Profiling the European Citizen, Mireille Hildebrandt; Serge Gutwirth
Автор: J?rg Epplen; Thomas Lubjuhnn Название: DNA Profiling and DNA Fingerprinting ISBN: 3764360186 ISBN-13(EAN): 9783764360184 Издательство: Springer Рейтинг: Цена: 13060.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text reflects practical approaches to answering a variety of biological and medical questions, using DNA fingerprinting and genetic profiling in a broad sense that also includes statistical evaluation of the data. The book is aimed at students as well as academic teachers and researchers.
Автор: Robert Gr?tzmann; Christian Pilarsky Название: Cancer Gene Profiling ISBN: 1493932039 ISBN-13(EAN): 9781493932030 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cancer Gene Profiling
Автор: Virginia Espina Название: Molecular Profiling ISBN: 1493969897 ISBN-13(EAN): 9781493969890 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Tumor Staging and Grading: A Primer
Stacy M. Telloni
2. Innovations in Clinical Trial Design in the Era of Molecular Profiling
Julia D. Wulfkuhle, Alexander Spira, Kirsten H. Edmiston, and Emanuel F. Petricoin
3. Personalized Medicine: Ethical Aspects
G. Terry Sharrer 4. Antibody Validation by Western Blotting
Michele Signore, Valeria Manganelli and Alex Hodge
5. Scanning Electron Microscopy Sample Preparation and Imaging
Jenny Ngoc Tran Nguyen and Amanda M. Harbison
Claudius Mueller, Michael G. Harpole, and Virginia Espina
7. Application of Hydrogel Nanoparticles for the Capture, Concentration, and Preservation of Low-Abundance Biomarkers
Ruben Magni and Alessandra Luchini
8. Using Laser Capture Microdissection to Isolate Cortical Laminae in Non-human Primate Brain
Brian A. Corgiatand Claudius Mueller
9. Western Blot Techniques
Brianna Kim
10. ELISA for Monitoring Nerve Growth Factor
Justin B. Davis
11. Reverse Phase Protein Microarrays
Elisa Baldelli, Valerie Calvert, Alex Hodge, Amy VanMeter, Emanuel F. Petricoin III, and Mariaelena Pierobon
12. Clustering and Network Analysis of Reverse-Phase Protein Array Data
Adam Byron
13. PCR: Identification of Genetic Polymorphisms
Amanda M. Harbison and Jenny Ngoc Tran Nguyen
14. Microsatellite Analysis for Identification of Individuals Using Bone from the Extinct Steller's Sea Cow (Hydrodamalis gigas)
Jeffery F. Warner, Michael G. Harpole, and Lorelei D. Crerar
15. Somatic DNA Mutation Analysis
Anthony O'Grady and Robert Cummins
16. Optimization of Immunostaining for Prospective Image Analysis
Scott M. Lawrence and Yelena G. Golubeva
17. Fluorescence in situ Hybridization of Cells, Chromosomes, and Formalin Fixed Paraffin Embedded Tissues
Ahmad Alamri, Jun Yeb Nam, and Jan K. Blancato
18. High-Resolution Image Stitching as a Tool to Assess Tissue-Level Protein Distribution and Localization
Bryan A. Millis and Matthew J. Tyska
19. Mass Spectrometry Based Biomarker Discovery
Weidong Zhou, Emanuel F. Petricoin III, and Caterina Longo
20. Quantitative Mass Spectrometry by Isotope-Dilution and Multiple Reaction Monitoring (MRM)
Paul Russo, Brian L. Hood, Nicholas W. Bateman, Thomas P. Conrads
21. LC-Mass Spectrometry for Metabolomics Allyson L. Dailey
22. Metabolomic Bioinformatic Analysis
Allyson L. Dailey
23. Stable Isotope Quantitative N-glycan Analysis by Liquid Separation Techniques and Mass Spectrometry
Stefan Mittermayr, Simone Albrecht, Csaba Vбradi, Silvia Millбn-Martнn, and Jonathan Bones
24. Grant Writing Tips for Translational Research
Lindsay Wescott, Michael Laskofski, Donna Senator, and Carly Curran
25. Inventions and Patents: A Practical Tutorial
Hina Mehta, Lille Tidwell, and Lance A. Liotta
26. Product Development and Commercialization of Diagnostic or Life Science Products for Scientists and Researchers
Meghan M. Alonso
Автор: Rani Название: MicroRNA Profiling ISBN: 1493965220 ISBN-13(EAN): 9781493965229 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume includes comprehensive descriptions of miRNA biogenesis and their role in the development and progression of various human diseases. The first few chapters of MicroRNA Profiling: Methods and Protocols discuss the effects of over-expressing and repressing of a target miRNA and their effects on cell viability and proliferation. The next few chapters explore the protocols for total RNA isolation from cells and cell-derived product including formalin fixed paraffin embedded tissue and plant tissue. The last few chapters discuss isolation and characterization of exosomes from medium conditioned by cell lines, serum, and plasma specimens. This book also includes discussions of several software tools, such as miRandola, PicTar, DIANA, and miRWalk. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, MicroRNA Profiling: Methods and Protocols is a valuable resource for anyone interested in the field of Micro RNAs.
