Автор: Randall J. Mrsny, Ann Daugherty Название: Proteins and Peptides: Pharmacokinetic, Pharmacodynamic, and Metabolic Outcomes ISBN: 1420078062 ISBN-13(EAN): 9781420078060 Издательство: Taylor&Francis Рейтинг: Цена: 19293.00 р. 27562.00-30% Наличие на складе: Есть (1 шт.) Описание: Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate. Proteins and Peptides is an invaluable source for drug discovery and development scientists in the biopharmaceutical industry who frequently navigate the maze of protein and peptide pharmacokinetics, pharmacodynamics, and metabolism.
Key features include:
issues related to delivery of protein and peptide therapeutics in elderly populations and pharmacogenomics
lessons learned on the major marketed areas of proteins and peptides, including interleukins, interferons, growth factors, and peptide hormones
innovations for protein and peptide delivery such as needle-less delivery
strategies for delivery of these molecules to locations such as the eye and brain
generic issues of proteins and peptides
Автор: Dietmar Richter Название: Regulatory Peptides and Cognate Receptors ISBN: 3540653252 ISBN-13(EAN): 9783540653257 Издательство: Springer Рейтинг: Цена: 44582.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since the 1980s, our knowledge of regulatory peptides and their cognate receptors has greatly increased. This text discusses various peptide receptor systems, for example CRF, somatostatin, TRH, opioid peptides and vasopressin, and strategies for uncovering new peptides are examined.
Автор: Marie-Isabel Aguilar Название: HPLC of Peptides and Proteins ISBN: 1617372862 ISBN-13(EAN): 9781617372865 Издательство: Springer Рейтинг: Цена: 24456.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The introduction of high-performance liquid chromatography (HPLC) to the analysis of peptides and proteins some 25 years ago revolutionized the biological sciences by enabling the rapid and sensitive analysis of peptide and protein structure through the exquisite speed, sensitivity, and resolution that can be easily obtained.
Автор: Andrea Giuliani; Andrea C. Rinaldi Название: Antimicrobial Peptides ISBN: 1607615932 ISBN-13(EAN): 9781607615934 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, leading investigators present a broad, up-to-date collection of current research and experimental methods for the isolation, characterization, production, and optimization of AMPs. The book covers a rapidly expanding field of research.
Автор: Mark A. Strege; Avinash L. Lagu Название: Capillary Electrophoresis of Proteins and Peptides ISBN: 1617373079 ISBN-13(EAN): 9781617373077 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Throughout the more than 20 years that have followed the beginnings of capillary electrophoresis (CE), its application to the analysis of proteins and peptides has continued to be reliable, versatile, and productive.
Автор: Ralph W. Jack; Gabriele Bierbaum; Hans-Georg Sahl Название: Lantibiotics and Related Peptides ISBN: 3540636005 ISBN-13(EAN): 9783540636007 Издательство: Springer Рейтинг: Цена: 29209.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: J.M. Polak Название: Regulatory Peptides ISBN: 3764319763 ISBN-13(EAN): 9783764319762 Издательство: Springer Рейтинг: Цена: 11173.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Alan A. Boulton; Glen B. Baker; Q. J. Pittman Название: Peptides ISBN: 0896031055 ISBN-13(EAN): 9780896031050 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: K.O. Stumpe; Karin Kraft; Alan I. Faden Название: Opioid Peptides and Blood Pressure Control ISBN: 3540189351 ISBN-13(EAN): 9783540189350 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A. , FADEN, K. KRAFr, and K. O. STUMPE Following the discovery of the pentapeptide enkephalins in 1975, a number of endogenous opioid peptides and opiate receptors have been identified. Endogenous opioids and opiate-receptor mechanisms have been implicated in a variety of regulat- ory and dysregulatory functions including analgesia, cardiovascular regulation, shock, hypertension, traumatic spinal cord and brain injury, stroke, immune func- tion, feeding behavior, diuresis, gastrointestinal motility, and respiratory control, among others. Over the past 10 years, many studies have demonstrated a relationship between endogenous opioids and the cardiovascular system under both homeostatic and pathophysiological conditions. Opioids and opiate receptors have been found in various cardioregulatory sites within the brain and spinal cord, as well as in peripheral tissues such as sympathetic ganglia, adrenal gland, and heart. Both endogenous opioids and exogenous opiates have been shown to produce potent cardiovascular effects following central nervous system or systemic administration. Opiate-receptor antagonists have been demonstrated to reverse hypotension from sepsis, hypo- volemia, and anaphylaxis; such studies have been used to infer activity of endogenous opioid systems in shock. Changes in tissue concentrations of endogenous opioids and or opiate receptors have been found after shock and hypertension, further implying a role for opioid systems in the etiology of these conditions. In addition, modification of opiate receptor regulation, receptor binding, or opioid metabolism has also been used to establish a potential role for endogenous opioid systems in cardiovascular control and dyscontrol.
Автор: James A. Ferrendelli; Robert C. Collins; Eugene M. Название: Neurobiology of Amino Acids, Peptides and Trophic Factors ISBN: 0898383609 ISBN-13(EAN): 9780898383607 Издательство: Springer Рейтинг: Цена: 33401.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Third Annual International Symposium on Neuronal Control of Bodily Function: Basic and Clinical Aspects - November 4-7, 1986
Автор: John Hughes Название: Centrally Acting Peptides ISBN: 1349036706 ISBN-13(EAN): 9781349036707 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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