Cell and Animal Models in Aging and Dementia Research, Siegfried Hoyer; Dorothea M?ller; Konstanze Plasch

Автор: Peter Paul De Deyn; Debby Van Dam
Название: Animal Models of Dementia
ISBN: 1493961187 ISBN-13(EAN): 9781493961184
Издательство: Springer
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Цена: 25155.00 р.
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Описание: With an ever-increasing elderly population and the resultant rising levels of dementia-related disorders, preclinical research based on animal models is pivotal to our knowledge of underlying molecular mechanisms and drug discovery aiming at the development of therapeutic strategies alleviating or preventing the neurological devastation. In Animal Models of Dementia, expert researchers provide contributions that stress the importance of extensively validated animal models in drug discovery and development in order to predict clinical activity. Beginning with general aspects of animal modeling, related ethical issues, and essential methodological considerations, the highly detailed volume then continues with various levels of model validation, including pathological, behavioral, neurochemical, pharmacological, and imaging aspects, followed by sections focused on specific disorders, such as Alzheimer’s disease, Parkinson’s disease, metachromatic leukodystrophy and adrenoleukodystrophy, amyotrophic lateral sclerosis, frontotemporal dementia as well as vascular dementia and more. As a volume in the renowned Neuromethods series, this book offers a detailed, yet accessible, overview of currently available animal models in the field of dementia research, and touches, as well, upon more general areas linked to the development and use of animal models. Comprehensive and efficient, Animal Models of Dementia will significantly aid both experienced animal researchers as well as investigators on the verge of beginning animal model-based dementia research.

Автор: Downs, Murna Bowers, Barbara
Название: Excellence in Dementia Care: Research into Practice
ISBN: 0335245331 ISBN-13(EAN): 9780335245338
Издательство: McGraw-Hill
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Цена: 7034.00 р.
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Описание: A comprehensive text on dementia care, drawn from research evidence, practice and the experience of people with dementia.

Автор: Alain O.A. Miller
Название: Advanced Research on Animal Cell Technology
ISBN: 940106881X ISBN-13(EAN): 9789401068819
Издательство: Springer
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Цена: 12157.00 р.
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Описание: Proceedings of the NATO Advanced Research Workshop, Brussels, Belgium, September 21-24, 1987

Автор: August Bernd; J?rgen Bereiter-Hahn; Frank Hevert;
Название: Cell and Tissue Culture Models in Dermatological Research
ISBN: 3642778194 ISBN-13(EAN): 9783642778193
Издательство: Springer
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Цена: 15372.00 р.
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Описание: In this volume the impact of cell culture models ondermatological research is discussed by scientists frommedicine, physiology, biology, pharmacology,and pharmacy.

Автор: Jennifer L. Bizon; Alisa G. Woods
Название: Animal Models of Human Cognitive Aging
ISBN: 1627038035 ISBN-13(EAN): 9781627038034
Издательство: Springer
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Цена: 26120.00 р.
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Описание: In this groundbreaking book, a panel of international authorities discusses the use of animal models as a tool for understanding cognitive changes associated with the aging process. The book provides a valuable resource for all aging medicine researchers.

Автор: Kurt A. Jellinger; Reinhold Schmidt; Manfred Windi
Название: Advances in Dementia Research
ISBN: 3211835121 ISBN-13(EAN): 9783211835128
Издательство: Springer
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Цена: 22359.00 р.
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Описание: Dementia is a major health problem that becomes increasingly common with advancing age. Thus, this volume provides a timely overview of most recent developments in dementia research and treatment strategies of dementia disorders.

Автор: T. Zollner; Harald Renz; Khusru Asadullah
Название: Animal Models of T Cell-Mediated Skin Diseases
ISBN: 3642422055 ISBN-13(EAN): 9783642422058
Издательство: Springer
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Цена: 22201.00 р.
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Описание: Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character.

Автор: Bruno Christ; Jana Oerlecke; Peggy Stock
Название: Animal Models for Stem Cell Therapy
ISBN: 149394813X ISBN-13(EAN): 9781493948130
Издательство: Springer
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Цена: 16769.00 р.
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Описание: In Animal Models for Stem Cell Therapy: Methods and Protocols, expert researchers in the field detail disease models of hepatic, cardiovascular, neurological diseases, connective and contractile tissue. Chapters focus on a wide range of diseases and application of different kinds of stem cells and reprogrammed tissue cells (iPS). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Animal Models for Stem Cell Therapy: Methods and Protocols, covers interest of basic scientists and clinicians to assess the biological as well as the therapeutic potential of stem cell therapy.

Автор: Mary T. Phillips; Jeri A. Sechzer
Название: Animal Research and Ethical Conflict
ISBN: 1461281814 ISBN-13(EAN): 9781461281818
Издательство: Springer
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Цена: 14673.00 р.
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Описание: The original purpose of the survey was to provide packground information for the development of a set of guide- lines for the use of animals in research then in preparation by The New York Academy of Sciences` Ad Hoc Committee on Animal Research.