Immunotherapy of Renal Cell Carcinoma, R.J.A. van Moorselaar; Frans M.J. Debruyne; Ronald
Автор: Tim F. Greten Название: Immunotherapy of Hepatocellular Carcinoma ISBN: 3319649574 ISBN-13(EAN): 9783319649573 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma.
Автор: Yotnda Название: Immunotherapy of Cancer ISBN: 1607617854 ISBN-13(EAN): 9781607617853 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes detailed procedures for trainees and experts in the area of basic, clinical science who wish to undertake their own cutting-edge immunotherapy studies. It includes coverage of pre-clinical models for cancer immunotherapy.
Автор: Ludewig Burkhard, Hoffmann Matthias W. Название: Adoptive Immunotherapy / Methods and Protocols ISBN: 1588294064 ISBN-13(EAN): 9781588294067 Издательство: Springer Рейтинг: Цена: 24456.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An authoritative collection of optimal techniques for producing and characterizing the immunologically active cells and effector molecules now gaining wide use in the clinical treatment of patients. Taking advantage of the latest technologies, the authors present readily reproducible experimental protocols for the study of dendritic cells, T cells, monoclonal antibodies, and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on the progress of selected approaches in clinical trials. Additional chapters cover the molecular definition of target antigens, mathematical modeling approaches to immunotherapy, and the utilization of regulatory T cells. The protocols make it possible to study the adoptive transfer of tailored antigen-specific immune cells and to improve the clinical application of adoptive immunotherapy.
Автор: Dranoff Название: Cancer Immunology and Immunotherapy ISBN: 3642141358 ISBN-13(EAN): 9783642141355 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Автор: George C. Prendergast Название: Cancer Immunotherapy, ISBN: 0123942969 ISBN-13(EAN): 9780123942968 Издательство: Elsevier Science Рейтинг: Цена: 16169.00 р. Наличие на складе: Поставка под заказ.
Описание: There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles.
Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.
The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
Автор: Lockey / Ledford Название: Allergens and Allergen Immunotherapy, Fourth Edition ISBN: 1420061976 ISBN-13(EAN): 9781420061970 Издательство: Informa Рейтинг: Цена: 20970.00 р. Наличие на складе: Нет в наличии.
Описание: Compiling the research of an influential team of investigators and scientists, Allergens and Allergen Immunotherapy is filled with quick reference charts, tables and indexes. Allergists, immunologists, and otolaryngologists will find this new streamlined fourth edition a great practical reference for on-the-go diagnosis, treatment, and management of allergies.
Автор: Alec Sehon; Kent T. HayGlass; Dietrich Kraft Название: New Horizons in Allergy Immunotherapy ISBN: 146137684X ISBN-13(EAN): 9781461376842 Издательство: Springer Рейтинг: Цена: 11878.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the First International Rushmore Conference held in Rapid City, South Dakota, September 28-30, 1995
Автор: Jeffrey M. Jacobson Название: Immunotherapy for Infectious Diseases ISBN: 1468496816 ISBN-13(EAN): 9781468496819 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The contributors synthesize the principles of immune defense on the molecular level (monoclonal antibodies, vaccines, methods of antigen presentation, and cytokines and cytokine antagonists), as well as on the cellular and clinical levels levels as a protection against infection.
Автор: Frederick Becker Название: Radiotherapy, Surgery, and Immunotherapy ISBN: 1468427415 ISBN-13(EAN): 9781468427417 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The history of the development of cancer therapy has been marked by a recurring pattern, one of initially exciting and encouraging results as new methods were introduced, followed by dismaying failures.
Автор: Tyler J. Curiel Название: Cancer Immunotherapy ISBN: 1489993436 ISBN-13(EAN): 9781489993434 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This work offers a historical perspective on tumor immunotherapy, discusses fundamental mechanisms of failed tumor rejection, looks at passive strategies to boost anti-tumor immunity, and details active strategies to boost anti-tumor immunity.
Автор: James H. Finke; Ronald M. Bukowski Название: Cancer Immunotherapy at the Crossroads ISBN: 1468498444 ISBN-13(EAN): 9781468498448 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading investigators and clinicians detail the different mechanisms used by tumors to escape and impair the immune system and then spell out possible clinical strategies to prevent or reverse tumor-induced immune dysfunction.
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