Molecular Genetics and Therapy of Leukemia, Emil J. Freireich; Hagop Kantarjian

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493939890 ISBN-13(EAN): 9781493939893
Издательство: Springer
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Цена: 25155.00 р.
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Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Автор: Kaspers Et Al
Название: Innovative Leukemia and Lymphoma Therapy
ISBN: 0849350832 ISBN-13(EAN): 9780849350832
Издательство: Taylor&Francis
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Цена: 22202.00 р.
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Описание: Innovative Leukemia and Lymphoma Therapy provides a complete and up-to-date overview of the exciting new treatment modalities in leukemia and lymphoma that are being introduced in the clinic today.

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493913921 ISBN-13(EAN): 9781493913923
Издательство: Springer
Рейтинг:
Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Автор: Emil J. Freireich; Hagop Kantarjian
Название: Molecular Genetics and Therapy of Leukemia
ISBN: 1461285372 ISBN-13(EAN): 9781461285373
Издательство: Springer
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Цена: 58557.00 р.
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Описание: Leukemia is a malignant disease which continues to play a cutting edge role in the discovery of new basic knowledge about the malignant process and about the potential for controlling these malignant diseases.
Molecular Genetics and Therapy of Leukemia presents contributions by leading investigators and scientific contributors to such topics as chromosome 16, chromosome 5, the BCL-2 gene, 11q23 breakpoint leukemias, the p-53 suppressor gene and oncogene, hematopoietic stem cells, cytokines, detection of minimal residual disease in acute lymphoblastic leukemia, autologous marrow transplantation, the retinoblastoma gene, allogeneic bone marrow transplant and chemotherapy of acute lymphoblastic leukemia.

Автор: Masahiro Kizaki
Название: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia
ISBN: 4431562559 ISBN-13(EAN): 9784431562559
Издательство: Springer
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Цена: 16769.00 р.
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Описание: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development.

Автор: L.O. Baker; Frederick A. Valeriote; Voravit Ratana
Название: Biology and Therapy of Acute Leukemia
ISBN: 0898387280 ISBN-13(EAN): 9780898387285
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Proceedings of the Seventeenth Annual Detroit Cancer Symposium, held in Detroit, Michigan, April 12-13, 1984

Автор: L.O. Baker; Frederick A. Valeriote; Voravit Ratana
Название: Biology and Therapy of Acute Leukemia
ISBN: 1461296331 ISBN-13(EAN): 9781461296331
Издательство: Springer
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Цена: 27951.00 р.
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Описание: Proceedings of the Seventeenth Annual Detroit Cancer Symposium, held in Detroit, Michigan, April 12-13, 1984

Автор: Noburo Kobayashi; Tai Akera; Shuki Mizutani
Название: Childhood Leukemia: Present Problems and Future Prospects
ISBN: 1461367395 ISBN-13(EAN): 9781461367390
Издательство: Springer
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Цена: 20962.00 р.
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Описание: Proceedings of the Second International Symposium on Children`s Cancer and Childhood Leukemia -- Present Problems and Future Prospects, December 7-9, 1989

Автор: Rolf Neth; Robert C. Gallo; Melvyn F. Greaves; Gri
Название: Modern Trends in Human Leukemia VI
ISBN: 3540153292 ISBN-13(EAN): 9783540153290
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Organized on behalf of the Deutsche Gesellschaft fur Hamatologie und Onkologie. Wilsede, June 17-20, 1984 Wilsede Joint Meeting on Pediatric Oncology III. Hamburg, June 21/22, 1984.

Автор: Wolf-Dieter Ludwig; Eckhard Thiel
Название: Recent Advances in Cell Biology of Acute Leukemia
ISBN: 3642848974 ISBN-13(EAN): 9783642848971
Издательство: Springer
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Цена: 18167.00 р.
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Описание: The development of new techniques such as immuno- phenotyping, cytogenetic investigations and, more recently, molecular studies has considerably increased our diagnostic repertoire and broadened our ideas about the biology of acute leukemias.

Автор: Shaoguang Li; Haojian Zhang
Название: Chronic Myeloid Leukemia
ISBN: 1493940090 ISBN-13(EAN): 9781493940097
Издательство: Springer
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Цена: 18167.00 р.
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Описание:

1. Molecular Detection of BCR-ABL in Chronic Myeloid Leukemia