RNA Mapping, M. Lucrecia Alvarez; Mahtab Nourbakhsh

Автор: Scott Q. Harper
Название: RNA Interference Techniques
ISBN: 1493957627 ISBN-13(EAN): 9781493957620
Издательство: Springer
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Описание: This book presents methods for design and delivery of artificial inhibitory RNAs to neural tissue and for detecting or cloning endogenous microRNAs, used in research and in development of therapeutics for dominant genetic disorders, cancer, or viral infection.

Автор: Dagmar Wilhelm; Pascal Bernard
Название: Non-coding RNA and the Reproductive System
ISBN: 9401774153 ISBN-13(EAN): 9789401774154
Издательство: Springer
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Описание: This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract. The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.

Автор: Eckart Bindewald; Bruce A. Shapiro
Название: RNA Nanostructures
ISBN: 1493971379 ISBN-13(EAN): 9781493971374
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This volume presents a collection of computational and experimental protocols pertaining to the creation, characterization, and utilization of RNA nanostructures.

Автор: M. Lucrecia Alvarez; Mahtab Nourbakhsh
Название: RNA Mapping
ISBN: 1493910612 ISBN-13(EAN): 9781493910618
Издательство: Springer
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Цена: 22359.00 р.
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Описание: In RNA Mapping- Methods and Protocols expert researchers in the field detail many of the methods which are now commonly used to study RNA.

Автор: Graeme L. Conn
Название: Recombinant and In Vitro RNA Synthesis
ISBN: 1493958305 ISBN-13(EAN): 9781493958306
Издательство: Springer
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Описание: Part of Springer`s Methods in Molecular Biology series, this collection of detailed protocols guides the reader from the start of a new RNA project to the final sample, with step-by-step protocols and expert tips on deploying catalytic RNAs in the laboratory.

Автор: Daniel R. Perez
Название: Reverse Genetics of RNA Viruses
ISBN: 1493969625 ISBN-13(EAN): 9781493969623
Издательство: Springer
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Описание:

1. Reverse Genetics for Mammalian Orthoreovirus

Автор: Volker A. Erdmann; Stefan Jurga; Jan Barciszewski
Название: RNA and DNA Diagnostics
ISBN: 3319173049 ISBN-13(EAN): 9783319173047
Издательство: Springer
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Цена: 20962.00 р.
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Описание: The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman’s famous statement “What I cannot create, I do not understand.”

Автор: Frank J. Schmidt
Название: RNA-RNA Interactions
ISBN: 1493918958 ISBN-13(EAN): 9781493918959
Издательство: Springer
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Цена: 15372.00 р.
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Описание:

In this volume expert researchers in the field detail many of the methods which are now commonly used to study RNA. These methods are presented as a guidebook to scientists who are experienced with RNA research and want to brush up on a new technique. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Thorough and intuitive, RNA-RNA Interactions: Methods and Protocols guides scientists investigating biological systems and studying RNA.

Автор: Alexandra Lusser
Название: RNA Methylation
ISBN: 149396805X ISBN-13(EAN): 9781493968053
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This volume provides a comprehensive collection of current methods and protocols to study posttranscriptional base modifications in RNA with special focus on methylation.

Автор: Henrik Nielsen
Название: RNA
ISBN: 1493956434 ISBN-13(EAN): 9781493956432
Издательство: Springer
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Цена: 18167.00 р.
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Описание: In RNA: Methods and Protocols, expert researchers provide the procedures and methods used to describe the structure of messenger RNAs and non-coding RNAs that are transcribed by RNA polymerase II as the immediate gene products in mammalian cells.

Автор: Mouldy Sioud
Название: RNA Interference
ISBN: 1493915371 ISBN-13(EAN): 9781493915378
Издательство: Springer
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Описание: RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA`s unwanted effects.

Автор: Jane Y. Wu
Название: RNA and Cancer
ISBN: 3642444857 ISBN-13(EAN): 9783642444852
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Accumulating evidence supports the role of defects in post-transcriptional gene regulation in the development of cancer. RNA and Cancer examines the recent advances in our understanding of post-transcriptional gene regulation, especially RNA processing and its role in cancer development and treatment. A particular focus is mRNA splicing, but other topics such as microRNAs, mRNA stability, the perinucleolar compartment, and oligonucleotide therapeutics are also covered in detail. All chapters have been written by internationally renowned experts. The book is intended for all with an interest in gene regulation and cancer biology, and especially for those not directly working on RNA biology, including clinicians and medical students. It is hoped that it will stimulate further innovative research collaborations between RNA biologists and cancer researchers to the benefit of patients.