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Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins, Ulf Grawunder; Stefan Barth


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Автор: Ulf Grawunder; Stefan Barth
Название:  Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins
ISBN: 9783319468754
Издательство: Springer
Классификация:


ISBN-10: 3319468758
Обложка/Формат: Hardcover
Страницы: 181
Вес: 0.45 кг.
Дата издания: 18.04.2017
Серия: Milestones in Drug Therapy
Язык: English
Издание: 1st ed. 2017
Иллюстрации: 39 illustrations, color; 18 illustrations, black and white; xi, 181 p. 57 illus., 39 illus. in color.
Размер: 234 x 156 x 13
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:

This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities.

The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.




Antibody-Drug Conjugates and Immunotoxins

Автор: Gail Lewis Phillips
Название: Antibody-Drug Conjugates and Immunotoxins
ISBN: 1489997008 ISBN-13(EAN): 9781489997005
Издательство: Springer
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Цена: 22201.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume collets leading research on antibody-drug conjugates and immunotoxins. It examines all aspects of ADCs and ITs from clinical development through to targeted therapeutic applications and the latest technologies.

Antibody-Drug Conjugates

Автор: Ducry
Название: Antibody-Drug Conjugates
ISBN: 1627035400 ISBN-13(EAN): 9781627035408
Издательство: Springer
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Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book presents detailed protocols for key antibody-drug conjugates techniques necessary for working in the field. It provides step-by-step methodologies that are readily reproducible and features expert tips and key implementation advice.

Antibody Methods and Protocols

Автор: Proetzel
Название: Antibody Methods and Protocols
ISBN: 1617799300 ISBN-13(EAN): 9781617799303
Издательство: Springer
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Цена: 20962.00 р.
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Описание: The rapidly growing field of antibody research is the result of many advancing technologies allowing current developments to take advantage of molecular engineering to create tailor-made antibodies.  Antibody Methods and Protocols attempts to provide insight into the generation of antibodies using in vitro and in vivo approaches, as well as technical aspects for screening, analysis, and modification of antibodies and antibody fragments.  The detailed volume is focused on basic protocols for isolating antibodies and, at the same time, it selects a range of specific areas with the aim of providing guides for the overall process of antibody isolation and characterization as well as protocols for enhancing classical antibodies and antibody fragments.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Antibody Methods and Protocols provides a broad and useful background to support ongoing efforts by novices and experts alike and encourages the development of new imaginative approaches to this vital area of study.

Antibody Phage Display

Автор: Robert Aitken (Ed.)
Название: Antibody Phage Display
ISBN: 1603273018 ISBN-13(EAN): 9781603273015
Издательство: Springer
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Цена: 22359.00 р.
Наличие на складе: Поставка под заказ.

Описание: Phage display technology has revolutionized approaches to the analysis of biomedical problems, impacting the fields of immunology, cell biology, biotechnology, pharmacology, and drug discovery. This title provides a resource that guides readers in the design and execution of experiments based around antibody phage display.

Antibody-Drug Conjugates

Автор: Laurent Ducry
Название: Antibody-Drug Conjugates
ISBN: 1493960261 ISBN-13(EAN): 9781493960262
Издательство: Springer
Рейтинг:
Цена: 16769.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book presents detailed protocols for key antibody-drug conjugates techniques necessary for working in the field. It provides step-by-step methodologies that are readily reproducible and features expert tips and key implementation advice.

Resistance to Immunotoxins in Cancer Therapy

Автор: Rama Shanker Verma; Benjamin Bonavida
Название: Resistance to Immunotoxins in Cancer Therapy
ISBN: 3319384562 ISBN-13(EAN): 9783319384566
Издательство: Springer
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Цена: 18284.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book will be a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. As well, it includes an in-depth description of the molecular and cellular mechanisms involved in cancer resistance and several novel methods to overcome resistance.

Clinical Applications of Immunotoxins

Автор: Arthur E. Frankel
Название: Clinical Applications of Immunotoxins
ISBN: 3642721559 ISBN-13(EAN): 9783642721557
Издательство: Springer
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Цена: 18167.00 р.
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Описание: PASTAN , and J. ROBERTUS Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3 Intracellular Processing - Cleavage and Reduction . . . . . . 1 Cytosolic Activity . . . , diphtheria toxin, Pseudomonas exotoxin and ricin) are among the most toxic substances known.

Immunotoxins

Автор: Arthur E. Frankel
Название: Immunotoxins
ISBN: 1461284198 ISBN-13(EAN): 9781461284192
Издательство: Springer
Рейтинг:
Цена: 59955.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up-to-date, easily available on a single library shelf or by a single personal subscription.

Immunotoxins

Автор: Arthur E. Frankel
Название: Immunotoxins
ISBN: 0898389844 ISBN-13(EAN): 9780898389845
Издательство: Springer
Рейтинг:
Цена: 59955.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up-to-date, easily available on a single library shelf or by a single personal subscription.

Resistance to Immunotoxins in Cancer Therapy

Автор: Rama Shanker Verma; Benjamin Bonavida
Название: Resistance to Immunotoxins in Cancer Therapy
ISBN: 3319172743 ISBN-13(EAN): 9783319172743
Издательство: Springer
Рейтинг:
Цена: 19564.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book will be a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted therapy. As well, it includes an in-depth description of the molecular and cellular mechanisms involved in cancer resistance and several novel methods to overcome resistance. Each chapter discusses different aspects of resistance and covers all the factors that may contribute to resistance in cancer cells. Finally, this volume highlights the recent findings and advances associated with tackling cancer resistance.

Molecular and Cellular Mechanisms of Antibody Activity

Автор: Falk Nimmerjahn
Название: Molecular and Cellular Mechanisms of Antibody Activity
ISBN: 1489993606 ISBN-13(EAN): 9781489993601
Издательство: Springer
Рейтинг:
Цена: 22201.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Recent years have seen an exponential growth in knowledge about the molecular and cellular mechanisms of antibody activity. This book examines how these new results have dramatically changed our view of how antibodies function in vivo.

Antibody Engineering Volume 2

Автор: Roland E. Kontermann; Stefan D?bel
Название: Antibody Engineering Volume 2
ISBN: 3642422764 ISBN-13(EAN): 9783642422768
Издательство: Springer
Рейтинг:
Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new techniques. The protocols reflect the latest "hands on" knowledge of key laboratories in this still fast-moving field. Newcomers will benefit from the proven step-by-step protocols, which include helpful practical advice; experienced antibody engineers will appreciate the new ideas and approaches. The book is an invaluable resource for all those engaged in antibody research and development.


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