Molecular Genetics and Therapy of Leukemia, Emil J. Freireich; Hagop Kantarjian
Автор: Michael Andreeff Название: Targeted Therapy of Acute Myeloid Leukemia ISBN: 1493939890 ISBN-13(EAN): 9781493939893 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.
Автор: Michael Andreeff Название: Targeted Therapy of Acute Myeloid Leukemia ISBN: 1493913921 ISBN-13(EAN): 9781493913923 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.
Автор: L.O. Baker; Frederick A. Valeriote; Voravit Ratana Название: Biology and Therapy of Acute Leukemia ISBN: 1461296331 ISBN-13(EAN): 9781461296331 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Seventeenth Annual Detroit Cancer Symposium, held in Detroit, Michigan, April 12-13, 1984
Автор: Kaspers Et Al Название: Innovative Leukemia and Lymphoma Therapy ISBN: 0849350832 ISBN-13(EAN): 9780849350832 Издательство: Taylor&Francis Рейтинг: Цена: 22202.00 р. Наличие на складе: Поставка под заказ.
Описание: Innovative Leukemia and Lymphoma Therapy provides a complete and up-to-date overview of the exciting new treatment modalities in leukemia and lymphoma that are being introduced in the clinic today.
Автор: Emil J. Freireich; Hagop Kantarjian Название: Molecular Genetics and Therapy of Leukemia ISBN: 0792339126 ISBN-13(EAN): 9780792339120 Издательство: Springer Рейтинг: Цена: 58557.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leukemia is a malignant disease which continues to play a cutting edge role in the discovery of basic knowledge about the malignant process and about the potential for controlling these malignant diseases. This title covers such topics as chromosome 16, chromosome 5, the BCL-2 gene, 11q23 breakpoint leukemias, and hematopoietic stem cells.
Описание: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development.
Автор: L.O. Baker; Frederick A. Valeriote; Voravit Ratana Название: Biology and Therapy of Acute Leukemia ISBN: 0898387280 ISBN-13(EAN): 9780898387285 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Seventeenth Annual Detroit Cancer Symposium, held in Detroit, Michigan, April 12-13, 1984
Автор: Paolo Fortina; Eric Londin; Jason Y. Park; Larry J Название: Acute Myeloid Leukemia ISBN: 1493971409 ISBN-13(EAN): 9781493971404 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival.
Автор: Renato Mastrangelo; D.G. Poplack; Riccardo Riccard Название: Central Nervous System Leukemia ISBN: 9400967101 ISBN-13(EAN): 9789400967106 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Although successful in most cases, eNS preventive therapy remains ineffective for a small but significant subset of patients at high risk for developing eNS disease. Moreover, it has become increasingly evident that some methods of eNS preventive therapy are associated with long-term, adverse eNS sequelae.
Автор: Emil J. Freireich; A.M. Marmont; E.A. McCulloch; J Название: New Approaches to the Treatment of Leukemia ISBN: 3642754864 ISBN-13(EAN): 9783642754869 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The European School of Oncology came into existence to respond to a need for informa- tion, education and training in the field of the diagnosis and treatment of cancer. There are two main reasons why such an initiative was considered necessary. Firstly, the teaching of oncology requires a rigorously multidisciplinary approach which is difficult for the Universi- ties to put into practice since their system is mainly disciplinary orientated. Secondly, the rate of technological development that impinges on the diagnosis and treatment of cancer has been so rapid that it is not an easy task for medical faculties to adapt their curricula flexibly. With its residential courses for organ pathologies and the seminars on new techniques (laser, monoclonal antibodies, imaging techniques etc.) or on the principal therapeutic controversies (conservative or mutilating surgery, primary or adjuvant chemotherapy, radiotherapy alone or integrated), it is the ambition of the European School of Oncology to fill a cultural and scientific gap and, thereby, create a bridge between the University and Industry and between these two and daily medical practice.
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