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New Approaches to the Treatment of Leukemia, Emil J. Freireich; A.M. Marmont; E.A. McCulloch; J
Emil J. Freireich; A.M. Marmont; E.A. McCulloch; J New Approaches to the Treatment of Leukemia 9783642754869

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Автор: Emil J. Freireich; A.M. Marmont; E.A. McCulloch; J
Название:  New Approaches to the Treatment of Leukemia
ISBN: 9783642754869
Издательство: Springer
Классификация:
Онкология

Гематология

ISBN-10: 3642754864
Обложка/Формат: Paperback
Страницы: 193
Вес: 0.48 кг.
Дата издания: 13.12.2011
Серия: ESO Monographs
Язык: English
Размер: 279 x 210 x 11
Основная тема: Medicine & Public Health
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The European School of Oncology came into existence to respond to a need for informa- tion, education and training in the field of the diagnosis and treatment of cancer. There are two main reasons why such an initiative was considered necessary. Firstly, the teaching of oncology requires a rigorously multidisciplinary approach which is difficult for the Universi- ties to put into practice since their system is mainly disciplinary orientated. Secondly, the rate of technological development that impinges on the diagnosis and treatment of cancer has been so rapid that it is not an easy task for medical faculties to adapt their curricula flexibly. With its residential courses for organ pathologies and the seminars on new techniques (laser, monoclonal antibodies, imaging techniques etc.) or on the principal therapeutic controversies (conservative or mutilating surgery, primary or adjuvant chemotherapy, radiotherapy alone or integrated), it is the ambition of the European School of Oncology to fill a cultural and scientific gap and, thereby, create a bridge between the University and Industry and between these two and daily medical practice.


Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia

Автор: Masahiro Kizaki
Название: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia
ISBN: 4431562559 ISBN-13(EAN): 9784431562559
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development.

New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia

Автор: W. Hiddemann; R. Mertelsmann
Название: New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia
ISBN: 3540526137 ISBN-13(EAN): 9783540526131
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Provides information about the current status of aclacinomycin A for the treatment of haematologic malignancies. The text includes accounts of the action of aclacinomycin A in myelodysplastic syndromes and of its efficacy in acute myeloid leukemias.

Leukemia: Advances in Research and Treatment

Автор: Emil J. Freireich; Hagop Kantarjian
Название: Leukemia: Advances in Research and Treatment
ISBN: 1461363489 ISBN-13(EAN): 9781461363484
Издательство: Springer
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Цена: 13974.00 р.
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Описание: As a result, this multi-authored volume, devoted to advances which have occurred over the last seven years, provides the reader with an important new understanding of leukemia, but perhaps even more important, predicts analogous, new developments in the other malignant diagnoses.

Childhood leukemia

Автор: Reaman
Название: Childhood leukemia
ISBN: 3642137806 ISBN-13(EAN): 9783642137808
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book is a comprehensive and up-to-date compendium on all aspects of childhood leukemia. After introductory chapters on the epidemiology and biology of pediatric leukemia, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. Promising targeted agents are discussed, and strategies for the development of new agents are appraised. The late effects of leukemia and its therapy are then considered in depth, with due attention to management of the psychosocial impact of the disease. Finally, global strategies to improve leukemia care and outcome are reviewed, and future directions discussed. The authors are internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric leukemia and will prove invaluable to specialists, generalists, and trainees alike.

Childhood Leukemia: Present Problems and Future Prospects

Автор: Noburo Kobayashi; Tai Akera; Shuki Mizutani
Название: Childhood Leukemia: Present Problems and Future Prospects
ISBN: 0792311388 ISBN-13(EAN): 9780792311386
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Proceedings of the Second International Symposium on Children`s Cancer and Childhood Leukemia -- Present Problems and Future Prospects, December 7-9, 1989

New Agents for the Treatment of Acute Lymphoblastic Leukemia

Автор: Vaskar Saha; Pamela Kearns
Название: New Agents for the Treatment of Acute Lymphoblastic Leukemia
ISBN: 1489985719 ISBN-13(EAN): 9781489985712
Издательство: Springer
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Цена: 26120.00 р.
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Описание: It is increasingly recognized that the natural history of cancer formation is a complex path taking many years to develop to a clinically apparent stage in most cases. However, with advancing knowledge comes a whole plethora of questions explored in this book.

