Описание: Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure.
Автор: Stanley A. Plotkin MD and Walter Orenstein MD Название: Plotkin`s Vaccines ISBN: 032335761X ISBN-13(EAN): 9780323357616 Издательство: Elsevier Science Рейтинг: Цена: 47012.00 р. Наличие на складе: Поставка под заказ.
Описание:
From the development of each vaccine to its use in reducing disease, Plotkin's Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as an indispensable guide to the enhancement of the well-being of our world, Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field.
Includes complete information for each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, epidemiology, and public health and regulatory issues - plus complete information for each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies.
Analyzes the cost-benefit and cost-effectiveness of different vaccine options.
Helps you clearly visualize concepts and objective data through an abundance of tables and figures.
Covers the new oral cholera and zoster vaccines, as well as newly licensed meningococcal group B vaccines and a newly licensed dengue vaccine.
Brings you up to date on successful human trials of Ebola vaccines, an enterovirus 71 vaccine licensed in China, and new recommendations and changes to polio vaccines.
Features a new chapter on maternal immunization.
Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Описание: This book outlines the critical steps that need to be considered for successful development of various types of nanoparticulate delivery systems for vaccine antigens. Coverage includes clinical evaluations with these novel vaccine technologies.
Автор: Rudolf Valenta; Robert L. Coffman Название: Vaccines against Allergies ISBN: 3642271006 ISBN-13(EAN): 9783642271007 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Vaccines against Allergies celebrates the one hundred year anniversary of allergen-specific immunotherapy. Today allergen-specific immunotherapy is well established as the only allergen-specific and disease-modifying treatment for IgE-mediated allergies and has long-lasting effects.
Автор: Tripp Название: Human Respiratory Syncytial Virus ISBN: 1493936859 ISBN-13(EAN): 9781493936854 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Thisvolume summarizes current techniques; ranging from protocols for virus growth,isolation, quantification and generation of recombinant RSV virus to proceduresfor the efficient characterization of the host immune response to RSVinfection. These techniques are used in numerous laboratories around the worldand are the building blocks that support the majority of RSV virus research. Written in the highly successful Methods in MolecularBiology series format, chapters include introductions to their respectivetopics, lists of the necessary materials and reagents, step-by-step, readilyreproducible laboratory protocols, and tips on troubleshooting and avoidingknown pitfalls.Authoritative and cutting-edge, Humana Respiratory Syncytial Virus:Methods and Protocols aims to ensure successful resultsin the further study of this vital field.
Автор: Yehuda Shoenfeld,Nancy Agmon–Levin Название: Vaccines and Autoimmunity ISBN: 1118663438 ISBN-13(EAN): 9781118663431 Издательство: Wiley Рейтинг: Цена: 22485.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.
Название: Recombinant virus vaccines ISBN: 149396867X ISBN-13(EAN): 9781493968671 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface... Table of Contents... Contributing Authors...
