Автор: Alastair D. Reith Название: Protein Kinase Protocols ISBN: 1617371416 ISBN-13(EAN): 9781617371417 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Hideyuki Mukai Название: Protein Kinase Technologies ISBN: 1493962426 ISBN-13(EAN): 9781493962426 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines recent methodologies and techniques generally applicable to protein kinase research as well as to individual protein kinases which require special attention in neuroscience. Covers recent progress in individual protein.
Автор: Hicham Zegzouti; Said A. Goueli Название: Kinase Screening and Profiling ISBN: 1493949233 ISBN-13(EAN): 9781493949236 Издательство: Springer Рейтинг: Цена: 13275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. HTRF Kinase Assay Development and Methods in Inhibitor Characterization Yong Jia, Mari Manuia, and Jose Juarez
2. Application of Eukaryotic Elongation Factor-2 Kinase (eEF-2K) for Cancer Therapy: Expression, Purification, and High-Throughput Inhibitor Screening Clint D. J. Tavares, Ashwini K. Devkota, Kevin N. Dalby, and Eun Jeong Cho 3. Recombinant Kinase Production and Fragment Screening by NMR Spectroscopy Byeonggu Han and Hee-Chul Ahn 4. Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase and PI5P4Kα Lipid Kinase Mindy I. Davis, Douglas S. Auld, and James Inglese 5. Using Bioluminescent Kinase Profiling Strips to Identify Kinase Inhibitor Selectivity and Promiscuity Hicham Zegzouti, Jacquelyn Hennek, and Said A. Goueli 6. Measuring Activity of Phosphoinositide Lipid Kinases Using a Bioluminescent ADP-Detecting Assay Andrew W. Tai and Jolanta Vidugiriene
7. A High-Throughput Radiometric Kinase Assay Krisna C. Duong-Ly and Jeffrey R. Peterson 8. A High Content Assay to Screen for Modulators of EGFR Function Christophe Antczak and Hakim Djaballah 9. Monitoring Protein Kinase Expression and Phosphorylation in Cell Lysates with Antibody Microarrays Hong Zhang, Xiaoqing Shi, and Steven Pelech
10. From Enzyme to Whole Blood: Sequential Screening Procedure for Identification and Evaluation of p38 MAPK Inhibitors Silke M. Bauer, Jakub M. Kubiak, Ulrich Rothbauer, and Stefan Laufer
11. Genetically Encoded Fluorescent Indicators to Visualize Protein Phosphorylation in Living Cells Moritoshi Sato and Yoshio Umezawa
12. Characterization of an Engineered Src Kinase to Study Src Signaling and Biology Leanna R. Gentry, Andrei V. Karginov, Klaus M. Hahn, and Channing J. Der
13. Screening One-Bead-One-Compound Peptide Libraries for Optimal Kinase Substrates Thi B. Trinh and Dehua Pei
14. Determination of the Substrate Specificity of Protein Kinases with Peptide Micro- and Macroarrays Shenshen Lai, Dirk F.H. Winkler, Hong Zhang, and Steven Pelech 15. Rapid Identification of Protein Kinase Phosphorylation Site Motifs Using Combinatorial Peptide Libraries Chad J. Miller and Benjamin E. Turk
Автор: Alexandra C. Newton Название: Protein Kinase C Protocols ISBN: 1617373354 ISBN-13(EAN): 9781617373350 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since the discovery that protein kinase C (PKC) transduces the ab- dance of signals that result in phospholipid hydrolysis, this enzyme has been at the forefront of research in signal transduction. The book ends with a presentation of genetic approaches to study PKC (Part X) and a discussion of approaches used to study PKC in disease (Part XI).
Автор: Khalil Ahmed; Olaf-Georg Issinger; Ryszard Szyszka Название: Protein Kinase CK2 Cellular Function in Normal and Disease States ISBN: 3319145436 ISBN-13(EAN): 9783319145433 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Protein kinase CK2 (formerly casein kinase II or 2) is known to play a critical role in the control of cell growth and cell death and is thus intimately involved in the development of cancer. More specifically, CK2 has been found to be elevated in all cancers examined. While CK2 levels are known to be high in proliferating normal cells, CK2 has also been found to be a potent suppressor of apoptosis and is a link to the cancer cell phenotype, which is characterized by deregulation of both cell proliferation and cell death. Indeed, it would appear that CK2 impacts many of the hallmarks of cancer and it has now gained considerable attention as a potential target for cancer therapy. Protein Kinase CK2 and Cellular Function in Normal and Disease States increases knowledge of the role of CK2 in the development of cellular dysfunction and emphasizes that this protein may serve as a target of drug development for improved cancer therapy. In addition, it is a handy tool that provides cancer researchers, graduate students, and all scientists involved in CK2 research with one main source for the latest advances in CK2 research.
Автор: Hardy J. Rideout Название: Leucine-Rich Repeat Kinase 2 (LRRK2) ISBN: 331949967X ISBN-13(EAN): 9783319499673 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction.
Автор: H. Lang Название: Creatine Kinase Isoenzymes ISBN: 3540107142 ISBN-13(EAN): 9783540107149 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: No one has counted the enzymes in the human organism, and probably their profuse number can only be estimated from the restrictions the finite mass of genetic material imposes.
Автор: Nancy Y. Ip; Li-Huei Tsai Название: Cyclin Dependent Kinase 5 (Cdk5) ISBN: 1489987746 ISBN-13(EAN): 9781489987747 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5. It further reviews the potential implication of Cdk5 in the treatment of neurodegenerative diseases.
Автор: Mario D. Cordero; Benoit Viollet Название: AMP-activated Protein Kinase ISBN: 3319435876 ISBN-13(EAN): 9783319435879 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes. This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease.
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