Chronic Myeloid Leukemia

Автор: Shaoguang Li; Haojian Zhang
Название: Chronic Myeloid Leukemia
ISBN: 1493940090 ISBN-13(EAN): 9781493940097
Издательство: Springer
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Цена: 18167.00 р.
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Описание:

1. Molecular Detection of BCR-ABL in Chronic Myeloid Leukemia

Ya-Zhen Qin and Xiao-Jun Huang

2. Induction of Chronic Myeloid Leukemia in Mice

Haojian Zhang and Shaoguang Li

3. CML Mouse Model Generated from Leukemia Stem Cells

Yiguo Hu

4. Immunological Analyses of Leukemia Stem Cells

Kazuhito Naka and Yoshihiro Takihara

5. Cell Cycle Analysis of CML Stem Cells using Hoechst33342 and Propidium Iodide

Ngoc DeSouza, Megan Zhou, and Yi Shan

6. Histological and In Vivo Microscopic Analysis of the Bone Marrow Microenvironment in a Murine Model of Chronic Myelogenous Leukemia

Eva S. Weissenberger and Daniela S. Krause

7. The Culture Repopulation Ability (CRA) Assay and Incubation in Low Oxygen to Test Anti-Leukemic Drugs on Imatinib-resistant CML Stem-like Cells

Giulia Cheloni and Michele Tanturli

8. Tumor Suppressor Analysis in CML

Oliver Herrmann and Mirle Schemionek

9. Detecting Autophagy and Autophagy Flux in Chronic Myeloid Leukemia Cells Using a Cyto ID Fluorescence Spectrophotometric Assay

Sujuan Guo, Kevin Pridham, and Zhi Sheng

10. DREAM, A Simple Method for DNA Methylation Profiling by High Throughput Sequencing

Jaroslav Jelinek and Jozef Madzo

11. ChIP-seq Analysis of Human Chronic Myeloid Leukemia Cells

Lars Anders and Zhaodong Li

12. Quantitative Proteomics Analysis of Leukemia Cells

Sebastian Halbach, Jцrn Dengjel, and Tilman Brummer

13. A Convenient Cell Culture Model for CML Acquired Resistance through BCR-ABL Mutations

Zhiqiang Wang and WenYong Chen

14. High Throughput Screening of Tyrosine Kinase Inhibitor Resistant Genes in CML

Leyuan Ma, Justine Roderick, Michelle A. Kelliher, and Michael R. Green

15. Biological Analysis of Human CML Stem Cells; Xenograft Model of Chronic Phase Human Chronic Myeloid Leukemia

Sheela A. Abraham

16. New Mouse Models to Investigate the Efficacy of Drug Combinations in Human Chronic Myeloid Leukemia

Hanyang Lin, Adrian Woolfson, and Xiaoyan Jiang

17. miRNome Analysis of CML Cells

Yadong Yang, Nan Ding, Xunong Dong, Xiangdong Fang

18. An Integrative Analysis of microRNA and mRNA Profiling in CML Stem Cells

Farah Nassar, Rabab El Eit, and Rihab Nasr

19. Single Cell Cytokine Profiling to Investigate Cellular Functional Diversity in Hematopoietic Malignancies

Jonathan J. Chen, Minsuk Kwak, and Rong Fan
Leukemia: Advances in Research and Treatment

Автор: Emil J. Freireich; Hagop Kantarjian
Название: Leukemia: Advances in Research and Treatment
ISBN: 0792319672 ISBN-13(EAN): 9780792319672
Издательство: Springer
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Цена: 51570.00 р.
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Molecular Genetics and Therapy of Leukemia

Автор: Emil J. Freireich; Hagop Kantarjian
Название: Molecular Genetics and Therapy of Leukemia
ISBN: 0792339126 ISBN-13(EAN): 9780792339120
Издательство: Springer
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Цена: 58557.00 р.
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Описание: Leukemia is a malignant disease which continues to play a cutting edge role in the discovery of basic knowledge about the malignant process and about the potential for controlling these malignant diseases. This title covers such topics as chromosome 16, chromosome 5, the BCL-2 gene, 11q23 breakpoint leukemias, and hematopoietic stem cells.

Drug Resistance in Leukemia and Lymphoma III

Автор: G.J.L. Kaspers; R. Pieters; A.J.P. Veerman
Название: Drug Resistance in Leukemia and Lymphoma III
ISBN: 0306460556 ISBN-13(EAN): 9780306460555
Издательство: Springer
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Цена: 38992.00 р.
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Описание: This volume covers all important aspects of drug resistance in leukemia and lymphoma. General mechanisms of resistance are discussed, including the drug resistance related proteins, MRP (multi drug resistance protein) and LRP (lung resistance protein), and the role of glutathione.

Targeted Therapy of Acute Myeloid Leukemia

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493939890 ISBN-13(EAN): 9781493939893
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.


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