RNA, Henrik Nielsen

Автор: M. Lucrecia Alvarez; Mahtab Nourbakhsh
Название: RNA Mapping
ISBN: 1493953869 ISBN-13(EAN): 9781493953868
Издательство: Springer
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Описание: In RNA Mapping- Methods and Protocols expert researchers in the field detail many of the methods which are now commonly used to study RNA.

Автор: Ane Sesma; Tobias von der Haar
Название: Fungal RNA Biology
ISBN: 3319350110 ISBN-13(EAN): 9783319350110
Издательство: Springer
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Описание: RNA polymerase II-dependent transcription in fungi and its interplay with mRNA decay.- Pre-mRNA splicing and the spliceosome: assembly, catalysis and fidelity.- Fungal pre-mRNA 3' end processing.- mRNA export.- mRNA translation: Fungal variations on a eukaryotic theme.- mRNA localization.- mRNA degradation and decay.- Cytoplasmic mRNA surveillance pathways.- Making Ribosomes: pre-rRNA Transcription and Processing.- Biogenesis and evolution of functional tRNAs.- Small RNA-mediated gene silencing in Neurospora.- The RNAi machinery in Mucorales: the emerging role of endogenous small RNAs.- Regulation of pericentric heterochromatin by ncRNA in Schizosaccharomyces pombe.- Approaches for dissecting RNA-binding protein networks.- Bioinformatic tools for Next-Generation RNA sequencing analysis.

Автор: Volker A. Erdmann; Jan Barciszewski
Название: DNA and RNA Nanobiotechnologies in Medicine: Diagnosis and Treatment of Diseases
ISBN: 3642443524 ISBN-13(EAN): 9783642443527
Издательство: Springer
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Описание: This book covers the design and synthesis of DNA and RNA nanostructures with the aim of using them for drug deliveries, for genetic immunization, for metabolite and nucleic acid detection, gene regulation, and siRNA delivery for cancer treatment.

Автор: Jane Y. Wu
Название: RNA and Cancer
ISBN: 3642444857 ISBN-13(EAN): 9783642444852
Издательство: Springer
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Описание: Accumulating evidence supports the role of defects in post-transcriptional gene regulation in the development of cancer. RNA and Cancer examines the recent advances in our understanding of post-transcriptional gene regulation, especially RNA processing and its role in cancer development and treatment. A particular focus is mRNA splicing, but other topics such as microRNAs, mRNA stability, the perinucleolar compartment, and oligonucleotide therapeutics are also covered in detail. All chapters have been written by internationally renowned experts. The book is intended for all with an interest in gene regulation and cancer biology, and especially for those not directly working on RNA biology, including clinicians and medical students. It is hoped that it will stimulate further innovative research collaborations between RNA biologists and cancer researchers to the benefit of patients.

Автор: Zdravka Medarova
Название: RNA Imaging
ISBN: 1493931474 ISBN-13(EAN): 9781493931477
Издательство: Springer
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Описание: This detailed volume will focus on the phenomenon of RNA interference by providing comprehensive coverage of various techniques for in vivo micro/siRNA imaging including the design and synthesis of specific imaging agents and tools, the development of imaging methodologies, and their interpretation.

Автор: Volker A. Erdmann; Stefan Jurga; Jan Barciszewski
Название: RNA and DNA Diagnostics
ISBN: 3319361996 ISBN-13(EAN): 9783319361994
Издательство: Springer
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Описание: The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease.

Автор: Frank J. Schmidt
Название: RNA-RNA Interactions
ISBN: 1493941615 ISBN-13(EAN): 9781493941612
Издательство: Springer
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Описание:

1. Identifying RNA Recombination Events and Non-covalent RNA-RNA Interactions with the Molecular Colony Technique

Helena V. Chetverina and Alexander B. Chetverin

2. RNA-directed Recombination of RNA in Vitro

Niles Lehman, Nilesh Vaidya, and Jessica A. M. Yeates

3. RNA-RNA Selex

B. Cho

4. Identification of Antisense RNA S0tem-loops that Inhibit RNA-protein Interactions using a Bacterial Reporter System

Kazuo Harada

5. Trans-activation of Large Ribozymes

Matthew B. Martin, Thomas L. Leeper, and Frank J. Schmidt

6. Native Purification and Labeling of RNA for Single Molecule Fluorescence Studies

Arlie J. Rinaldi, Krishna C. Suddala, and Nils G. Walter

7. Single Molecule Studies of RNA-RNA Interactions

Dongmei Yu, Peiwu Qin, and Peter V. Cornish

8. Modification Interference Analysis of the Ribosome

Simpson Joseph

9. Assessing Intermolecular RNA: RNA Interactions Within a Ribonucleoprotein Complex Using Heavy Metal Cleavage Mapping

Keith T. Gagnon and E. Stuart Maxwell

10. Monitoring RNA-RNA Interactions With Electrophoretic Mobility Shift Assays: Analysis Of Trna Binding To The T Box Riboswitch Antiterminator RNA

