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Proteases in the Brain, Uwe Lendeckel; Nigel M Hooper


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Автор: Uwe Lendeckel; Nigel M Hooper
Название:  Proteases in the Brain
ISBN: 9781441935731
Издательство: Springer
Классификация:


ISBN-10: 1441935738
Обложка/Формат: Paperback
Страницы: 384
Вес: 0.53 кг.
Дата издания: 25.11.2010
Серия: Proteases in Biology and Disease
Язык: English
Размер: 229 x 152 x 21
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:

In all organs of the body, proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to this, with proteases having emerging roles in synaptic plasticity, memory, neurodegenerative disorders such as Alzheimers, Parkinsons and prion diseases, ischemia and traumatic brain injury, inflammatory and infectious diseases, and tumor progression. Proteases in the Brain brings together a wide range of topics under this central theme and highlights the large number of proteases involved in these normal and disease processes.

Proteases in the Brain reviews the role and regulation of proteases in, Alzheimers disease, brain ischemia and traumatic brain injury, human glioma, inflammatory and infectious diseases of the central nervous system, metabolism of the prion protein, modulating synaptic activity, multiple sclerosis, neuronal plasticity and memory consolidation, Parkinsons disease, processing, conversion and inactivation of neuropeptides.

Proteases in the Brain is a timely and useful source of information both for those well-versed in the role of proteases in the brain, and for those who are beginning to realize the important role of this family of enzymes in brain function and dysfunction.




Proteases in Health and Disease

Название: Proteases in Health and Disease
ISBN: 1461492327 ISBN-13(EAN): 9781461492320
Издательство: Springer
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Цена: 23508.00 р.
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Описание: In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area.

Proteases in Health and Disease

Автор: Sajal Chakraborti; Naranjan S. Dhalla
Название: Proteases in Health and Disease
ISBN: 1493948539 ISBN-13(EAN): 9781493948536
Издательство: Springer
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Цена: 20896.00 р.
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Описание: In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area.

Serine Proteases and Their Serpin Inhibitors in the Nervous System

Автор: Barry W. Festoff
Название: Serine Proteases and Their Serpin Inhibitors in the Nervous System
ISBN: 1468483595 ISBN-13(EAN): 9781468483598
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Proceedings of a NATO ARW held in Maratea, Italy, July 2-8, 1989

Proteases and Their Receptors in Inflammation

Автор: Nathalie Vergnolle; Michel Chignard
Название: Proteases and Their Receptors in Inflammation
ISBN: 3034803427 ISBN-13(EAN): 9783034803427
Издательство: Springer
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Цена: 26120.00 р.
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Описание:

Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or inflammatory cells, thereby contributing to the innate immune response.

This volume presents all advances in our knowledge of the role proteases and their inhibitors play in various diseases associated with inflammatory response. Mechanisms involved in protease signaling to cells are presented, and the different types of proteases that are present at inflammatory sites and their effects on the course of inflammation are discussed. Finally, the evidence for considering proteases and their receptors as potential molecular targets for therapeutic interventions in the treatment of inflammatory diseases is discussed in the context of specific organ inflammatory pathologies (the lung, gastrointestinal tract, skin, joints, etc.).

"

Role of Proteases in Cellular Dysfunction

Автор: Chakraborti Sajal
Название: Role of Proteases in Cellular Dysfunction
ISBN: 1461490987 ISBN-13(EAN): 9781461490982
Издательство: Springer
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Цена: 28734.00 р.
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Описание: This volume explores the role of proteases in various diseases. It provides information on the pathogenesis of cellular dysfunction, with strong emphasis on identifying proteases and their endogenous inhibitors as targets for drug development.

Proteases New Perspectives

Автор: Vito Turk
Название: Proteases New Perspectives
ISBN: 3034897502 ISBN-13(EAN): 9783034897501
Издательство: Springer
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Цена: 13974.00 р.
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Описание: This book provides an account of the recent advances in our understanding of the role of proteases under physiological and pathological conditions.

