TGF-? in Human Disease, Aristidis Moustakas; Keiji Miyazawa
Автор: Gael Cristofari Название: Human Retrotransposons in Health and Disease ISBN: 3319483439 ISBN-13(EAN): 9783319483436 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Retrotransposons and the Mammalian Germline.- L1 regulation in Mouse and Human Germ Cells.- Retrotransposon Contribution to Genomic Plasticity.- The Mobilization of Processed Transcripts in Germline and Somatic Tissues.- Neuronal Genome Plasticity: Retrotransposons, Environment and Disease.- Activity of Retrotransposons in Stem Cells and Differentiated Cells.- Environment, Cellular Signaling and L1 activity.- Retrotransposon-derived Regulatory Regions and Transcripts in Stemness.- Roles of Endogenous Retrovirus-encoded Syncytins in Human Placentation.- Alu-Alu Recombinations in Genetic Diseases.- Retrotransposon-driven Transcription and Cancer.- LINE-1 retrotransposons as Neoplastic Biomarkers.- Contribution of Retrotransposable Elements to Aging.
Автор: Maria Kavallaris Название: Cytoskeleton and Human Disease ISBN: 1627038876 ISBN-13(EAN): 9781627038874 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explores our emerging understanding of the molecular and cellular events that drive cytoskeletal mediated diseases including cancer, heart disease, myopathies and skin disorders, and reviews progress toward targeted therapies for treating them.
Автор: Adayabalam Balajee Название: DNA Repair and Human Disease ISBN: 1489998993 ISBN-13(EAN): 9781489998996 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.
Автор: Ariel Ruiz i Altaba Название: Hedgehog-Gli Signaling in Human Disease ISBN: 1489989765 ISBN-13(EAN): 9781489989765 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aim of the book is to disseminate information on this exciting field, to allow students, scientists and the public in general to gain access current information from research leaders and to provide a book that encompasses different aspects of research showing the fusion of basic research in model systems and medicine.
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Edelstein, Charles L. Название: Biomarkers of Kidney Disease ISBN: 0128030143 ISBN-13(EAN): 9780128030141 Издательство: Elsevier Science Рейтинг: Цена: 14654.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Biomarkers of Kidney Disease, Second Edition, focuses on the basic and clinical research of biomarkers in common kidney diseases, detailing the characteristics of an ideal biomarker. The latest techniques for biomarker detection, including metabolomics and proteomics are covered in the book.
This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation, and preeclampsia. New chapters include biomarkers of cardiovascular disease in patients with CKD, biomarkers of Polycystic Kidney Disease, and biomarkers and the role of nanomedicine.
Автор: Aristidis Moustakas; Keiji Miyazawa Название: TGF-? in Human Disease ISBN: 4431544089 ISBN-13(EAN): 9784431544081 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book comprehensively covers the importance of TGF-ss in a wide spectrum of human diseases. It highlights major gaps in knowledge and details the future directions of research that can benefit human medical science.
Автор: Xin-Hua Feng; Pinglong Xu; Xia Lin Название: TGF-? Signaling ISBN: 1493929658 ISBN-13(EAN): 9781493929658 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Chapters provide basic introduction of TGF-ss signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-ss signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway;
Описание: Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease, for the first time, systematically covers the shared structural and functional features of the RTK family.
Автор: D. V. Ablashi; A. Faggioni; G. R. F. Krueger; J. S Название: Epstein-Barr Virus and Human Disease • 1988 ISBN: 1461288525 ISBN-13(EAN): 9781461288527 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The major target cell for EBV infection has now been conclusively identified as the complement receptor-type 2 (CR2), the Cd/Cdg 3 3 receptor on B lymphocyte. It is apparent, however, that other cells also can become infected by EBV, such as epithelial cells in the parotid gland and other epithelial cells in the upper respiratory tract.
Автор: Francis V. Chisari; Michael B.A. Oldstone Название: Transgenic Models of Human Viral and Immunological Disease ISBN: 3642852106 ISBN-13(EAN): 9783642852107 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: effects of cytokines in vivo, focally expressed in unique cells can be established and manipulated, and a variety of autoimmune disorders, mimicking human disease can be constructed. In this volume, these approaches for study of human immunodeficiency virus, hepatitis virus, viruses causing tumors and chronic degenerative disorders are described.
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