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Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future, Silvia Mandel


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Автор: Silvia Mandel
Название:  Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future
ISBN: 9789400792951
Издательство: Springer
Классификация:





ISBN-10: 9400792956
Обложка/Формат: Paperback
Страницы: 398
Вес: 0.58 кг.
Дата издания: 08.02.2015
Серия: Advances in Predictive, Preventive and Personalised Medicine
Язык: English
Размер: 234 x 156 x 22
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:

Part I

1. What is this book series about? Foreword of Book Series Editor; O. Golubnitschaja

2. Preface; S. Mandel

3. Introductory chapter; S. Mandel and O. Golubnitschaja

Part II

4. Individual predispositions in healthy vasospastic individuals: Patient profiling for targeted prevention of down-stream pathologies as cost-effective personalised medicine; K. Yeghiazaryan, J. Flammer, O. Golubnitschaja

5. Idiopathic REM sleep behavior disorder as a long-term predictor of neurodegenerative disorders; S. Fulda and M. Manconi

6. New animal models of progressive neurodegeneration: tools for developing predictive diagnostics and identifying presymptomatic therapeutic targets; A. L. Marriott, D. A. Gill, C. A. Shaw, R. A. Tasker

7. Tau pathology: A selected view on the current status; I. Gozes

Part III

8. The Use of Biomarkers for Prediction and Prevention of Alzheimers and Parkinsons Diseases; S. A. Mandel & A. D. Korczyn

9. Making clinical trials of Alzheimers disease delay-of-onset a reality by use of a prognostic genetic biomarker; Iris Grossman

10. An update on CSF biomarkers of Parkinsons disease; Peter LeWitt, B Russell Huber, Jing Zhang

Part IV

11. Glaucomatous optic neuropathy: Risk assessment and potential targets for effective prevention and treatments tailored to the patient; O. Golubnitschaja, K. Yeghiazaryan, J. Flammer

Part V

12. Toward a personalized approach in amyotrophic lateral sclerosis: new developments in diagnosis, genetics, pathogenesis and therapies; B. Nefussy & V. E. Drory

13. Recent advances in ALS research: perspectives for personalized clinical application; C. Benkler, D. Offen, E. Melamed, T. Amit, S. Mandel, M. B.H. Youdim, O. Weinreb

Part VI

14. Exercise in Multiple Sclerosis - an Integral Component of Disease Management; A. Dцring, C. F. Pfueller, F. Pau, J. Dцrr

15. Bridging the Informatics Gap between Bench and Bedside: Implications to Neurodegenerative Diseases; A. Shabo (Shvo) & M. Scarpa

Part VII

16. Personalized Medicine In Rare Paediatric Neurometabolic Diseases; R. Tomanin, C. M. Bellettato, F. DAvanzo, A. Zanetti, A. Ceci, D. Begley, M. Scarpa




Neuropathology of Neurodegenerative Diseases Book and Online

Автор: Kovacs
Название: Neuropathology of Neurodegenerative Diseases Book and Online
ISBN: 1107442427 ISBN-13(EAN): 9781107442429
Издательство: Cambridge Academ
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Цена: 14098.00 р.
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Описание: This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases. The book is packaged with a password, giving the user online access to all the text and images.

Neurodegenerative Diseases

Автор: Daniela Galimberti; Elio Scarpini
Название: Neurodegenerative Diseases
ISBN: 1447172426 ISBN-13(EAN): 9781447172420
Издательство: Springer
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Цена: 16769.00 р.
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Описание: This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer`s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases.

Role of Proteases in the Pathophysiology of Neurodegenerative Diseases

Автор: Abel Lajtha; Naren L. Banik
Название: Role of Proteases in the Pathophysiology of Neurodegenerative Diseases
ISBN: 1441933603 ISBN-13(EAN): 9781441933607
Издательство: Springer
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Цена: 19589.00 р.
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Описание: Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects for which experimental results are difficult to interpret.

Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future

Автор: Silvia Mandel
Название: Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future
ISBN: 9400758650 ISBN-13(EAN): 9789400758650
Издательство: Springer
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Цена: 23757.00 р.
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Neurodegenerative Diseases

Автор: Gary Fiskum
Название: Neurodegenerative Diseases
ISBN: 0306452987 ISBN-13(EAN): 9780306452987
Издательство: Springer
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Цена: 30039.00 р.
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Описание: Proceedings of the Fifteenth Washington International Spring Symposium held at The George Washington University, Washington, D.C., May 15-17, 1995

Disease-Modifying Targets in Neurodegenerative Disorders

Автор: Baekelandt, Veerle
Название: Disease-Modifying Targets in Neurodegenerative Disorders
ISBN: 0128051205 ISBN-13(EAN): 9780128051207
Издательство: Elsevier Science
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Цена: 11706.00 р.
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Описание:

Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies.

This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment.

  • Provides a comprehensive overview of how key proteins in neurodegenerative disorders can be used as targets to modify disease progress
  • Summarizes how patients are treated today, providing a glance at future disease management
  • Includes intelligible and informative information that is perfect for non-specialists, medical practitioners, and scientists
  • Written and peer reviewed by outstanding scientists in their respective fields
Molecular Mechanisms of Neurodegenerative Diseases

Автор: Marie-Francoise Chesselet
Название: Molecular Mechanisms of Neurodegenerative Diseases
ISBN: 1617371971 ISBN-13(EAN): 9781617371974
Издательство: Springer
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Цена: 34799.00 р.
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Описание: The field ofneurodegenerative diseases is undergoing an unprecedented revolution. The past decade has seen the identification of new mutation mecha- nisms, such as triplet repeat expansions, and new genes causing familial forms of common neurodegenerative diseases, such as Parkinson's and Alzheimer's diseases. Cellular and animal models based on this genetic information are now available and, importantly, common mechanisms are rapidly emerging among diseases that were once considered unrelated. The field is poised for the development of new therapies based on high throughput screenings and a bet- ter understanding of the molecular and cellular mechanisms leading to neurodegeneration. Molecular Mechanisms of Neurodegenerative Diseases reviews recent progress in this exploding field. By nature, such a book cannot be all inclu- sive. It focuses on Alzheimer's, Parkinson's, and CAG triplet repeat diseases. In the first chapter, Bill Klein reviews the role of A toxicity in the patho- physiology of Alzheimer's disease. This controversial issue is further exam- ined in the context of transgenic models of Alzheimer's disease by LaFerla and colleagues. Sue Griffin and Robert Mrak, and Caleb Finch and collabora- tors, then examine the role of glial cells and inflammation in Alzheimer's disease; a review of the role of proteolysis in the generation of abnormal pro- tein fragments by Hook and Mende-Mueller follows. Therapeutic opportuni- ties offered by a better understanding of Alzheimer's disease pathophysiology are examined by Perry Molinoff and his colleagues at Bristol-Myers Squibb.


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