Автор: Anton Posch Название: Proteomic Profiling ISBN: 1493925490 ISBN-13(EAN): 9781493925490 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume presents the latest developments of the main pillars of protein analysis, such as sample preparation, separation and characterization. The book begins by describing basic but important sample preparation protocols. It then goes on to describe more sophisticated procedures on enriching specific protein classes and concludes with detailed descriptions of integrated work-flows for comprehensive protein analysis and characterization. The authors of the individual chapters are renowned protein biochemists who have all set value to provide a detailed representation of their lab work. Throughout the chapters, these authors share important tips and tricks for a successful and reproducible employment of their protocols in other laboratories. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Proteomic Profiling: Methods and Protocols is the perfect guide for students of Biochemistry, Biomedicine, Biology, and Genomics and will be an invaluable source for the experienced, practicing scientists.
Автор: Gary B. Smejkal and Alexander Lazarev Название: Separation Methods In Proteomics ISBN: 0824726995 ISBN-13(EAN): 9780824726997 Издательство: Taylor&Francis Рейтинг: Цена: 33686.00 р. Наличие на складе: Поставка под заказ.
Описание: Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular
applications, and adapt to user preferences in the analysis of proteins. "Separation Methods in Proteomics" provides a comprehensive examination of all major separation techniques for
proteomics research. Written as a compilation of hands-on methods exemplified by the work of several recognized leaders in the field, this book may serve as a guide for selection of the
optimal separation strategies to solve particular biological problems.
Recent progress in the development of robust analytical techniques and instrumentation has created the
need for good quality biological samples that are subject to analysis.Emphasizing the importance of sample preparation, the book explains how proteomes can be divided into smaller,
less complicated 'subproteomes' for individual analysis. It also highlights several hybrid approaches that take into account protein interactions. Including applications of the separation
methods currently employed in proteomic analyses for both clinical and basic research, "Separation Methods in Proteomics" contains practical information that can enhance the current
and future endeavors of scientists in proteomics, genomics, transcriptomics, biomarker discovery, and drug discovery.
Автор: Nedelkov Dobrin, Nelson Randall W. Название: New and Emerging Proteomic Techniques ISBN: 1588295192 ISBN-13(EAN): 9781588295194 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading researchers and innovators describe in step-by-step detail the latest techniques that promise to significantly impact the practice of proteomics, as well as its success in developing novel clinical agents. The methods span the entire spectrum of top-down and bottom-up approaches, including microarrays, gels, chromatography, and affinity separations, and address every aspect of the human proteome, both quantitatively and qualitatively. The techniques of protein detection utilized are diverse and range from fluorescence and resonance light scattering to surface plasmon resonance and mass spectrometry. The protocols follow the successful Methods in Molecular Biologyв„ў series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Описание: This volume is the first collection of applications of proteomics to analyze various human body fluids. Proteomics of Human Bodyfluids consists of two parts: the first provides basic principles and strategies for proteomic analysis of human body fluids, while the second offers more details regarding methodologies and recent findings and clinical applications of each specific type of human body fluids.
Автор: Katrin Marcus Название: Quantitative Methods in Proteomics ISBN: 1493958682 ISBN-13(EAN): 9781493958689 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) book surveys the principles of modern protein analysis, from statistical issues when planning proteomics experiments, to gel-based and mass spectrometry-based applications. Covers existing methods, software and data analysis.
Автор: Paul C. Guest Название: Proteomic Methods in Neuropsychiatric Research ISBN: 331952478X ISBN-13(EAN): 9783319524788 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies.
Автор: Pawel Ciborowski Название: Proteomic Profiling and Analytical Chemistry ISBN: 0444636889 ISBN-13(EAN): 9780444636881 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"Proteomic Profiling and Analytical Chemistry: The Crossroads, Second Edition" helps scientists without a strong background in analytical chemistry to understand principles of the multistep proteomic experiment necessary for its successful completion. It also helps researchers who do have an analytical chemistry background to break into the proteomics field. Highlighting points of junction between proteomics and analytical chemistry, this resource links experimental design with analytical measurements, data analysis, and quality control. This targeted point of view will help both biologists and chemists to better understand all components of a complex proteomic study.
The book provides detailed coverage of experimental aspects such as sample preparation, protein extraction and precipitation, gel electrophoresis, microarrays, dynamics of fluorescent dyes, and more. The key feature of this book is a direct link between multistep proteomic strategy and quality control routinely applied in analytical chemistry. This second edition features a new chapter on SWATH-MS, substantial updates to all chapters, including proteomic database search and analytical quantification, expanded discussion of post-hoc statistical tests, and additional content on validation in proteomics. Covers the analytical consequences of protein and peptide modifications that may have a profound effect on how and what researchers actually measureIncludes practical examples illustrating the importance of problems in quantitation and validation of biomarkersHelps in designing and executing proteomic experiments with sound analytics
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