Автор: Kwok Pui-Yan Название: Single Nucleotide Polymorphisms / Methods and Protocols ISBN: 0896039684 ISBN-13(EAN): 9780896039681 Издательство: Springer Цена: 5809.00 р. Наличие на складе: Есть (2 шт.) Описание: Pui-Yan Kwok, MD, PhD, has assembled a comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.
Описание: Human Chromosome Variation: Heteromorphism and Polymorphism was formerly printed under the title “Atlas of Human Chromosome Heteromorphism”. The Atlas has become a standard reference book in most cytogenetic laboratories and is cited as a significant reference in ISCN 2009. This revised version has updated and retained the most useful pictorial sections of the first edition, including the comprehensive review of normal and “not-so-normal” variations of the human karyotype with summaries and extensive reference lists organized by chromosome number. This updated edition features concise background information on chromosome methods and applications, essential information on heteromorphism frequencies in normal and clinical populations as well as new listing and discussions of euchromatic, subtelomeric and FISH variants. The addition of two new sections make this an even more valuable reference than before. A section on common and rare fragile sites includes a short historical discussion, definitions and an extensive table of officially recognized sites that includes the HUGO name, chromosomal location, methods of induction, genes and references to the most recent molecular characterization. A new section on array CGH discusses the clinical challenge of interpreting copy number variations (CNVs) revealed by this newest technology, gives examples of various levels of interpretation and lists the several most common websites used in this interpretation.
Автор: D.J. Galton; G. Assmann Название: DNA Polymorphisms as Disease Markers ISBN: 1461366402 ISBN-13(EAN): 9781461366409 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ARW held in London, UK, September 26-28, 1990
Автор: Danny M. Hatters; Anthony J. Hannan Название: Tandem Repeats in Genes, Proteins, and Disease ISBN: 1627034374 ISBN-13(EAN): 9781627034371 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details methods covering the analysis of tandem repeats in DNA, RNA and protein, in healthy and diseased states. It features step-by-step, readily reproducible laboratory protocols as well as lists of the necessary materials and reagents.
Автор: Danny M. Hatters; Anthony J. Hannan Название: Tandem Repeats in Genes, Proteins, and Disease ISBN: 1493963007 ISBN-13(EAN): 9781493963003 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details methods covering the analysis of tandem repeats in DNA, RNA and protein, in healthy and diseased states. It features step-by-step, readily reproducible laboratory protocols as well as lists of the necessary materials and reagents.
Автор: W.D. Hamilton; J.C. Howard Название: Infection, Polymorphism and Evolution ISBN: 9401065233 ISBN-13(EAN): 9789401065238 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Resulting from a Royal Society discussion meeting, this volume presents a short review of the topic of parasite-host co-evolution. Current thinking on evolution in parasites, viruses and other pathogens is discussed.
Автор: Yoshinori Kohwi; Cynthia T. McMurray Название: Trinucleotide Repeat Protocols ISBN: 1493959719 ISBN-13(EAN): 9781493959716 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Coverage in this volume includes an overview of trinucleotide repeat diseases, synaptic plasticity, embryonic stem (ES) cell-related protocols with a focus on HD, RNA-related protocols, and analysis of epigenetic modification in fragile X syndrome.
Автор: Yoshinori Kohwi; Cynthia T. McMurray Название: Trinucleotide Repeat Protocols ISBN: 1627034102 ISBN-13(EAN): 9781627034104 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Coverage in this volume includes an overview of trinucleotide repeat diseases, synaptic plasticity, embryonic stem (ES) cell-related protocols with a focus on HD, RNA-related protocols, and analysis of epigenetic modification in fragile X syndrome.
Автор: Hardy J. Rideout Название: Leucine-Rich Repeat Kinase 2 (LRRK2) ISBN: 331949967X ISBN-13(EAN): 9783319499673 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction.
Автор: Lubov T. Timchenko Название: Triple Repeat Diseases of the Nervous Systems ISBN: 1461349311 ISBN-13(EAN): 9781461349310 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: World of Unstable Mutations The book "Triplet Repeat Diseases of the Nervous System" overviews the lat- est data on several disorders associated with unstable mutations. The number of polymorphic mutations and diseases caused by these mutations is increasing almost every month.
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