Activation and Detoxification Enzymes, Chang-Hwei Chen
Автор: Stenmark Harald Название: Phosphoinositides in Subcellular Targeting and Enzyme Activation ISBN: 3540009507 ISBN-13(EAN): 9783540009504 Издательство: Springer Рейтинг: Цена: 1092.00 р. Наличие на складе: Есть (3 шт.) Описание: Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.
Автор: Arthur Martell Название: Oxygen Complexes and Oxygen Activation by Transition Metals ISBN: 1461282632 ISBN-13(EAN): 9781461282631 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This monograph consists of manuscripts, summary statements, and poster abstracts submitted by invited speakers and poster contributors who participated in the symposium "Oxygen Complexes and Oxygen Activation by Transition Metals," held March 23-26, 1987, at Texas A&M University.
Автор: Stephen W. Russell; Siamon Gordon Название: Macrophage Biology and Activation ISBN: 3642773796 ISBN-13(EAN): 9783642773792 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aspects covered in this volume have been selected to provide an overview of subject areas that either have recently become much better understood or hold the promise of new levels of understanding as they are developed in the future.
Описание: A role for vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions, encompassing embryogenesis, postnatal development to old age. A wealth of intercellular interactions, intracellular signaling systems and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for life. This book series, with chapters authored by experts in every aspect of this complex field, unifies the knowledge base and mechanisms currently known in detailed, engaging, well-illustrated, focused chapters that synthesize information for each specific area. In view of the recent explosion in this field, it is timely to publish a contemporary, comprehensive, book series recapitulating the most exciting developments in the field and covering fundamental research in molecular mechanisms of vitamin A action, its role in physiology, development and continued well-being and the potential of vitamin A derivatives and synthetic mimetics to serve as therapeutic treatments for cancers and other debilitating human diseases. VOLUME I: Here, we present the first volume of a multi-volume series on Retinoic Acid Signaling that will cover all aspects of this broad and diverse field. One aim of Volume I is to present a compilation of topics related to the biochemistry of nuclear retinoic acid receptors, from their architecture when bound to DNA and associated with their coregulators to their ability to regulate target gene transcription. A second aim is to provide insight into recent advances that have been made in identifying novel targets and non-genomic effects of retinoic acid. Volume I is divided into ten chapters contributed by prominent experts in their respective fields. Each chapter starts with the history of the area of research. Then, the key findings that contributed to development of the field are described, followed by a detailed look at key findings and progress that are being made in current, ongoing research. Each chapter is concluded with a discussion of the relevance of the research and a perspective on missing pieces and lingering gaps that the author recommends will be important in defining future directions in vitamin A research.
Автор: Michael N. Alexis; Constantin E. Sekeris Название: Activation of Hormone and Growth Factor Receptors ISBN: 9401073643 ISBN-13(EAN): 9789401073646 Издательство: Springer Рейтинг: Цена: 36756.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop, Nafplion, Greece, September 25-30, 1988
Описание: This book investigates the function and mechanism of a newly discovered heme-thiolate peroxygenase, AaeAPO. Featuring clear illustrations with original research data, it demonstrates that the peroxygenase catalyzes a wide range of reactions.
Forward, Mary Ann Asson-Batres and Cecile Rochette-Egly
1 History of Retinoic Acid Receptors Doris M. Benbrook, Pierre Chambon, Cecile Rochette-Egly, and Mary Ann Asson-Batres 2 Architecture of DNA Bound RAR Heterodimers Natacha Rochel and Dino Moras 3 Retinoic Acid Receptors: Structural Basis for Coregulator Interaction and Exchange Albane le Maire and William Bourguet 4 Evolution of Retinoic Acid Receptors and Retinoic Acid Signaling Juliana Gutierrez-Mazariegos, Michael Schubert and Vincent Laudet 5 RXRs: Collegial Partners Federica Gilardi and Bйatrice Desvergne 6 Nuclear and Extra-Nuclear Effects of Retinoic Acid Receptors: How they are interconnected Aleksandr Piskunov, Ziad Al Tanoury, and Cйcile Rochette-Egly 7 The Roles of Retinoic Acid and Retinoic Acid Receptors in Inducing Epigenetic Changes Alison Urvalek, Kristian Laursen, and Lorraine J. Gudas 8 RARs and microRNAs Clara Nervi and Francesco Grignani 9 Integrative genomics to dissect retinoids functions Marco-Antonio Mendoza-Parra and Hinrich Gronemeyer 10 Complexity of the RAR‐Mediated Transcriptional Regulatory Programs Zhijie Liu, Qidong Hu and Michael G. Rosenfeld Index.
Описание: The subject of dioxygen activation and homogeneous catalytic oxidation by metal complexes has been in the focus of attention over the last 20 years.
Автор: T.M. Konijn; M.D. Houslay; P.J.M. van Haastert Название: Activation and Desensitization of Transducing Pathways ISBN: 3642836208 ISBN-13(EAN): 9783642836206 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Activation and Desensitization of Transducing Pathways held at Noordwijkerhout, The Netherlands, May 25-27, 1989
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