Proteases in Health and Disease, Sajal Chakraborti; Naranjan S. Dhalla
Автор: Nigel M Hooper; Uwe Lendeckel Название: The ADAM Family of Proteases ISBN: 1441937757 ISBN-13(EAN): 9781441937759 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The ADAM Family of Proteases provides the first comprehensive review of the roles of ADAMs and the related ADAMTS proteases in biology and disease.
Enzymology at the Membrane Interface: Intramembrane Proteases, Volume 584, the latest release in the Methods in Enzymology series, covers a subset of enzymes that work in the environment of the biological cell membrane. This field, called interfacial enzymology, involves a special series of experimental approaches for the isolation and study of these enzymes.
Автор: Nathalie Vergnolle; Michel Chignard Название: Proteases and Their Receptors in Inflammation ISBN: 3034803427 ISBN-13(EAN): 9783034803427 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or inflammatory cells, thereby contributing to the innate immune response.
This volume presents all advances in our knowledge of the role proteases and their inhibitors play in various diseases associated with inflammatory response. Mechanisms involved in protease signaling to cells are presented, and the different types of proteases that are present at inflammatory sites and their effects on the course of inflammation are discussed. Finally, the evidence for considering proteases and their receptors as potential molecular targets for therapeutic interventions in the treatment of inflammatory diseases is discussed in the context of specific organ inflammatory pathologies (the lung, gastrointestinal tract, skin, joints, etc.).
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Автор: Naranjan S. Dhalla; Sajal Chakraborti Название: Role of Proteases in Cellular Dysfunction ISBN: 149394634X ISBN-13(EAN): 9781493946341 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume explores the role of proteases in various diseases. It provides information on the pathogenesis of cellular dysfunction, with strong emphasis on identifying proteases and their endogenous inhibitors as targets for drug development.
Название: Proteases in Health and Disease ISBN: 1461492327 ISBN-13(EAN): 9781461492320 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area.
Автор: Walter H. Horl Название: PROTEASES: Potential Role in Health and Disease ISBN: 1461593573 ISBN-13(EAN): 9781461593577 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Klaus, von der Helm; Bruce D. Korant; John C. Cher Название: Proteases as Targets for Therapy ISBN: 3642630235 ISBN-13(EAN): 9783642630231 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Uwe Lendeckel; Nigel M Hooper Название: Proteases in the Brain ISBN: 1441935738 ISBN-13(EAN): 9781441935731 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
In all organs of the body, proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to this, with proteases having emerging roles in synaptic plasticity, memory, neurodegenerative disorders such as Alzheimer's, Parkinson's and prion diseases, ischemia and traumatic brain injury, inflammatory and infectious diseases, and tumor progression. Proteases in the Brain brings together a wide range of topics under this central theme and highlights the large number of proteases involved in these normal and disease processes.
Proteases in the Brain reviews the role and regulation of proteases in, Alzheimer's disease, brain ischemia and traumatic brain injury, human glioma, inflammatory and infectious diseases of the central nervous system, metabolism of the prion protein, modulating synaptic activity, multiple sclerosis, neuronal plasticity and memory consolidation, Parkinson's disease, processing, conversion and inactivation of neuropeptides.
Proteases in the Brain is a timely and useful source of information both for those well-versed in the role of proteases in the brain, and for those who are beginning to realize the important role of this family of enzymes in brain function and dysfunction.
Автор: Vito Turk Название: Proteases New Perspectives ISBN: 3034897502 ISBN-13(EAN): 9783034897501 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an account of the recent advances in our understanding of the role of proteases under physiological and pathological conditions.
Автор: Chakraborti Sajal Название: Role of Proteases in Cellular Dysfunction ISBN: 1461490987 ISBN-13(EAN): 9781461490982 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume explores the role of proteases in various diseases. It provides information on the pathogenesis of cellular dysfunction, with strong emphasis on identifying proteases and their endogenous inhibitors as targets for drug development.
Автор: Klaudia Brix; Walter St?cker Название: Proteases: Structure and Function ISBN: 3709119391 ISBN-13(EAN): 9783709119396 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proteolysis is an irreversible posttranslational modification affecting each and every protein, from its biosynthesis to its degradation. This volume explores both the structure and function of proteases.