Leucine-Rich Repeat Kinase 2 (LRRK2), Hardy J. Rideout

Автор: Anthony J. Hannan
Название: Tandem Repeat Polymorphisms
ISBN: 1493954482 ISBN-13(EAN): 9781493954483
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This book addresses the role of tandem repeat polymorphisms (TRPs) in genetic plasticity, evolution, development, biological processes, neural diversity, brain function, dysfunction and disease.

Автор: Yoshinori Kohwi; Cynthia T. McMurray
Название: Trinucleotide Repeat Protocols
ISBN: 1627034102 ISBN-13(EAN): 9781627034104
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Coverage in this volume includes an overview of trinucleotide repeat diseases, synaptic plasticity, embryonic stem (ES) cell-related protocols with a focus on HD, RNA-related protocols, and analysis of epigenetic modification in fragile X syndrome.

Автор: Lodewijk V. Dekker
Название: Protein Kinase C
ISBN: 1441934197 ISBN-13(EAN): 9781441934192
Издательство: Springer
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Цена: 26552.00 р.
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Описание: Protein Kinase C is a pivotal component of the mechanism that allows a cell to respond to its changing environment. The remaining chapters contain overviews of the function of Protein Kinase C, both in lower organisms and in mammalian cells, the latter with a focus on immune cells and nerve cells.

Автор: H. Lang
Название: Creatine Kinase Isoenzymes
ISBN: 3540107142 ISBN-13(EAN): 9783540107149
Издательство: Springer
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Цена: 15372.00 р.
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Описание: No one has counted the enzymes in the human organism, and probably their profuse number can only be estimated from the restrictions the finite mass of genetic material imposes.

Автор: Nancy Y. Ip; Li-Huei Tsai
Название: Cyclin Dependent Kinase 5 (Cdk5)
ISBN: 1489987746 ISBN-13(EAN): 9781489987747
Издательство: Springer
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Цена: 25853.00 р.
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Описание: This book provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5. It further reviews the potential implication of Cdk5 in the treatment of neurodegenerative diseases.

Автор: Hideyuki Mukai
Название: Protein Kinase Technologies
ISBN: 1493962426 ISBN-13(EAN): 9781493962426
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This book examines recent methodologies and techniques generally applicable to protein kinase research as well as to individual protein kinases which require special attention in neuroscience. Covers recent progress in individual protein.

Автор: Mario D. Cordero; Benoit Viollet
Название: AMP-activated Protein Kinase
ISBN: 3319435876 ISBN-13(EAN): 9783319435879
Издательство: Springer
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Цена: 30745.00 р.
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Описание: AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes. This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease. 

Автор: Salomons
Название: Creatine and Creatine Kinase in Health and Disease
ISBN: 9048176522 ISBN-13(EAN): 9789048176526
Издательство: Springer
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Цена: 32144.00 р.
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Описание: This volume places emphasis on the intricate interplay between creatine and creatine kinase function on one hand and proper brain function, neurodegenerative disease and/or neuroprotection on the other. The book, compiled by outstanding experts, provides a key reference summarizing the state-of-the-art in creatine and creatine kinase research.

Автор: Christian Rommel; Bart Vanhaesebroeck; Peter K. Vo
Название: Phosphoinositide 3-kinase in Health and Disease
ISBN: 3642265227 ISBN-13(EAN): 9783642265228
Издательство: Springer
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Цена: 34799.00 р.
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Описание: PI3K is at the forefront of drug development with the first clinical trials of PI3K pathway inhibitors in progress. This book offers an overview of some key discoveries in the PI3K area and their impact, and includes thoughts on the current state of the field.