Next-Generation MicroRNA Expression Profiling Technology, Jian-Bing Fan

Автор: Zhang
Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells
ISBN: 1607617684 ISBN-13(EAN): 9781607617686
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.

Автор: Malik Yousef; Jens Allmer
Название: miRNomics: MicroRNA Biology and Computational Analysis
ISBN: 1493962647 ISBN-13(EAN): 9781493962648
Издательство: Springer
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Цена: 16769.00 р.
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Описание: In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective.

Автор: Rani
Название: MicroRNA Profiling
ISBN: 1493965220 ISBN-13(EAN): 9781493965229
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This volume includes comprehensive descriptions of miRNA biogenesis and their role in the development and progression of various human diseases. The first few chapters of MicroRNA Profiling: Methods and Protocols discuss the effects of over-expressing and repressing of a target miRNA and their effects on cell viability and proliferation. The next few chapters explore the protocols for total RNA isolation from cells and cell-derived product including formalin fixed paraffin embedded tissue and plant tissue. The last few chapters discuss isolation and characterization of exosomes from medium conditioned by cell lines, serum, and plasma specimens. This book also includes discussions of several software tools, such as miRandola, PicTar, DIANA, and miRWalk. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, MicroRNA Profiling: Methods and Protocols is a valuable resource for anyone interested in the field of Micro RNAs.

Автор: Zhiguo Wang; Baofeng Yang
Название: MicroRNA Expression Detection Methods
ISBN: 3642425186 ISBN-13(EAN): 9783642425189
Издательство: Springer
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Цена: 28732.00 р.
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Описание: This book provides comprehensive descriptions of the innovative strategies and methodologies for detecting miRNA expression as well as their application in miRNA research and their potential as tools for clinical diagnosis and prognosis.

Автор: Suresh Alahari
Название: MicroRNA in Cancer
ISBN: 9401784930 ISBN-13(EAN): 9789401784931
Издательство: Springer
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Цена: 15672.00 р.
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Описание: This book explores the rapidly emerging field of microRNA biology, highlighting the importance of microRNAs in cancer. This first reference of its kind will benefit working scientists in cancer biology, as well as advanced undergraduate and graduate students.

Автор: Tamas Dalmay
Название: MicroRNA Detection and Target Identification
ISBN: 1493968645 ISBN-13(EAN): 9781493968640
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This collection of miRNA detection and target identification protocols details new developments in traditional detection such as northern blot, quantitative real-time PCR and in situ hybridization, and guides through novel approaches such as nanotechnology, microfluidics, based detection methods, miRNAs as biomarkers and others.

Автор: Fazlul H. Sarkar
Название: MicroRNA Targeted Cancer Therapy
ISBN: 3319051334 ISBN-13(EAN): 9783319051338
Издательство: Springer
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Цена: 23508.00 р.
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Описание: The most attractive feature of miRNAs is that one miRNA can regulate many target genes (mRNAs) and thus miRNA targeted therapy is highly promising because multiple genes could be regulated by targeting a single miRNA, which becomes very important for the killing of highly heterogeneous populations of cancer cells within a tumor mass.

Автор: Ulf Schmitz; Olaf Wolkenhauer; Julio Vera
Название: MicroRNA Cancer Regulation
ISBN: 9402400796 ISBN-13(EAN): 9789402400793
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book discusses the role of microRNAs in the formation and progression of solid tumors. The main focus is on computational methods and applications, together with experimental techniques used to approach all aspects of microRNA regulation in cancer.

Автор: Wei Wu
Название: MicroRNA and Cancer
ISBN: 1493957740 ISBN-13(EAN): 9781493957743
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Authoritative and cutting-edge, this book provides the basic principles of experimental and computational methods for microRNA study in cancer research. It provides a firm grounding for those who wish to further develop their own applications.

Автор: Shree Ram Singh; Pranela Rameshwar
Название: MicroRNA in Development and in the Progression of Cancer
ISBN: 1493944916 ISBN-13(EAN): 9781493944910
Издательство: Springer
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Цена: 19589.00 р.
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Описание: Altered expression of particular miRNAs has been implicated in the onset and development of cancer and could be used as potential biomarkers for the disease.Recently, many studies have found miRNAs have crucial regulatory roles in Cancer stem cells (CSCs) a kind of tumor initiating cells (TICs) and dormancy.

Автор: Zhiguo Wang
Название: MicroRNA Interference Technologies
ISBN: 3642101518 ISBN-13(EAN): 9783642101519
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book presents an overview of up-to-date knowledge of MicroRNAs (miRNAs) biology and their potential as therapeutic targets for human disease. It also gives an introduction of the new concept of miRNA interference (miRNAi).

Автор: Singh Shree Ram
Название: MicroRNA in Development and in the Progression of Cancer
ISBN: 1489980644 ISBN-13(EAN): 9781489980649
Издательство: Springer
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Цена: 23757.00 р.
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Описание: miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression. Since we have hundreds of miRNAs, the major challenge is now to understand their specific biological function. In fact the experimental evidence suggests that signaling pathways could be ideal candidates for miRNA-mediated regulation. Several studies suggest that miRNAs affect the responsiveness of cells to signaling molecules such as WNT, Notch, TGF-? and EGFR. Altered expression of particular miRNAs has been implicated in the onset and development of cancer and could be used as potential biomarkers for the disease. Recently, many studies have found miRNAs have crucial regulatory roles in Cancer stem cells (CSCs) a kind of tumor initiating cells (TICs) and dormancy. Findings also suggest that DNA methylation may be important in regulating the expression of many miRNAs in several cancer initiating cells. Several miRNAs are known to either upregulated or downregulated in CSCs when compared to non-cancerous cells from the same tissues. CSCs are a small subpopulation of cells identified in a variety of tumors and involve in self-renewal, differentiation, chemoresistance and tumorigenesis. The volume will give a comprehensive account of important advancements in the area of miRNAs and cancer.