Animal Models for Stem Cell Therapy, Bruno Christ; Jana Oerlecke; Peggy Stock

Автор: Siegfried Hoyer; Dorothea M?ller; Konstanze Plasch
Название: Cell and Animal Models in Aging and Dementia Research
ISBN: 3211825495 ISBN-13(EAN): 9783211825495
Издательство: Springer
Рейтинг:
Цена: 12157.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In this supplement, different approaches are dealt with how to induce structural and/or metabolic abnormalities in relevant cell cultures, in brain slices and in experimental animals, and how behavioral changes parallel the metabolic variations.

Автор: Boelens Jaap Jan
Название: Stem Cell Therapy in Lysosomal Storage Diseases
ISBN: 1461483565 ISBN-13(EAN): 9781461483564
Издательство: Springer
Рейтинг:
Цена: 23508.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume discusses the history, current practice and future perspectives of stem cell in inborn errors of metabolism and provides an international perspective on progress, limitations, and future directions in the field.

Автор: Indumathi Somasundaram
Название: Stem Cell Therapy for Organ Failure
ISBN: 8132221095 ISBN-13(EAN): 9788132221098
Издательство: Springer
Рейтинг:
Цена: 22359.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The book “STEM CELL THERAPY FOR ORGAN FAILURES” edited by Dr. S. Indumathi demonstrates the In Vitro and In vivo therapeutic strategies and applications of pre- and post-natal stem cells for treating the failures of various organ systems of our body in a wide perspective. It explores the past, present and the futuristic approach of the exciting field of stem cells and its intriguing properties involved in tissue repair and regeneration. The prime focus of this volume is to unravel the basic, advanced, therapeutic and translational approaches put-forth so far in the field of stem cells and regenerative medicine at research, pre-clinical and clinical levels. Stem cells has ushered in widespread interest and exciting possibilities for cell based therapies, albeit failures do prevail and small uncontrolled phase I/II studies are only signals generating, rather than definite proof of concept thereby limiting its applicability in curative therapeutics. Despite certain initiatives and meticulous untiring efforts, bringing this basic bench side research into advanced transitional bedside remained a challenge. Thus, this book embarked upon the expanding researches in these areas that seem decisive in improvising regenerative medical therapeutics, thereby leading to further path-breaking studies that cure all health challenges facing mankind. Overall, this book reveals the imperativeness of various stem cell sources and its utility in curative therapeutics.

Автор: Robert Lanza
Название: Essentials of Stem Cell Biology,
ISBN: 0124095038 ISBN-13(EAN): 9780124095038
Издательство: Elsevier Science
Рейтинг:
Цена: 26444.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Suitable for scientists, researchers, practitioners, and students embracing the advances in stem cells, this book covers basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, and methods to the application of stem cells to specific human diseases, regulation and ethics, and patient perspectives.

Автор: T. Zollner; Harald Renz; Khusru Asadullah
Название: Animal Models of T Cell-Mediated Skin Diseases
ISBN: 3642422055 ISBN-13(EAN): 9783642422058
Издательство: Springer
Рейтинг:
Цена: 22201.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character.

Автор: Shimon Efrat
Название: Stem Cell Therapy for Diabetes
ISBN: 1617796697 ISBN-13(EAN): 9781617796692
Издательство: Springer
Рейтинг:
Цена: 32004.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming.

Автор: El-Badri
Название: Advances in Stem Cell Therapy
ISBN: 3319291475 ISBN-13(EAN): 9783319291475
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The book reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals. This is followed by exhaustive review of clinical trials in these pathologies. It continues with a comparison of the merits of successful transplantation in humans versus animal experimentation, and highlights the most promising clinical applications in the field. Special chapters are devoted to the topic of tissue engineering and modern synthetic and biological scaffolds. It is essential reading for scientists and researchers in tissue engineering and stem cell research as well as clinicians who are involved in developing or testing stem cell therapies.

Автор: Tarun Pandey
Название: Imaging in Stem Cell Transplant and Cell-based Therapy
ISBN: 3319518313 ISBN-13(EAN): 9783319518312
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book provides a review of imaging techniques and applications in stem cell transplantation and other cell-based therapies. Essential reading for radiologists and physicians who are interested in developing a basic understanding of stem cell imaging and applications of stem cells and cell based therapies.

Автор: Lucas G. Chase; Mohan C Vemuri
Название: Mesenchymal Stem Cell Therapy
ISBN: 1627039147 ISBN-13(EAN): 9781627039147
Издательство: Springer
Рейтинг:
Цена: 21661.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Автор: Mohamed Al-Rubeai; Mariam Naciri
Название: Stem Cells and Cell Therapy
ISBN: 9402402187 ISBN-13(EAN): 9789402402186
Издательство: Springer
Рейтинг:
Цена: 16977.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products.

Автор: Mohamed Al-Rubeai; Mariam Naciri
Название: Stem Cells and Cell Therapy
ISBN: 9400771959 ISBN-13(EAN): 9789400771956
Издательство: Springer
Рейтинг:
Цена: 19591.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products.

Автор: Nicole I. Nieden
Название: Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases
ISBN: 1493957236 ISBN-13(EAN): 9781493957231
Издательство: Springer
Рейтинг:
Цена: 20263.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In this dependable and cutting-edge book, accomplished investigators provide detailed descriptions on how to expand ESCs from the most commonly used species ex vivo, i.e. mouse and human, in static culture as well as in controllable bioreactor processes.