility antigens (T. ]. McK. ), and human tumor- associated antigens (R. H. K. ). Because of the potential usefulness of monoclonal antibodies in these areas, we each began production of hybridomas and analysis of the resulting monoclonal reagents. One of the most interesting aspects of participation in the early stages of the development and application of hybrid- oma technology has been observing how the implications of the initial observa- tions gradually spread first among the practitioners of immunology and immu- nogenetics, and then to other areas of the biological sciences, such as developmental biology, biochemistry, human genetics, and cell and tumor biology.
Автор: Ritter Название: Monoclonal Antibodies ISBN: 0521425034 ISBN-13(EAN): 9780521425032 Издательство: Cambridge Academ Рейтинг: Цена: 14730.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Monoclonal antibodies have a very important and wide-ranging role in many areas of biomedical research and this volume is amongst the very first to combine technical and clinical aspects of the subject.
Автор: Juan J. Lafaille; Maria A. Curotto de Lafaille Название: IgE Antibodies: Generation and Function ISBN: 331935888X ISBN-13(EAN): 9783319358888 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites.
Автор: Vincent Ossipow; Nicolas Fischer Название: Monoclonal Antibodies ISBN: 1493963228 ISBN-13(EAN): 9781493963225 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Monoclonal Antibodies: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed modern approaches to isolate and characterize monoclonal antibodies against carefully selected epitopes. This edition includes new chapters covering the key steps to generate high quality monoclonals via different methods, from antigen generation to epitope mapping and quality control of the purified IgG. Chapters are divided into four parts corresponding to four distinct objectives. Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Monoclonal Antibodies: Methods and Protocols, Second Edition provides crucial initial steps of monoclonal antibody generation and characterization with state-of-the art protocols.
Автор: Michael Steinitz Название: Human Monoclonal Antibodies ISBN: 1493960199 ISBN-13(EAN): 9781493960194 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.
Автор: Dirk Saerens; Serge Muyldermans Название: Single Domain Antibodies ISBN: 1493959158 ISBN-13(EAN): 9781493959150 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) book covers single variable domain antibody fragments, which are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost. Includes materials lists, protocols and troubleshooting tips.
Автор: Kresina Название: Monoclonal Antibodies ISBN: 0824781163 ISBN-13(EAN): 9780824781163 Издательство: Taylor&Francis Рейтинг: Цена: 49764.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of
Автор: Zanetti Название: The Antibodies ISBN: 041528466X ISBN-13(EAN): 9780415284660 Издательство: Taylor&Francis Рейтинг: Цена: 32921.00 р. Наличие на складе: Поставка под заказ.
Описание: From diagnostic tools to therapy against cancer, infections and autoimmune diseases, antibodies serve many purposes, yet our knowledge of them is still incomplete. The Antibodies: Volume 7 continues with a comprehensive review of topics of contemporary interest including major breakthroughs such as the advent of monoclonal antibodies and the develo
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