Environmental Epigenomics in Health and Disease, Randy L. Jirtle; Frederick L. Tyson
Автор: Appasani Название: Epigenomics ISBN: 1107697832 ISBN-13(EAN): 9781107697836 Издательство: Cambridge Academ Рейтинг: Цена: 10138.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading experts from academia and both the biotechnology and pharmaceutical industries introduce the emerging field of epigenomics, covering a wide range of topics and methods such as basic chromatin biology, imprinting at genome-wide level, and the role of epigenomics in disease biology and epidemiology.
Автор: Charles Spillane; Peter C. McKeown Название: Plant Epigenetics and Epigenomics ISBN: 1493962299 ISBN-13(EAN): 9781493962297 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Many fundamental discoveries concerning epigenetics and the elucidation of mechanisms of epigenetic regulation have developed from studies performed in plants.
Описание: Proceedings of a NATO ARW held in Luso, Portugal, June 1-5, 1992
Автор: Randy L Jirtle; Frederick L. Tyson Название: Environmental Epigenomics in Health and Disease ISBN: 3642427286 ISBN-13(EAN): 9783642427282 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs are established as stem cell differentiate during embryogenesis, and they are normally faithfully reproduced during mitosis. Moreover, they can also be maintained during meiosis, resulting in epigenetic transgenerational disease inheritance, and also potentially introducing phenotypic variation that is selected for in the evolution of new species. The objective of this book is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular disease, diabetes, obesity, and schizophrenia later in life by modifying the epigenome.
Автор: Randy L. Jirtle; Frederick L. Tyson Название: Environmental Epigenomics in Health and Disease ISBN: 3642368263 ISBN-13(EAN): 9783642368264 Издательство: Springer Рейтинг: Цена: 30039.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights the correlation between environmental exposure during early development, and diseases such as autism, addiction, neurological diseases, diabetes, obesity and cancer. Includes a chapter on the legal and ethical implications of epigenetics.
Автор: Charles Spillane; Peter C. McKeown Название: Plant Epigenetics and Epigenomics ISBN: 1627037721 ISBN-13(EAN): 9781627037723 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Many fundamental discoveries concerning epigenetics and the elucidation of mechanisms of epigenetic regulation have developed from studies performed in plants.
Автор: Andrew E. Teschendorff Название: Computational and Statistical Epigenomics ISBN: 9401799261 ISBN-13(EAN): 9789401799263 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book introduces the reader to modern computational and statistical tools for translational epigenomics research. Over the last decade, epigenomics has emerged as a key area of molecular biology, epidemiology and genome medicine. Epigenomics not only offers us a deeper understanding of fundamental cellular biology, but also provides us with the basis for an improved understanding and management of complex diseases. From novel biomarkers for risk prediction, early detection, diagnosis and prognosis of common diseases, to novel therapeutic strategies, epigenomics is set to play a key role in the personalized medicine of the future. In this book we introduce the reader to some of the most important computational and statistical methods for analyzing epigenomic data, with a special focus on DNA methylation. Topics include normalization, correction for cellular heterogeneity, batch effects, clustering, supervised analysis and integrative methods for systems epigenomics. This book will be of interest to students and researchers in bioinformatics, biostatistics, biologists and clinicians alike. Dr. Andrew E. Teschendorff is Head of the Computational Systems Genomics Lab at the CAS-MPG Partner Institute for Computational Biology, Shanghai, China, as well as an Honorary Research Fellow at the UCL Cancer Institute, University College London, UK.
Описание: Proceedings of a NATO ARW held in Luso, Portugal, June 1-5, 1992
Автор: Polyxeni Nicolopoulou-Stamati; Luc Hens; Vyvyan C. Название: Cancer as an Environmental Disease ISBN: 1402020201 ISBN-13(EAN): 9781402020209 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: - Controversial topic because many of the proposed solutions or policies may damage the economy in the short term in order to reap health benefits which will only become apparent several decades in the future- Each chapter is written by experts in the field throughout the world
Автор: Polyxeni Nicolopoulou-Stamati; Luc Hens; Vyvyan C. Название: Cancer as an Environmental Disease ISBN: 1402020198 ISBN-13(EAN): 9781402020193 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Contains a number of chapters from specialists in the field who consider, from a number of different perspectives, the evidence that supports the environmental cancer aetiology hypothesis. This book presents an examination of the policy implications of accepting that the cancer epidemic may essentially be preventable.
Автор: W. Bruce Campbell; Silvia L?pez-Ort?z Название: Sustainable Food Production Includes Human and Environmental Health ISBN: 9402407545 ISBN-13(EAN): 9789402407549 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With concise reviews of the key issues in agroecology, this book identifies the complex problems that must be tackled in order to progress towards improved sustainability in food production. If features the work of many of the leading authorities in the field.
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