Автор: Matthiesen Rune Название: Mass Spectrometry Data Analysis in Proteomics ISBN: 158829563X ISBN-13(EAN): 9781588295637 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aims to support researchers in deciding which programs to use in various tasks related to analysis of mass spectrometry data in proteomics. This work covers chapters that give a description of the theoretical background of each topic followed by descriptions of programs and the parameters best suited for different cases.
Автор: Agarwal Название: Proteomics in Human Reproduction ISBN: 3319484168 ISBN-13(EAN): 9783319484167 Издательство: Springer Рейтинг: Цена: 7685.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Brief explores the use of proteomics as a tool for biomarker discovery in human reproduction and summarizes current findings and trends of proteomic studies in both male and female infertility. This simplifies this important but complex topic and equips the novice reader with sufficient background information on the use of proteomics in human reproduction. The up-to-date scenario on proteomic investigations will also appeal to researchers and post graduate students looking to keep abreast with the latest developments in reproductive research. This review summarizes current findings of contemporary proteomic studies on infertility in both males and females with various reproductive pathologies, and its use in predicting the outcome of assisted reproduction. In human reproduction, the search for biomarkers via proteomics is a fast-evolving approach that involves the analysis of proteins in the reproductive tissues and fluids, such as the male gametes, seminal plasma, ovarian and endometrial tissue, and follicular and uterine fluid. By comparing the protein profile of a healthy, fertile individual against that of an infertile individual, the differentially expressed proteins may give an indication to certain proteins that could serve as useful biomarkers that are related to infertility. As proteomic studies continue to unravel the dynamic proteome behind various infertility conditions, there is potential for the discovery of prognostic markers that could ultimately help in both natural and assisted human reproduction.
Автор: Bostjan Kobe; Mitchell Guss; Thomas Huber Название: Structural Proteomics ISBN: 1617377899 ISBN-13(EAN): 9781617377891 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume includes chapters describing, in-depth, the individual steps in the Structural Genomics pipeline, as well as less detailed overviews of individual Structural Genomics initiatives.
Автор: Maryam Sarwat; Altaf Ahmad; M. Z. Abdin; M. Ibrahi Название: Stress Signaling in Plants: Genomics and Proteomics Perspective, Volume 2 ISBN: 3319421824 ISBN-13(EAN): 9783319421827 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This two-volume set takes an in-depth look at stress signaling in plants from a uniquely genomic and proteomic perspective and offers a comprehensive treatise that covers all of the signaling pathways and mechanisms that have been researched so far.
Автор: Toldr? Название: Proteomics in Foods ISBN: 1461456258 ISBN-13(EAN): 9781461456254 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book covers the principles of proteomics and details applications to foods, such as quality issues related with post-mortem processes in animal foods, identification of proteins, and safety issues like food authenticity and detection of animal species.
Описание: Biological processes involving large macromolecular assemblies are thought to be a dynamic consequence of cooperativity and metastability. The folding of a
peptide chain creates local environments from which "activity" can emerge. In the same way, the assembly of large molecular complexes creates dynamic features that would only be
feasible in a large construct.
The biological implications of such adaptation will be explored as it applies to the static quasisymmetry situations, as well as to the dynamics of
structural transitions. The current wealth of solved high-resolution complex structures makes this an appropriate time to summarize the state of the art in structural dynamics of living
architectures. With contributions by leading scientists in the fields of virology, bacterial flagellum, cytoskeleton, ribosome and giant enzymes, this work presents knowledge in the various
fields of structural proteomics of very large molecular assemblies, with focus on their mechanisms of action.
