Immunotoxins, Arthur E. Frankel

Автор: Arthur E. Frankel
Название: Clinical Applications of Immunotoxins
ISBN: 3642721559 ISBN-13(EAN): 9783642721557
Издательство: Springer
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Цена: 18167.00 р.
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Описание: PASTAN , and J. ROBERTUS Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3 Intracellular Processing - Cleavage and Reduction . . . . . . 1 Cytosolic Activity . . . , diphtheria toxin, Pseudomonas exotoxin and ricin) are among the most toxic substances known.

Автор: Ulf Grawunder; Stefan Barth
Название: Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins
ISBN: 3319468758 ISBN-13(EAN): 9783319468754
Издательство: Springer
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Цена: 20962.00 р.
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Описание:

This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities.

The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.

Автор: Arthur E. Frankel
Название: Immunotoxins
ISBN: 0898389844 ISBN-13(EAN): 9780898389845
Издательство: Springer
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Цена: 59955.00 р.
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Описание: It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up-to-date, easily available on a single library shelf or by a single personal subscription.

Автор: Rama Shanker Verma; Benjamin Bonavida
Название: Resistance to Immunotoxins in Cancer Therapy
ISBN: 3319172743 ISBN-13(EAN): 9783319172743
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This book will be a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted therapy. As well, it includes an in-depth description of the molecular and cellular mechanisms involved in cancer resistance and several novel methods to overcome resistance. Each chapter discusses different aspects of resistance and covers all the factors that may contribute to resistance in cancer cells. Finally, this volume highlights the recent findings and advances associated with tackling cancer resistance.

Автор: Rama Shanker Verma; Benjamin Bonavida
Название: Resistance to Immunotoxins in Cancer Therapy
ISBN: 3319384562 ISBN-13(EAN): 9783319384566
Издательство: Springer
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Цена: 18284.00 р.
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Описание: This book will be a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. As well, it includes an in-depth description of the molecular and cellular mechanisms involved in cancer resistance and several novel methods to overcome resistance.

Автор: Gail Lewis Phillips
Название: Antibody-Drug Conjugates and Immunotoxins
ISBN: 1489997008 ISBN-13(EAN): 9781489997005
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This volume collets leading research on antibody-drug conjugates and immunotoxins. It examines all aspects of ADCs and ITs from clinical development through to targeted therapeutic applications and the latest technologies.