Enzymology at the Membrane Interface: Intramembrane Proteases,584

Автор: Gelb, Michael H
Название: Enzymology at the Membrane Interface: Intramembrane Proteases,584
ISBN: 0128122137 ISBN-13(EAN): 9780128122136
Издательство: Elsevier Science
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Цена: 24423.00 р.
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Описание:

Enzymology at the Membrane Interface: Intramembrane Proteases, Volume 584, the latest release in the Methods in Enzymology series, covers a subset of enzymes that work in the environment of the biological cell membrane. This field, called interfacial enzymology, involves a special series of experimental approaches for the isolation and study of these enzymes.

Proteases in Tissue Remodelling of Lung and Heart

Автор: Uwe Lendeckel; Nigel M. Hooper
Название: Proteases in Tissue Remodelling of Lung and Heart
ISBN: 1461347866 ISBN-13(EAN): 9781461347866
Издательство: Springer
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Цена: 13974.00 р.
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Описание:

Proteases in Tissue Remodelling of Lung and Heart is unique for its comprehensive presentation of protease function in lung and heart under both physiological conditions and major diseases manifesting in these two organs. The individual chapters have been written by leaders in the field who paid much attention to outline in great detail the role of proteases in the pathogenesis, diagnosis and treatment of disease. Available animal models (of disease, transgenic, or knock-out) are extensively referred to and experimental data obtained thereby are discussed in the context of patient-derived data.

Newcomers to the field and interested non-specialists will take advantage of the extensive introduction to individual proteases, protease families and the diseases. Understanding is greatly facilitated by the clear and condensed presentation of summarised data in tables and graphs. Thus, the book should be a valuable source for both clinicians and researchers interested in protease function and/or diseases of lung and heart.

Proteases in Tissue Remodelling of Lung and Heart
*is devoted to proteases in lung and heart specifically and extensively,
*covers major diseases of the lung and heart,
*extensively introduces individual proteases (or families thereof),
*presents up-to-date patient-derived and experimental data,
*covers most aspects of protease function in disease.

Role of Proteases in the Pathophysiology of Neurodegenerative Diseases

Автор: Abel Lajtha; Naren L. Banik
Название: Role of Proteases in the Pathophysiology of Neurodegenerative Diseases
ISBN: 1441933603 ISBN-13(EAN): 9781441933607
Издательство: Springer
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Цена: 19589.00 р.
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Описание: Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects for which experimental results are difficult to interpret.

PROTEASES: Potential Role in Health and Disease

Автор: Walter H. Horl
Название: PROTEASES: Potential Role in Health and Disease
ISBN: 1461593573 ISBN-13(EAN): 9781461593577
Издательство: Springer
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Цена: 6986.00 р.
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Proteases II

Автор: Walter H. H?rl; August Heidland
Название: Proteases II
ISBN: 1461283132 ISBN-13(EAN): 9781461283133
Издательство: Springer
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Цена: 12157.00 р.
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Описание: We are pleased to present to our readers the Proceedings of the Second International Symposium "Proteases: Potential Role in Health and Disease" which was held in Rothenburg ob der Tauber (FRG) during May 17-20, 1987. The topics discussed included those dealing with the physiology and pathophysiology of proteases and their inhibitors, the inter- actions of proteases and hormones, the kallikrein-kinin, com- plement and coagulation system, the function of proteases in arthritis, malignoma, pancreatitis, intestinal tract, lung and kidney disease as well as in hypercatabolic states (acute renal failure, multiple trauma and septicemia). Furthermore some reports dealed with the role of proteases during extracorporeal circulation. The papers presented answered many questions, but raised many more concerning the significance of proteases and their in- hibitors in clinical medicine. It was unfortunately impossible in this volume, to include the extended, lively and stimulating discussions which were enjoyed by the participiants during the conference. The meeting has provided a unique framework for close inter- action between scientists from various disciplines, including molecular biology, biochemistry, physiology, surgery, anaesthe- siology, endocrinology, hematology, pneumatology and nephrology.

The ADAM Family of Proteases

Автор: Nigel M Hooper; Uwe Lendeckel
Название: The ADAM Family of Proteases
ISBN: 1441937757 ISBN-13(EAN): 9781441937759
Издательство: Springer
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Цена: 26120.00 р.
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Описание: The ADAM Family of Proteases provides the first comprehensive review of the roles of ADAMs and the related ADAMTS proteases in biology and disease.


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