Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies.
The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics, and molecular dynamics. It also discusses data integration and mining, immunoinformatics, and neuroinformatics. With broad coverage of both basic scientific and clinical applications, this book is suitable for a wide range of readers who may not be scientists but who are also interested in the practice of personalized medicine.
Introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine
Presents a problem-solving oriented methodology to deal with practical problems in various applications
Covers both basic scientific and clinical applications in order to enhance the collaboration between researchers and clinicians
Brings integrative and multidisciplinary approaches to bridge the gaps among various knowledge domains in the field
Автор: Kumar Selvarajoo Название: Immuno Systems Biology ISBN: 1461474590 ISBN-13(EAN): 9781461474593 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book aims to study the immune system in a more integrated manner. It links complex immunological processes with computational analysis and emphasizes the importance of immunology to the mammalian system.
Автор: Peter Wellstead; Mathieu Cloutier Название: Systems Biology of Parkinson`s Disease ISBN: 1493901265 ISBN-13(EAN): 9781493901265 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book shows how methods of systems biology have the potential to accelerate research into diseases like Parkinson`s disease (PD). It comprises a set of eight studies of important aspects of PD, covering all relevant scales of space and time.
Computational Systems Biology: Inference and Modelling provides an introduction to, and overview of, network analysis inference approaches which form the backbone of the model of the complex behavior of biological systems.
This book addresses the challenge to integrate highly diverse quantitative approaches into a unified framework by highlighting the relationships existing among network analysis, inference, and modeling.
The chapters are light in jargon and technical detail so as to make them accessible to the non-specialist reader. The book is addressed at the heterogeneous public of modelers, biologists, and computer scientists.
Автор: Slobodan Vukicevic; Kuber Sampath Название: Bone Morphogenetic Proteins: Systems Biology Regulators ISBN: 3319475053 ISBN-13(EAN): 9783319475059 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Название: Systems biology approach to blood ISBN: 1493920944 ISBN-13(EAN): 9781493920945 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The blood system is multi-scale, from the organism to the organs to cells to intracellular signaling pathways to macromolecule interactions. Blood consists of circulating cells, cellular fragments (platelets and microparticles), and plasma macromolecules. Blood cells and their fragments result from a highly-ordered process, hematopoiesis. Definitive hematopoiesis occurs in the bone marrow, where pluripotential stem cells give rise to multiple lineages of highly specialized cells. Highly-productive and continuously regenerative, hematopoiesis requires a microenvironment of mesenchymal cells and blood vessels. A Systems Biology Approach to Blood is divided into three main sections: basic components, physiological processes, and clinical applications. Using blood as a window, one can study health and disease through this unique tool box with reactive biological fluids that mirrors the prevailing hemodynamics of the vessel walls and the various blood cell types. Many blood diseases, rare and common can and have been exploited using systems biology approaches with successful results and therefore ideal models for systems medicine. More importantly, hematopoiesis offers one of the best studied systems with insight into stem cell biology, cellular interaction, development; linage programing and reprograming that are every day influenced by the most mature and understood regulatory networks.
Описание: This book discusses complex systems and computational biology methods and approaches and their utilazation in understanding and manipulating the acute inflammatory response in settings of sepsis, trauma/hemorrhage, wound healing, and related processes.
Автор: Ale? Prokop; B?la Csuk?s Название: Systems Biology ISBN: 9400768028 ISBN-13(EAN): 9789400768024 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This multi-authored new book looks at a vital strategy which can bring innovation to a market in need of new ideas and new products: Systems Biology (SB).
Автор: Avi Ma`ayan; Ben D. MacArthur Название: New Frontiers of Network Analysis in Systems Biology ISBN: 9400799195 ISBN-13(EAN): 9789400799196 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes cutting-edge experimental and computational advances in emerging sub-fields of systems biology. Coverage includes the study of mammalian embryonic stem cells, new technologies involving mass-spectrometry proteomics and systems pharmacology.
Автор: Asfar S Azmi Название: Systems Biology in Cancer Research and Drug Discovery ISBN: 9400794355 ISBN-13(EAN): 9789400794351 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A collation of chapters from the world`s leading experts in systems biology, this new publication traces its applications to cancer research and focuses on the use of the latest integrated and systems technologies in drug development and personalized medicine.
Автор: Inna N. Lavrik Название: Systems Biology of Apoptosis ISBN: 1489993126 ISBN-13(EAN): 9781489993120 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details the contemporary systems biology studies devoted to apoptotic signaling and examines how systems biology helps to understand life/death decisions made in the cell as well as helps to develop new approaches to rational treatment strategies.
Автор: Alfredo Cesario; Frederick Marcus Название: Cancer Systems Biology, Bioinformatics and Medicine ISBN: 9401783659 ISBN-13(EAN): 9789401783651 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.
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