RNA Mapping, M. Lucrecia Alvarez; Mahtab Nourbakhsh

Автор: M. Lucrecia Alvarez; Mahtab Nourbakhsh
Название: RNA Mapping
ISBN: 1493953869 ISBN-13(EAN): 9781493953868
Издательство: Springer
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Описание: In RNA Mapping- Methods and Protocols expert researchers in the field detail many of the methods which are now commonly used to study RNA.

Автор: Scott Q. Harper
Название: RNA Interference Techniques
ISBN: 1493957627 ISBN-13(EAN): 9781493957620
Издательство: Springer
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Описание: This book presents methods for design and delivery of artificial inhibitory RNAs to neural tissue and for detecting or cloning endogenous microRNAs, used in research and in development of therapeutics for dominant genetic disorders, cancer, or viral infection.

Автор: Volker A. Erdmann; Stefan Jurga; Jan Barciszewski
Название: RNA and DNA Diagnostics
ISBN: 3319173049 ISBN-13(EAN): 9783319173047
Издательство: Springer
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Цена: 20962.00 р.
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Описание: The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman’s famous statement “What I cannot create, I do not understand.”

Автор: Dagmar Wilhelm; Pascal Bernard
Название: Non-coding RNA and the Reproductive System
ISBN: 9401774153 ISBN-13(EAN): 9789401774154
Издательство: Springer
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Описание: This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract. The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.

Автор: Mouldy Sioud
Название: RNA Interference
ISBN: 1493915371 ISBN-13(EAN): 9781493915378
Издательство: Springer
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Описание: RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA`s unwanted effects.

Автор: Frank J. Schmidt
Название: RNA-RNA Interactions
ISBN: 1493918958 ISBN-13(EAN): 9781493918959
Издательство: Springer
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Цена: 15372.00 р.
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Описание:

In this volume expert researchers in the field detail many of the methods which are now commonly used to study RNA. These methods are presented as a guidebook to scientists who are experienced with RNA research and want to brush up on a new technique. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Thorough and intuitive, RNA-RNA Interactions: Methods and Protocols guides scientists investigating biological systems and studying RNA.

Автор: Daniel R. Perez
Название: Reverse Genetics of RNA Viruses
ISBN: 1493969625 ISBN-13(EAN): 9781493969623
Издательство: Springer
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Описание:

1. Reverse Genetics for Mammalian Orthoreovirus

Автор: Christina Waldsich
Название: RNA Folding
ISBN: 149396058X ISBN-13(EAN): 9781493960583
Издательство: Springer
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Описание: Focusing on in vitro and intracellular RNA structure formation, RNA Folding: Methods and Protocols provides a comprehensive collection of experimental protocols which are suitable to dissect RNA folding pathways and to characterize the structure of RNA folding intermediates at nucleotide or even atomic resolution.

Автор: Peter M. Rabinovich
Название: Synthetic Messenger RNA and Cell Metabolism Modulation
ISBN: 1493959670 ISBN-13(EAN): 9781493959679
Издательство: Springer
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Цена: 20263.00 р.
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Описание: This Methods in Molecular Biology (TM) book covers mRNA synthesis, modifications and delivery, offering protocols, material lists and practical tips along with examples of cell reprogramming and analysis in the fields of immunotherapy and stem cell research.

Автор: Kenneth C. Keiler
Название: Bacterial Regulatory RNA
ISBN: 1493959417 ISBN-13(EAN): 9781493959419
Издательство: Springer
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Описание: This Methods in Molecular Biology (TM) volume covers methods and techniques to identify regulatory RNAs, characterizing the function and expression of regulatory RNAs in bacterial cells, RNA structure prediction and interaction between regulatory RNAs and proteins.

Автор: Alexandra Lusser
Название: RNA Methylation
ISBN: 149396805X ISBN-13(EAN): 9781493968053
Издательство: Springer
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Описание: This volume provides a comprehensive collection of current methods and protocols to study posttranscriptional base modifications in RNA with special focus on methylation.

Автор: Graeme L. Conn
Название: Recombinant and In Vitro RNA Synthesis
ISBN: 1493958305 ISBN-13(EAN): 9781493958306
Издательство: Springer
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Описание: Part of Springer`s Methods in Molecular Biology series, this collection of detailed protocols guides the reader from the start of a new RNA project to the final sample, with step-by-step protocols and expert tips on deploying catalytic RNAs in the laboratory.