Naturally Occurring Antibodies (NAbs), Hans U. Lutz

Автор: Juan J. Lafaille; Maria A. Curotto de Lafaille
Название: IgE Antibodies: Generation and Function
ISBN: 3319137247 ISBN-13(EAN): 9783319137247
Издательство: Springer
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Описание: This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.

Автор: R?diger Schade; Ingrid Behn; Michael Erhard; Andre
Название: Chicken Egg Yolk Antibodies, Production and Application
ISBN: 3662044900 ISBN-13(EAN): 9783662044902
Издательство: Springer
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Описание: Polyclonal antibodies, widely used in research and diagnostics, are conventionally isolated from the blood of immunised mammals. The fact that antibodies can also be detected in the yolk of eggs laid by immunised hens, led to the development of the yolk antibody technology as an alternative method less stressful to animals.

Автор: Thomas Tiller
Название: Synthetic Antibodies
ISBN: 1493968556 ISBN-13(EAN): 9781493968558
Издательство: Springer
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Описание: This detailed volume presents a set of protocols useful for researchers in the field of recombinant immunoglobulin and alternative scaffold engineering, aptamer development, and generation of molecularly imprinted polymers (MIPs).

Автор: Benjamin Bonavida
Название: Resistance to Immunotherapeutic Antibodies in Cancer
ISBN: 1461476534 ISBN-13(EAN): 9781461476535
Издательство: Springer
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Описание: This book examines antibody-mediated anti-cancer therapy, covering the use of mAbs against various cancers, developments in the molecular, biochemical and genetic mechanisms of resistance by various mAbs and novel mAbs to overcome drug and radition resistance.

Автор: Roger H. Kennett
Название: Monoclonal Antibodies and Functional Cell Lines
ISBN: 1468446754 ISBN-13(EAN): 9781468446753
Издательство: Springer
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Цена: 16979.00 р.
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Описание: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ... . . ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 . . . . . . . . . . . . . . . . . . . . .

Автор: G. Subramanian
Название: Antibodies
ISBN: 1461347025 ISBN-13(EAN): 9781461347026
Издательство: Springer
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Описание: Both the nature of monoclonal antibody therapies and the relatively large size of the monoclonal antibody dictate the production requirements, for many ofthese therapeutics the monoclonal antibody product will be 100 kilogrammes or more per year.

Автор: Edgar Engleman
Название: Human Hybridomas and Monoclonal Antibodies
ISBN: 1468449516 ISBN-13(EAN): 9781468449518
Издательство: Springer
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Описание: Soon after Kohler and Milstein described the use of somatic cell hybridization for the production of murine monoclonal antibodies of desired specificity, this relatively simple technique became widely applied.

Автор: Roger H. Kennett
Название: Monoclonal Antibodies
ISBN: 1461575079 ISBN-13(EAN): 9781461575078
Издательство: Springer
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Описание: On August 7, 1975, Kohler and Milstein published in Nature (256:495) a report describing Continuous cultures of fused cells secreting antibody of predefined specificity. Their report has become a classic and has already had a profound effect on basic and applied research in biology and medicine. By the time the first Workshop on Lymphocyte Hybridomas (Current Topics in Microbiology and Im- munology 81, 1978) was held on April 3-5, 1978, in Bethesda, Maryland, investi- gators from many laboratories had made hybrids between plasmacytomas and spleen cells from immunized animals and had obtained monoclonal antibodies reacting with a broad variety of antigenic determinants. At the time Kohler and Milstein introduced this new technology, the editors of this volume were involved in the production of antisera against differentiation antigens (K. B. B. ), histocompatibility antigens (T. ]. McK. ), and human tumor- associated antigens (R. H. K. ). Because of the potential usefulness of monoclonal antibodies in these areas, we each began production of hybridomas and analysis of the resulting monoclonal reagents. One of the most interesting aspects of participation in the early stages of the development and application of hybrid- oma technology has been observing how the implications of the initial observa- tions gradually spread first among the practitioners of immunology and immu- nogenetics, and then to other areas of the biological sciences, such as developmental biology, biochemistry, human genetics, and cell and tumor biology.

Автор: John Landon; Tim Chard
Название: Therapeutic Antibodies
ISBN: 1447119398 ISBN-13(EAN): 9781447119395
Издательство: Springer
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Описание: Several aspects of clinical medicine are poised on the edge of a new era with the introduction of therapeutic antibodies. This volume is aimed at all clinicians involved with this form of treatment, especially accident and emergency physicians, clinical immunologists, and pharmacologists.

Автор: Chernajovsky
Название: Therapeutic Antibodies
ISBN: 3540732586 ISBN-13(EAN): 9783540732587
Издательство: Springer
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Описание: With contributions by numerous experts

Автор: Suresh C. Srivastava
Название: Radiolabeled Monoclonal Antibodies for Imaging and Therapy
ISBN: 1468455400 ISBN-13(EAN): 9781468455403
Издательство: Springer
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Описание: The advent of hybridoma technology leading to the successful produc- tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations.

Автор: R. Nezlin
Название: Biochemistry of Antibodies
ISBN: 1468417932 ISBN-13(EAN): 9781468417937
Издательство: Springer
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Описание: When the history of immunology in the twentieth century is written, the decade of the 1960`s will, in all probability, stand out as the period of greatest advance in the development of molecular immunology.