Peptide Nucleic Acids, Peter E Nielsen; Daniel H. Appella
Автор: JORGEN KJEMS, Elena Ferapontova, Kurt V. Gothelf Название: Nucleic Acid Nanotechnology ISBN: 3642388140 ISBN-13(EAN): 9783642388149 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book surveys the intersection of nucleic acid research with nanotechnology, including advances in synthetic modifications, applications in bioengineering, nanoscale design, medicine, genetic analysis, chemistry, molecular biology and material science.
Автор: Val?rie Gabelica Название: Nucleic Acids in the Gas Phase ISBN: 3642548415 ISBN-13(EAN): 9783642548413 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book gives physical chemists a broader view of potential biological applications of their techniques for the study of nucleic acids in the gas phase. It provides organic chemists, biophysicists, and pharmacologists with an introduction to new techniques they can use to find the answers to yet unsolved questions. Laboratory sciences have bloomed with a variety of techniques to decipher the properties of the molecules of life. This volume introduces techniques used to investigate the properties of nucleic acids in the absence of solvent. It highlights the specificities pertaining to the studies of nucleic acids, although some of the techniques can similarly be applied to the study of other biomolecules, like proteins. The first part of the book introduces the techniques, from the transfer of nucleic acids to the gas-phase, to their detailed physico-chemical investigation. Each chapter is devoted to a specific molecular property, and illustrates how various approaches (experimental and theoretical) can be combined for the interpretation. The second part of the book is devoted to applying the gas-phase approaches to solve specific questions related to the biophysics, biochemistry or pharmacology of nucleic acids.
Автор: Mario Barbatti; Antonio Carlos Borin; Susanne Ullr Название: Photoinduced Phenomena in Nucleic Acids II ISBN: 3319132717 ISBN-13(EAN): 9783319132716 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole.
Автор: Volker A. Erdmann; Wojciech T. Markiewicz; Jan Bar Название: Chemical Biology of Nucleic Acids ISBN: 3642544517 ISBN-13(EAN): 9783642544514 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology. Topics include pre-biology; the establishment of the genetic code; isomerization of RNA; damage of nucleobases in RNA; the dynamic structure of nucleic acids and their analogs in DNA replication, extra- and intra-cellular transport; molecular crowding by the use of ionic liquids; new technologies enabling the modification of gene expression via editing of therapeutic genes; the use of riboswitches; the modification of mRNA cap regions; new approaches to detect appropriately modified RNAs with EPR spectroscopy and the use of parallel and high-throughput techniques for the analysis of the structure and new functions of nucleic acids. This volume discusses how chemistry can add new frontiers to the field of nucleic acids in molecular medicine, biotechnology and nanotechnology and is not only an invaluable source of information to chemists, biochemists and life scientists but will also stimulate future research.
Автор: Peter E Nielsen; Daniel H. Appella Название: Peptide Nucleic Acids ISBN: 1627035524 ISBN-13(EAN): 9781627035521 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume details methods and protocols in PNA chemistry. It features step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Автор: Fritz Eckstein; David M. J. Lilley Название: Nucleic Acids and Molecular Biology ISBN: 3642837115 ISBN-13(EAN): 9783642837111 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A wide range of topics are covered, including articles on nucleic acid structure, through their interactions with proteins to the control of gene expression. Gene transcription is also covered, from the points of view of DNA methylation, mammalian ribosomal and avian lysozyme genes, and the control of transcription in the proto-oncogene c-fos.
Описание: This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications.
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