Recombinant Antibodies for Cancer Therapy, Martin Welschof; J?rgen Krauss

Автор: Suresh C. Srivastava
Название: Radiolabeled Monoclonal Antibodies for Imaging and Therapy
ISBN: 1468455400 ISBN-13(EAN): 9781468455403
Издательство: Springer
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Описание: The advent of hybridoma technology leading to the successful produc- tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations.

Автор: Benjamin Bonavida
Название: Resistance to Immunotherapeutic Antibodies in Cancer
ISBN: 1461476534 ISBN-13(EAN): 9781461476535
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book examines antibody-mediated anti-cancer therapy, covering the use of mAbs against various cancers, developments in the molecular, biochemical and genetic mechanisms of resistance by various mAbs and novel mAbs to overcome drug and radition resistance.

Автор: David M. Goldenberg
Название: Cancer Imaging with Radiolabeled Antibodies
ISBN: 0792306317 ISBN-13(EAN): 9780792306313
Издательство: Springer
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Цена: 51570.00 р.
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Описание: It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription.

Автор: Mohammad Resa Nowrousian
Название: Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology
ISBN: 3709119049 ISBN-13(EAN): 9783709119044
Издательство: Springer
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Цена: 18167.00 р.
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Описание: In its Second Edition, this book covers anemia in cancer patients, and treatment with Recombinant Human Erythropoietin (rhEPO). Expanded and updated with new chapters, it describes scientific and clinical aspects of anemia, with diagnostic and therapeutic recommendations on use of rhEPO.

Автор: Marie-Luise Sautter-Bihl; Heiner Bihl; Michael Wan
Название: Systemic Radiotherapy with Monoclonal Antibodies
ISBN: 364279954X ISBN-13(EAN): 9783642799549
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Almost a century ago Paul Ehrlich introduced the "magic bullet" concept of targeting therapeutic agents to specific tissues in order to reduce systemic toxicity.

Автор: A. Szentivanyi; Paul H. Maurer; Bernard W. Janicki
Название: Antibodies
ISBN: 1461290449 ISBN-13(EAN): 9781461290445
Издательство: Springer
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Цена: 12157.00 р.
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Описание: This publication is based on a Symposium that has been held in Clearwater, Florida on February 19-21, 1986, on antibodies, their structure, synthesis, function, and clinical applicability in disease.

Автор: Roland E. Kontermann
Название: Bispecific Antibodies
ISBN: 3642432077 ISBN-13(EAN): 9783642432071
Издательство: Springer
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Цена: 30745.00 р.
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Описание: The concept of using bispecific antibodies for cancer therapy by retargeting immune effector cells was developed several years ago. Initial clinical studies were rather disappointing mainly due to low efficacy, severe side effects and the immunogenicity of the bispecific antibodies. The progress in antibody engineering finally led to the generation of new classes of bispecific antibodies lacking these obstacles. In addition, new applications were established, such as pre-targeting strategies in radioimmunotherapy and dual targeting approaches in order to improve binding, selectivity and efficacy. In this book, the different ways of generating bispecific antibodies are described, with emphasis on recombinant formats. The various applications of bispecific antibodies, e.g. in cellular cancer immunotherapy, radioimmunotherapy and pretargeting strategies are covered, and emerging applications such as dual targeting strategies, which involve the simultaneous inhibition of two targets, are addressed.

Автор: Dirk J. Ruiter; G.J. Fleuren; S.O. Warnaar
Название: Application of Monoclonal Antibodies in Tumor Pathology
ISBN: 9401079811 ISBN-13(EAN): 9789401079815
Издательство: Springer
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Цена: 15372.00 р.
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Описание: The development of monoclonal antibodies to human tumor associated antigens has greatly facilitated the application of immunohistochemical techniques to analyze surgically removed tissues. During the last few years this approach has been utilized by a progressively increasing number of investigators to analyze malignant cells. Although monoclonal antibodies to tumor associated antigens have not become yet routine reagents in immunopathology, they have provided new information which could not be obtained with conventional antisera or histochemical procedures. The following are representative examples. TUmor associated antigens have been identified which display a restricted distribution in normal tissues and therefore may represent useful markers for radio­ imaging and appropriate targets for immunotherapy. In spite of undetec­ table differences with conventional histopathological approaches hetero­ geneity has been found in the antigenic profile of tumor cells within a lesion, in autologous lesions removed from different anatomic sites from a given patient and in lesions removed from different patients. Phenotypes of tumor cells have been identified which correlate with the biology of tumor cells and with the clinical course of the disease. From a practical view point the use of monoclonal antibodies in immunopathology has enhanced interactions between pathologists and immunologists, as exemplified by the present book. Such interactions have contributed to the application of basic research to clinical problems. The chapter of this book discuss investigations performed with monoclonal antibodies to antigens expressed by various types of normal and malignant human cells.

Автор: John Landon; Tim Chard
Название: Therapeutic Antibodies
ISBN: 1447119398 ISBN-13(EAN): 9781447119395
Издательство: Springer
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Цена: 14365.00 р.
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Описание: Several aspects of clinical medicine are poised on the edge of a new era with the introduction of therapeutic antibodies. This volume is aimed at all clinicians involved with this form of treatment, especially accident and emergency physicians, clinical immunologists, and pharmacologists.

Автор: R. Ceriani
Название: Monoclonal Antibodies and Breast Cancer
ISBN: 0898387396 ISBN-13(EAN): 9780898387391
Издательство: Springer
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Цена: 33401.00 р.
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Описание: Proceedings of the International Workshop on Monoclonal Antibodies and Breast Cancer, held in San Francisco, California, November 8-9, 1984

Автор: Stewart Sell; Ralph Reisfeld
Название: Monoclonal Antibodies in Cancer
ISBN: 0896030687 ISBN-13(EAN): 9780896030688
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Monoclonal antibody technology from its earliest moments has offered revolutionary expectations for the diagnosis and treatment of cancer.

Автор: Benjamin Bonavida
Название: Resistance to Immunotherapeutic Antibodies in Cancer
ISBN: 1489987320 ISBN-13(EAN): 9781489987327
Издательство: Springer
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Цена: 19589.00 р.
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Описание: This book examines antibody-mediated anti-cancer therapy, covering the use of mAbs against various cancers, developments in the molecular, biochemical and genetic mechanisms of resistance by various mAbs and novel mAbs to overcome drug and radition resistance.