Автор: Louise von Stechow Название: Phospho-Proteomics ISBN: 1493950010 ISBN-13(EAN): 9781493950010 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Part I: Techniques for Tagging Phospho-Moieties
1. Thiol-ene Enabled Detection of Thiophosphorylation as a Labeling Strategy for Phosphoproteins
Kaelyn E. Wilke and Erin E. Carlson
2. Phosphopeptide Detection with Biotin-Labeled Phos-tag
Emiko Kinoshita-Kikuta, Eiji Kinoshita and Tohru Koike
3. Phosphopeptide Enrichment by Covalent Chromatography after Solid Phase Derivatization of Protein Digests on Reversed Phase Supports
Heinz Nika, Ruth Hogue Angeletti, and David H. Hawke
Part II: Labeling Techniques for Quantitative Phosphoproteomics
4. Peptide Labeling Using Isobaric Tagging Reagents for Quantitative Phosphoproteomics
Lei Cheng, Trairak Pisitkun, Mark A. Knepper, and Jason D. Hoffert
5. Identification of Direct Kinase Substrates Using Analogue-Sensitive Alleles
Daniel A. Rothenberg, Elizabeth A. Gordon, Forest M. White, and Sebastian Lourido
6. Quantitative Analysis of Tissue Samples by Combining iTRAQ Isobaric Labeling with Selected/Multiple Reaction Monitoring (SRM/MRM)
Ryohei Narumi and Takeshi Tomonaga
Part III: Phosphopeptide Enrichment Strategies
7. Enrichment Strategies in Phosphoproteomics
Alexander Leitner
8. Phosphopeptide Enrichment by Immobilized Metal Affinity Chromatography
Tine E. Thingholm and Martin R. Larsen
9. The use of Titanium Dioxide for Selective Enrichment of Phosphorylated Peptides
Tine E. Thingholm and Martin R. Larsen
10. Sequential Elution from IMAC (SIMAC) - An Efficient Method for Enrichment and Separation of Mono- and Multi-Phosphorylated Peptides
Tine E. Thingholm and Martin R. Larsen
11. Improving the Phosphoproteome Coverage for Limited Sample Amounts Using TiO2-SIMAC-HILIC (TiSH) Phosphopeptide Enrichment and Fractionation
Kasper Engholm-Keller and Martin R. Larsen
12. Offline High pH Reversed-Phase Peptide Fractionation for Deep Phosphoproteome Coverage
Tanveer S Batth, Jesper V Olsen
13. Phosphopeptide Enrichment Using Various Magnetic Nanocomposites - An Overview
Нris L. Batalha and Ana Cecнlia A. Roque
Part IV: Phosphoprotein Analysis by Mass Spectrometry
14. Two Dimensional Gel Electrophoresis-Based Plant Phosphoproteomics
Chao Hanand Pingfang Yang
15. Variable Digestion Strategies for Phosphoproteomics Analysis
Humberto Gonczarowska-Jorge, Margherita Dell'Aica, Clarissa Dickhut, and Renй P. Zahedi
16. On-line LC-FAIMS-MS/MS for the Analysis of Phosphorylation in Proteins
Hongyan Zhao, Andrew J. Creese, and Helen J. Cooper
17. Simple and Reproducible Sample Preparation for Single Shot Phosphoproteomics With High Sensitivity
Rosa R. Jersie-Christensen, Abida Sultan, and Jesper V. Olsen
Part V: High-throughput Studies of the Phosphoproteome
18. Identification of Direct Kinase Substrates via Kinase Assay Linked Phosphoproteomics
Liang Xue, Justine V. Arrington, and W. Andy Tao
19. Phosphoprotein Detection by High-Throughput Flow Cytometry
Johannes Landskronand Kjetil Taskйn
Part VI: BioinformaticsResources for Phosphoproteomics Analyses
20. Resources for Assignment of Phosphorylation Sites on Peptides and Proteins
Vaishnavi Ravikumar, Boris Macek, and Ivan Mijakovic
21. From Phosphosites to Kinases
Stephanie Munk, Jan C. Refsgaard, and Jesper V. Olsen, and Lars J. Jensen
22. Search Databases and Statistics - Pitfalls
Название: Phospho-proteomics ISBN: 1493930486 ISBN-13(EAN): 9781493930487 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Rune Matthiesen Название: Mass Spectrometry Data Analysis in Proteomics ISBN: 1617376442 ISBN-13(EAN): 9781617376443 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is an in-depth guide to the theory and practice of analyzing raw mass spectrometry (MS) data in proteomics. General guidelines for data analysis using search engines such as Mascot, Xtandem, and VEMS are provided, with specific attention to identifying poor quality data and optimizing search parameters.
Автор: Gerard Drewes; Marcus Bantscheff Название: Chemical Proteomics ISBN: 1493958003 ISBN-13(EAN): 9781493958009 Издательство: Springer Рейтинг: Цена: 16070.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The multidisciplinary science of chemical proteomics studies how small molecules of synthetic or natural origin bind to proteins and modulate their function. In Chemical Proteomics: Methods and Protocols, expert researchers in the field provide key techniques to investigate chemical proteomics focusing on analytical strategies, how probes are generated, techniques for the discovery of small molecule targets and the probing of target function, and small molecule ligand and drug discovery. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Chemical Proteomics : Methods and Protocols seeks to provide methodologies that will contribute to a wider application of chemical proteomics methods in biochemical and cell biological laboratories.
Автор: Dariusz Leszczynski Название: Radiation Proteomics ISBN: 9400758952 ISBN-13(EAN): 9789400758957 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Methods of proteomics have been shown to be powerful tools in search of target proteins - proteins that respond in cells to an internal or an external stimulus. This book, by presenting the current status of the use of proteomics in radiation biology, will help to attract attention to the field of radiation proteomics.
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