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Anticancer Drug Development Guide, Beverly A. Teicher; Paul A. Andrews


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Автор: Beverly A. Teicher; Paul A. Andrews
Название:  Anticancer Drug Development Guide
ISBN: 9781468498417
Издательство: Springer
Классификация:

ISBN-10: 146849841X
Обложка/Формат: Paperback
Страницы: 451
Вес: 0.80 кг.
Дата издания: 08.08.2012
Серия: Cancer Drug Discovery and Development
Язык: English
Издание: Softcover reprint of
Иллюстрации: 161 illustrations, black and white; xiv, 451 p. 161 illus.
Размер: 254 x 178 x 24
Читательская аудитория: Professional & vocational
Основная тема: Medicine & Public Health
Подзаголовок: Preclinical Screening, Clinical Trials, and Approval
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of antileukemia agents, but that other tumor models would be needed to discover drugs active against solid tumors.


Chemistry and Pharmacology of Anticancer Drugs, Second Edition

Автор: Thurston
Название: Chemistry and Pharmacology of Anticancer Drugs, Second Edition
ISBN: 1439853266 ISBN-13(EAN): 9781439853269
Издательство: Taylor&Francis
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Цена: 19906.00 р.
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Описание: This book is a comprehensive survey of all families of anticancer agents and therapeutic approaches. The book will acts as an indispensable resource for researchers, medicinal chemists and biomedical scientists. The new edition of this book will also have a Companion Website.

Anticancer Therapeutics

Автор: Missailidis
Название: Anticancer Therapeutics
ISBN: 0470723033 ISBN-13(EAN): 9780470723036
Издательство: Wiley
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Цена: 24386.00 р.
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Описание: Written by the winner of the 2008 Mike Price Fellowship The need to re-address known anti-cancer agents and discover new ones are of paramount importance. Anticancer Therapeutics provides a comprehensive overview of the wealth of information currently available on this important and fast-moving subject.

Medicinal Chemistry of Anticancer Drugs

Автор: Carmen Avendano
Название: Medicinal Chemistry of Anticancer Drugs
ISBN: 0444626492 ISBN-13(EAN): 9780444626493
Издательство: Elsevier Science
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Цена: 23244.00 р.
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Описание: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. . Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. . Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design.

Anticancer Drug Development Guide

Автор: Beverly A. Teicher
Название: Anticancer Drug Development Guide
ISBN: 1461581540 ISBN-13(EAN): 9781461581543
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Experienced cancer researchers from pharmaceutical companies, government laboratories, and academia comprehensively review and describe the arduous process of cancer drug discovery and approval.

Human Tumour Xenografts in Anticancer Drug Development

Автор: Benjamin Winograd; Michael Peckham; Herbert M. Pin
Название: Human Tumour Xenografts in Anticancer Drug Development
ISBN: 3642732542 ISBN-13(EAN): 9783642732546
Издательство: Springer
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Цена: 19591.00 р.
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Описание: Seminar on Human Tumour Xenografts 1986, Milan, Italy. European School of Oncology

Anticancer Drug Development Guide. 2ed.2004

Автор: Teicher
Название: Anticancer Drug Development Guide. 2ed.2004
ISBN: 1588292282 ISBN-13(EAN): 9781588292285
Издательство: Springer
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Цена: 34799.00 р.
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Описание: This thoroughly updated and expanded second edition of Beverly Teicher's widely used classic survey provides a step-by-step guide to anticancer drug development from initial design through FDA approval. The authors have included new material on the use of high throughput screening in industry, on specialized in vitro/in vivo procedures employed by the National Cancer Institute (NCI) in preclinical drug evaluations, and on nonclinical testing to support both human clinical trials, as well as trials of biologic oncology products. The chapters on phase I, II, and III clinical trials and on novel phase II clinical trial designs for targeted therapies have been significantly updated, along with those on cancer drug development in Europe, working with the NCI, and the FDA's role in cancer drug development and setting requirements for approval.

Principles of Anticancer Drug Development

Автор: Elizabeth Garrett-Mayer; Manuel Hidalgo; S. Gail E
Название: Principles of Anticancer Drug Development
ISBN: 1461427916 ISBN-13(EAN): 9781461427919
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This is a practical guide to the design, conduction, analysis and reporting of clinical trials with anticancer drugs. It includes coverage of basic biostatistics for the clinical trialist, and fundamental concepts in clinical pharmacology.

Mechanism of the Anticancer Effect of Phytochemicals

Автор: Bathaie S.
Название: Mechanism of the Anticancer Effect of Phytochemicals
ISBN: 0128038764 ISBN-13(EAN): 9780128038765
Издательство: Elsevier Science
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Цена: 18528.00 р.
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Описание: Volume 37 will provide details on the major chemical constituents of medicinal plants and their mechanism of action as the anticancer compounds. This special issue, in addition to the previous volume (volume 36 of The Enzyme series was on Natural Products and Cancer Signaling Targets: Isoprenoids, Polyphenols and Flavonoids), will highlight the significant advance made in the field in elucidating mechanisms of anticancer effect of the major phytochemicals.

Molecular and Clinical Advances in Anticancer Drug Resistance

Автор: Robert F. Ozols
Название: Molecular and Clinical Advances in Anticancer Drug Resistance
ISBN: 0792312120 ISBN-13(EAN): 9780792312123
Издательство: Springer
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Цена: 37594.00 р.
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Описание: The importance of drug resistance in cancer chemotherapy cannot be over- stated. The 500,000 patients who die every year from cancer in the United States have, in most cases, been treated with chemotherapy. Many of these patients responded initially to chemotherapy, but death resulted from the development of drug-resistant tumors. In the first volume in the series. Drug Resistance in Chemotherapy the results of comprehensive laboratory studies aimed at understanding the mechanisms for resistance to individual agents and to the development of broad cross-resistance were described. In the past 2 years there has been substantial progress in understanding the molecular biology associated with these mechanisms of drug resistance. For the first time we are starting to understand which mechanisms are playing an im- portant role in human tumors, and even more importantly, clinical trials have recently been initiated in an effort to reverse specific forms of drug resistance. The purpose of this volume is to describe the new advances, both at the molecular level and in the clinic regarding mechanisms of drug resistance and potential ways this resistance can be circumvented. This volume is focused upon mechanisms of resistance associated with two major classes of anticancer drugs: alkylating agents (including cisplatin) and the natural products (e. g., adriamycin and vinblastine). The first section of the book describes new insights into the genetic mechanisms associated with drug resistance.

Handbook of Anticancer Drugs from Marine Origin

Автор: Se-Kwon Kim
Название: Handbook of Anticancer Drugs from Marine Origin
ISBN: 3319071440 ISBN-13(EAN): 9783319071442
Издательство: Springer
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Цена: 34937.00 р.
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Описание: This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.


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