Автор: Mathias Munschauer Название: High-Resolution Profiling of Protein-RNA Interactions ISBN: 3319368486 ISBN-13(EAN): 9783319368481 Издательство: Springer Рейтинг: Цена: 14365.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book describes how the study of a single RNA-binding protein and its interaction sites led to the development of the novel `protein occupancy profiling` technology that for the first time captured the mRNA sequence space contacted by the ensemble of expressed RNA binders.
Автор: Hicham Zegzouti; Said A. Goueli Название: Kinase Screening and Profiling ISBN: 1493949233 ISBN-13(EAN): 9781493949236 Издательство: Springer Рейтинг: Цена: 13275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. HTRF Kinase Assay Development and Methods in Inhibitor Characterization Yong Jia, Mari Manuia, and Jose Juarez
2. Application of Eukaryotic Elongation Factor-2 Kinase (eEF-2K) for Cancer Therapy: Expression, Purification, and High-Throughput Inhibitor Screening Clint D. J. Tavares, Ashwini K. Devkota, Kevin N. Dalby, and Eun Jeong Cho 3. Recombinant Kinase Production and Fragment Screening by NMR Spectroscopy Byeonggu Han and Hee-Chul Ahn 4. Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase and PI5P4Kα Lipid Kinase Mindy I. Davis, Douglas S. Auld, and James Inglese 5. Using Bioluminescent Kinase Profiling Strips to Identify Kinase Inhibitor Selectivity and Promiscuity Hicham Zegzouti, Jacquelyn Hennek, and Said A. Goueli 6. Measuring Activity of Phosphoinositide Lipid Kinases Using a Bioluminescent ADP-Detecting Assay Andrew W. Tai and Jolanta Vidugiriene
7. A High-Throughput Radiometric Kinase Assay Krisna C. Duong-Ly and Jeffrey R. Peterson 8. A High Content Assay to Screen for Modulators of EGFR Function Christophe Antczak and Hakim Djaballah 9. Monitoring Protein Kinase Expression and Phosphorylation in Cell Lysates with Antibody Microarrays Hong Zhang, Xiaoqing Shi, and Steven Pelech
10. From Enzyme to Whole Blood: Sequential Screening Procedure for Identification and Evaluation of p38 MAPK Inhibitors Silke M. Bauer, Jakub M. Kubiak, Ulrich Rothbauer, and Stefan Laufer
11. Genetically Encoded Fluorescent Indicators to Visualize Protein Phosphorylation in Living Cells Moritoshi Sato and Yoshio Umezawa
12. Characterization of an Engineered Src Kinase to Study Src Signaling and Biology Leanna R. Gentry, Andrei V. Karginov, Klaus M. Hahn, and Channing J. Der
13. Screening One-Bead-One-Compound Peptide Libraries for Optimal Kinase Substrates Thi B. Trinh and Dehua Pei
14. Determination of the Substrate Specificity of Protein Kinases with Peptide Micro- and Macroarrays Shenshen Lai, Dirk F.H. Winkler, Hong Zhang, and Steven Pelech 15. Rapid Identification of Protein Kinase Phosphorylation Site Motifs Using Combinatorial Peptide Libraries Chad J. Miller and Benjamin E. Turk
Автор: Thomas O. Metz Название: Metabolic Profiling ISBN: 149395816X ISBN-13(EAN): 9781493958160 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents protocols that are illustrative of the evolution of metabolic profiling from single molecule analysis to global metabolome profiling. It features cutting-edge protocols, presented from the perspective of leading experts in the field.
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