Описание: The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg`s well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited.
Автор: Donnelly Название: Environmental Health in Central and Eastern Europe ISBN: 9048172101 ISBN-13(EAN): 9789048172108 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents the latest research in quantifying complex mixtures in the environment and analyzing their potential impact on human health.
Автор: Randy L. Jirtle; Frederick L. Tyson Название: Environmental Epigenomics in Health and Disease ISBN: 3642368263 ISBN-13(EAN): 9783642368264 Издательство: Springer Рейтинг: Цена: 30039.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights the correlation between environmental exposure during early development, and diseases such as autism, addiction, neurological diseases, diabetes, obesity and cancer. Includes a chapter on the legal and ethical implications of epigenetics.
Автор: Randy L. Jirtle; Frederick L. Tyson Название: Environmental Epigenomics in Health and Disease ISBN: 3642435955 ISBN-13(EAN): 9783642435959 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs are established as stem cell differentiate during embryogenesis, and they are normally faithfully reproduced during mitosis. Moreover, they can also be maintained during meiosis, resulting in epigenetic transgenerational disease inheritance, and also potentially introducing phenotypic variation that is selected for in the evolution of new species. The objective of this two volume book is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular disease, diabetes, obesity, and schizophrenia later in life by modifying the epigenome. Consequently, epigenetic research promises to markedly improve our ability to diagnosis, prevent, and treat the pathological conditions of humans; however, it also introduces unique legal and ethical issues. This volume highlights the correlation between environmental factors and complex diseases, such as autism, addiction, neurological diseases, diabetes, obesity and cancer. It concludes with a chapter on legal and ethical implications of epigenetics.
Автор: Michail Ignatiadis; Christos Sotiriou; Klaus Pante Название: Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer ISBN: 364244587X ISBN-13(EAN): 9783642445873 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This important book provides up-to-date information on a series of topical issues relating to the approach to minimal residual disease in breast cancer patients. It first explains how the study of minimal residual disease and circulating and disseminated tumor cells (CTCs/DTCs) can assist in the understanding of breast cancer metastasis. A series of chapters then discuss the various technologies available for the detection and characterization of CTCs and DTCs, pinpointing their merits and limitations. Detailed consideration is given to the relevance of CTCs and DTCs, and their detection, to clinical research and practice. The role of other blood-based biomarkers is also addressed, and the closing chapters debate the challenges facing drug and biomarker co-development and the use of CTCs for companion diagnostic development. This book will be of interest and assistance to all who are engaged in the modern management of breast cancer.
Автор: Norbert H. Seemayer; Wolfgang Hadnagy Название: Environmental Hygiene II ISBN: 3642467148 ISBN-13(EAN): 9783642467141 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Furthermore, assessment of exposure to environmental and occupational chemicals in man are presented as well as epidemiological studies on the health effects by environmental pollution, studies of inhalation toxicology and strategies and policy of environmental control.
Автор: Polyxeni Nicolopoulou-Stamati; Luc Hens; Vyvyan C. Название: Cancer as an Environmental Disease ISBN: 1402020198 ISBN-13(EAN): 9781402020193 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Contains a number of chapters from specialists in the field who consider, from a number of different perspectives, the evidence that supports the environmental cancer aetiology hypothesis. This book presents an examination of the policy implications of accepting that the cancer epidemic may essentially be preventable.
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