The Retinal M?ller Cell, Vijay Sarthy; Harris Ripps

Автор: Catherine Bowes Rickman; Matthew M. LaVail; Robert
Название: Retinal Degenerative Diseases
ISBN: 3319371525 ISBN-13(EAN): 9783319371528
Издательство: Springer
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Описание:

Part I Age-Related Macular Degeneration (AMD).- Apolipoprotein E Isoforms and AMD.- Role of Chemokines in Shaping Macrophage Activity in AMD.- Biology of p62/sequestosome-1 in Age-Related Macular Degeneration (AMD).- Gene Structure of the 10q26 locus: A Clue to Cracking the ARMS2/HTRA1 Riddle?.- Conditional Induction of Oxidative Stress in RPE: A Mouse Model of Progressive Retinal Degeneration.- Therapeutic Approaches to Histone Reprogramming in Retinal Degeneration.- A Brief Discussion on Lipid Activated Nuclear Receptors and Their Potential Role in Regulating Microglia in Age-Related Macular Degeneration (AMD).- Extracellular Matrix Alterations and Deposit Formation in AMD.- The NLRP3 Inflammasome and its Role in Age-related Macular Degeneration.- Oxidative Stress and the Nrf2 Anti-Oxidant Transcription Factor in Age-Related Macular Degeneration.- Aging Changes in Retinal Microglia and their Relevance to Age-related Retinal Disease.- VEGF-A and the NLRP3 Inflammasome in Age-Related Macular Degeneration.- Interrelation Between Oxidative Stress and Complement Activation in Models of Age-Related Macular Degeneration.- Gene-diet Interactions in Age-Related Macular Degeneration.- Challenges in the Development of Therapy for Dry Age-Related Macular Degeneration.- Nanoceria: A Potential Therapeutic for Dry AMD.- β-amyloidopathy in the Pathogenesis of Age-Related Macular Degeneration in Correlation with Neurodegenerative Diseases.- Part II Macular Dystrophies/Inherited Macular Degeneration.- Different Mutations in ELOVL4 Affect Very Long Chain Fatty Acid Biosynthesis to Cause Variable Neurological Disorders in Humans.- Mouse Models of Stargardt 3 Dominant Macular Degeneration.- Current Progress in Deciphering Importance of VLC-PUFA in the Retina.- Malattia Leventinese/Doyne Honeycomb Retinal Dystrophy: Similarities to Age-related Macular Degeneration and Potential Therapies.- Part III Inherited Retinal Degenerations.- Hsp90 as a Potential Therapeutic Target in Retinal Disease.- Leber Congenital Amaurosis: Genotypes and Retinal Structure Phenotypes.- A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects.- Ablation of Chop Transiently Enhances Photoreceptor Survival But Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin.- Identification of a Novel Gene on 10q22 Causing Autosomal Dominant Retinitis Pigmentosa (adRP).- FAM161A and TTC8 Are Differentially Expressed in Non-allelelic Early Onset Retinal Degeneration.- Mutations in the Dynein1 Complex are Permissible for Basal Body Migration in Photoreceptors but Alter Rab6 Localization.- RDS Functional Domains and Dysfunction in Disease.- TULP1 Missense Mutations Induces the Endoplasmic Reticulum Unfolded Protein Response Stress Complex (ER-UPR).- Understanding Cone Photoreceptor Cell Death in Achromatopsia.- Geranylgeranylacetone Suppresses N-methyl-N-nitrosourea-induced Photoreceptor Cell Loss in Mice.- My Retina Tracker(TM) An On-line International Registry for People Affected with Inherited Orphan Retinal Degenerative Diseases and their Genetic Relatives - A New Resource.- A Mini-Review: Animal Models of GUCY2D Leber Congenital Amaurosis (LCA1).- A Comprehensive Review of Mutations in the MERTK Proto-oncogene.- Part IV In Vivo Imaging and Other Diagnostic Advances.- New Developments in Murine Imaging for Assessing Photoreceptor Degeneration In Vivo.- Reliability and repeatability of Cone Density Measurements in Patients with Congenital Achromatopsia.- Quantitative Autofluorescence in Best Vitelliform Macular Dystrophy: RPE Lipofuscin is Not Increased in Non-Lesion Areas of Retina.- Interpretation of Flood-Illuminated Adaptive Optics Images in Subjects with Retinitis Pigmentosa.- Intra-familial Similarity of Wide-Field Fundus Autofluorescence in Inherited
Retinal Dystrophy.- Wide-Field Fundus Autofluorescence for Retinitis Pigmentosa

Автор: Joe G. Hollyfield; Robert E. Anderson; Matthew M L
Название: Retinal Degenerative Diseases
ISBN: 1489997725 ISBN-13(EAN): 9781489997722
Издательство: Springer
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Описание: Retinal Degenerations is the result of the International Symposium on Retinal degeneration which has become perhaps the most important research meeting in the field. THe topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration.