Part I Double-Stranded DNA Viruses
1. Development of Novel Vaccines Against Infectious Diseases Based on Chimpanzee Adenoviral Vector Chao Zhang, Yudan Chi, and Dongming Zhou
2. Development of Recombinant Canarypox Viruses Expressing Immunogens Dйbora Garanzini, Marнa Paula Del Mйdico-Zajac, and Gabriela Calamante
3. Fowl Adenovirus-Based Vaccine Platform Juan C. Corredor, Yanlong Pei, and Йva Nagy
4. Development of Recombinant HSV-Based Vaccine Vectors Richard Voellmy and David Bloom
5. Generating Recombinant Pseudorabies Virus for Use as a Vaccine Platform Feifei Tan, Xiangdong Li, and Kegong Tian
6. Generation and Production of Modified Vaccinia Virus Ankara (MVA) as a Vaccine Vector Vincent Pavot, Sarah Sebastian, Alison V. Turner, Jake Matthews, and Sarah C. Gilbert
7. Poxvirus Safety Analysis in the Pregnant Mouse Model, Vaccinia and Raccoonpox Viruses Rachel L. Roper
Part II Negative Sense Single-Stranded RNA viruses
8. Development of Recombinant Arenavirus-Based Vaccines Luis Martнnez-Sobrido and Juan Carlos de la Torre
9. Development of Recombinant Measles Virus-Based Vaccines Michael D. Mьhlebach and Stefan Hutzler
10. Recombinant Tri-Segmented Pichinde Virus as a Novel Live Viral Vaccine Platform Rekha Dhanwani, Hinh Ly, and Yuying Liang
11. Human Rhinovirus-A1 as an Expression Vector Khamis Tomusange, Danushka Wijesundara, Eric James Gowans, and Branka Grubor-Bauk
12. Generating Recombinant Vesicular Stomatitis Viruses for Use as Vaccine Platforms John B. Ruedas and John H. Connor
Part III Positive Sense Single-Stranded RNA viruses
13. Alphavirus-Based Vaccines Kenneth Lundstrom
Part IV Bacteriophage
14. Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform Jonelle L. Mattiacio, Matt Brewer, and Stephen Dewhurst
15. Bacteriophage T4 as a Nanoparticle Platform to Display and Deliver Pathogen Antigens: Construction of an Effective Anthrax Vaccine Pan Tao, Qin Li, Sathish Shivachandra, and Venigalla B. Rao
Автор: Monica Rinaldi; Daniela Fioretti; Sandra Iurescia Название: DNA Vaccines ISBN: 1493904094 ISBN-13(EAN): 9781493904099 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: DNA Vaccines: Methods and Protocols, Third Edition explores innovative approaches and technologies used to design, deliver, and enhance the efficacy of DNA vaccines.
Автор: R. Pandey; S. H?glund; G. Prasad Название: Veterinary Vaccines ISBN: 1461392284 ISBN-13(EAN): 9781461392286 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the sequences activating suppressor cells are discovered and the rules for presentation of antigens to T and B cells are better worked out.
Автор: Jean-Pierre Kraehenbuhl; Marian R. Neutra Название: Defense of Mucosal Surfaces: Pathogenesis, Immunity and Vaccines ISBN: 3642641946 ISBN-13(EAN): 9783642641947 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mucosal immunity encompasses a broad field of research that includes areas of epithelial cell and molecular biology, molecular and cellular immunology, microbiology, virology, and vaccinology. It provides an overview of the components of the mucosal immune system, and the basic science relevant to mucosal vaccination.
Автор: Dushyant Varshney; Manmohan Singh Название: Lyophilized Biologics and Vaccines ISBN: 149392382X ISBN-13(EAN): 9781493923823 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface.- Part I - Lyophilization History and Fundamentals.- History of Lyophilization.- Heterogeneity of protein environments in frozen solutions and in the dried state.- Advance understanding of buffer behavior during lyophilization.- Advances in Instrumental Analysis Applied to the Development of Lyophilization Cycles.- New Developments in Controlled Nucleation: Commercializing VERISEQ(R) Nucleation technology.- Part II - Lyophilized Biologics and Vaccines - Modality Considerations.- Lyophilized Biologics.- Lyophilization of Therapeutic Proteins in Vials - Process Scale-up and Advances in Quality by Design.- Advances in Process Analytical Technology in Freeze Drying.- Process Scale-up and Optimization of Lyophilized Vaccine Products.- Stabilization of Plasmid DNA and Lipid-based Therapeutics as Dehydrated Formulations.- Part III - Advances in Alternate Drying.- Alternatives to Vial Lyophilization.- Spray Drying of Biopharmaceuticals.- Current Trends and Advances in Bulk Crystallization and Freeze Drying of Biopharmaceuticals.- Case Studies and Examples of Biopharmaceutical Modalities.- Processed by Bulk Crystallization or Bulk Freeze Drying.- Part IV- Regulatory, Packaging and Technology Transfer Considerations.- Lyophilization of Biologics - An FDA Perspective.- Recent Trends in Lyophilized Delivery Devices and Packaging.- Lyophilization Technology Transfer towards Product Launch.
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