R. Anupam, S. Zhou, and J.V. Hines

11. Electrophoretic Mobility Shift Assay of RNA-RNA Complexes

Geunu Bak, Kook Han, Kwang-sun Kim, and Younghoon Lee

12. Structural Studies of a Double-stranded RNA from Trypanosome RNA Editing by

Small Angle X-ray Scattering

Angela Criswell and Blaine H.M. Mooers

13. Fusion RNAs in Crystallographic Studies of Double-stranded RNA from

Trypanosome RNA Editing

Blaine H.M. Mooers

Автор: Hans-Joachim Anders; Adriana Migliorini
Название: Innate DNA and RNA Recognition
ISBN: 1493945831 ISBN-13(EAN): 9781493945832
Издательство: Springer
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Описание:

Part I: Analysis of Viral Nucleic Acid Sensing In-Silico and In-Vitro

1. Detection of RNA Modifications by HPLC Analysis and Competitive ELISA

Gernot Nees, Andreas Kaufmann and Stefan Bauer

2. Enzymatic Synthesis and Purification of a Defined RIG-I Ligand

Marion Goldeck, Martin Schlee, Gunther Hartmann, and Veit Hornung

3. Crystallization of Mouse RIG-I ATPase Domain: In situ Proteolysis

Filiz Civril and Karl-Peter Hopfner

4. Isolation of RIG-I-associated RNAs from Virus Infected Cells

Andreas Schmidt, Andreas Linder, Nicolas Linder, and Simon Rothenfu er

5. Structure Modeling of Toll-like Receptors

Jing Gong and Tiandi Wei

6. Nucleic Acid Recognition in Dendritic Cells

Alexander Heiseke, Katharina Eisenдcher, and Anne Krug

7. Viral Nucleic Acid Recognition in Human Non-immune cells: In vitro Systems

Andrea Ribeiro and Markus Wцrnle

8. Analysis of Nucleic Acid-induced Non-immune Cell Death in Vitro

Simone Romoli, Adriana Migliorini

9. In vitro Analysis of Nucleic Acid Recognition in B Lymphocytes

Saskia Ziegler and Isabelle Bekeredjian-Ding

10. Mapping of Optimal CD8 T Cell Epitopes

Julia Roider, Thomas Vollbrecht and Rika Draenert

11. A Modular Approach to Suppression Ass says: TLR-Ligands, Conditioned Medium, and Viral Infection

Viktor H. Koelzer and David Anz

Автор: Thomas Dandekar; P. Bengert; T. Dandekar; D. Ostar
Название: RNA Motifs and Regulatory Elements
ISBN: 364262586X ISBN-13(EAN): 9783642625862
Издательство: Springer
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Описание: RNA Motifs and Regulatory Elements is the new edition of the successful book, "Regulatory RNA".

Автор: Volker A. Erdmann; Jan Barciszewski
Название: RNA Technologies and Their Applications
ISBN: 3642264905 ISBN-13(EAN): 9783642264900
Издательство: Springer
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Описание: RNA technologies have the potential to revolutionize biomedical research and medicine. This book provides a state-of-the-art review concerning the molecular basis as well as applications of RNA based technologies in molecular biology and medicine.

Автор: Scott Q. Harper
Название: RNA Interference Techniques
ISBN: 1493957627 ISBN-13(EAN): 9781493957620
Издательство: Springer
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Описание: This book presents methods for design and delivery of artificial inhibitory RNAs to neural tissue and for detecting or cloning endogenous microRNAs, used in research and in development of therapeutics for dominant genetic disorders, cancer, or viral infection.

Автор: Marvin Jens
Название: Dissecting Regulatory Interactions of RNA and Protein
ISBN: 3319361171 ISBN-13(EAN): 9783319361178
Издательство: Springer
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Описание: The introduction presents post-transcriptional gene regulation from a distinct angle, highlighting aspects of information theory and evolution and laying the groundwork for the questions addressed in the subsequent chapters, which concern the regulation of the transcriptome as the primary functional carrier of active genetic information.