Автор: Matthew M. LaVail; Joe G. Hollyfield; Robert E. An
Название: Retinal Degenerations
ISBN: 1461349095 ISBN-13(EAN): 9781461349099
Издательство: Springer
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Автор: Vijay Sarthy; Harris Ripps
Название: The Retinal M?ller Cell
ISBN: 0306464705 ISBN-13(EAN): 9780306464706
Издательство: Springer
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Описание: Examines the role of the Muller cell, the main glial element of the retina, in the development, organization, and function of the vertebrate retina. These cells may also play a role in the control of eye growth and in determining the processing of information by surrounding neurons.

Автор: Joyce Tombran-Tink; Colin J. Barnstable
Название: Retinal Degenerations
ISBN: 1493960989 ISBN-13(EAN): 9781493960989
Издательство: Springer
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Цена: 34937.00 р.
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Описание: For centuries, humans have tried to explain the complex process of vision and find effective treatments for eye diseases. Perhaps the oldest surviving record of ancient ophthalmic practices is the Babylonian code of Hammurabi that over 4000 years ago, mentioned fees for eye surgery—and penalties for unsuccessful operations that led to loss of the eye. Babylonian medicine was controlled by priests who directed the work of skilled surgeons. The earliest records of Egyptian medicine date from almost the same time. The Ebers Papyrus, dating back to more than 3500 years ago is a superbly preserved document in which a section outlines a relatively advanced system of diagnosis and treatment of various ocular pathologies. The text reveals that ancient Greek and Egyptian physicians prescribed “liver juice” for night blindness. This was obtained from roasted and crushed ox liver. We now know that their prescription contained a remarkable amount of vitamin A. It was only within the last century, however, that we have recognized the importance of vitamin A to the function of photoreceptors and visual acuity and that its deficiency can result in night blindness. Egyptian ophthalmological practices were held in high esteem in the ancient world and so were their medical institutes, called “peri-ankh,” which existed since the first dynasty. Herodotus, the fifth century BC Greek historian, comments on the specialization of the physicians: “Each physician treats just one disease.

Автор: John D. Ash; Christian Grimm; Joe G. Hollyfield; R
Название: Retinal Degenerative Diseases
ISBN: 1493952765 ISBN-13(EAN): 9781493952762
Издательство: Springer
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Автор: Nakazawa
Название: Neuroprotection and Neuroregeneration for Retinal Diseases
ISBN: 4431549641 ISBN-13(EAN): 9784431549642
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book provides the latest findings on neuroprotection and neuroregeneration as potential therapeutic strategies for various eye diseases, namely, glaucoma, age-related macular degeneration (AMD), retinal detachment, and retinitis pigmentosa.

Автор: A.M. Joussen; T.W. Gardner; B. Kirchhof; S.J. Ryan
Название: Retinal Vascular Disease
ISBN: 3662500302 ISBN-13(EAN): 9783662500309
Издательство: Springer
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Цена: 24456.00 р.
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Описание: Vascular diseases of the retina are a major cause of blindness among all age groups. Edited and written by internationally well-known experts, this state-of-the-art comprehensive overview of basic and clinical science will enhance the understanding of retinal vascular disease and help in the evaluation of current and future treatment approaches for the clinician. The well-structured and highly illustrated text is divided into the following three main sections: Pathogenesis of retinal vascular disease General concepts in the diagnosis and treatment of retinal vascular disease Pathology, clinical course and treatment of retinal vascular disease Reader-friendly through: Step-by-step explanation of all treatment procedures Richly illustrated by clinical image series including illustrated single case follow-up This unique textbook-atlas also includes topics which are not currently found in other retinal disease textbooks, such as case reports and clinical follow-ups. General ophthalmologists, retina specialists as well as ophthalmologists in training will find this book highly stimulating and useful for their daily practice.

Автор: Robert E. Anderson; Matthew M. LaVail; Joe G. Holl
Название: New Insights Into Retinal Degenerative Diseases
ISBN: 1461355133 ISBN-13(EAN): 9781461355137
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Since 1984, we have organized satellite symposia on retinal degenerations that are held in conjunction with the biennial International Congress of Eye Research. The timing and location of our Retinal Degeneration Symposia have allowed scientists and clinicians from around the world to convene and present their exciting new findings.

Автор: Siegfried Hoyer; Dorothea M?ller; Konstanze Plasch
Название: Cell and Animal Models in Aging and Dementia Research
ISBN: 3211825495 ISBN-13(EAN): 9783211825495
Издательство: Springer
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Цена: 12157.00 р.
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Описание: In this supplement, different approaches are dealt with how to induce structural and/or metabolic abnormalities in relevant cell cultures, in brain slices and in experimental animals, and how behavioral changes parallel the metabolic variations.