The Chemokines, I.J.D. Lindley; J. Westwick; S. Kunkel
Автор: Astrid E. Cardona; Eroboghene E. Ubogu Название: Chemokines ISBN: 1627034250 ISBN-13(EAN): 9781627034258 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology book offers experimental models and state-of-the-art methods used to delineate chemokine/chemokine receptor function and applications in health and disease. Includes materials lists, reproducible protocols, pitfalls and more.
Автор: Nuska Tschammer Название: Chemokines ISBN: 3319347837 ISBN-13(EAN): 9783319347837 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction.- Insights in the chemokine receptor structures and drug design approaches in chemokine receptors.- Therapeutic targeting of CXCR3 chemokine receptor by small molecules.- Allosteric modulation of chemokine receptors.- Chemokines and their receptors in CNS.- Chemokine receptors in allergy and inflammation
Автор: Nuska Tschammer Название: Chemokines ISBN: 3319140590 ISBN-13(EAN): 9783319140599 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction.- Insights in the chemokine receptor structures and drug design approaches in chemokine receptors.- Therapeutic targeting of CXCR3 chemokine receptor by small molecules.- Allosteric modulation of chemokine receptors.- Chemokines and their receptors in CNS.- Chemokine receptors in allergy and inflammation
Автор: Caroline A. H?bert Название: Chemokines in Disease ISBN: 1475747624 ISBN-13(EAN): 9781475747621 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Caroline Hebert and a panel of key experimentalists and clinical investigators comprehensively review the state-of-the-art in the chemokine field, ranging from the effects of chemokines and their receptors in retroviral infections, to their role in inflammation, angiogenesis/angiostasis, and tumor cell biology.
Автор: Philip M. Murphy; Richard Horuk Название: Chemokine Roles in Immunoregulation and Disease ISBN: 3662054051 ISBN-13(EAN): 9783662054055 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Amanda E.I. Proudfoot; Timothy N.C. Wells; Christi Название: Chemokine Protocols ISBN: 0896037223 ISBN-13(EAN): 9780896037229 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: What has emerged over the years is that most chemokine receptors bind several distinct ligands, and indeed the majority of chemokines are able to bind to multiple chemokine receptors, explaining to some extent the apparent disparity in the numbers of chemokines and rec- tors.
Автор: Pere Santamaria; Peter Hackett Название: Cytokines and Chemokines in Autoimmune Disease ISBN: 1461349524 ISBN-13(EAN): 9781461349525 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is ideal for individuals interested in taking an in-depth look at how cytokines and chemokines participate in autoimmune disorders, and how cytokines and chemokines can be used as targets for therapeutic intervention.
Автор: Astrid E. Cardona; Eroboghene E. Ubogu Название: Chemokines ISBN: 1493960059 ISBN-13(EAN): 9781493960057 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology book offers experimental models and state-of-the-art methods used to delineate chemokine/chemokine receptor function and applications in health and disease. Includes materials lists, reproducible protocols, pitfalls and more.
Автор: Kownatzki; Norgauer Название: Chemokines and Skin ISBN: 3034897979 ISBN-13(EAN): 9783034897976 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The accumulation of white blood cells is a hallmark of inflammation. The penetra- tion through the vessel walls and the infiltration around the inflammatory stimulus is a complex process which involves active adherence and directed migration of the inflammatory cells. Chemotactic factors stimulate both adherence and migration. Technical tools such as the Boyden chamber 1] made it possible to study leukocyte migration in vitro. This technique allows differentiation between migration direct- ed towards a chemotactic stimulus and non-directed migration. Until a decade ago only two naturally occurring molecules had been clearly iden- tified as potent chemotactic attractants of neutrophilic granulocytes. They were the split product of the fifth complement component C5a 2] and the arachidonic acid metabolite leukotriene B4 3]. In 1986, a novel human monocyte-derived chemo- taxin attracting neutrophilic granulocytes with a similar potency was found 4]. This report was quickly confirmed by several groups 5-8]. The new factor was purified, cloned and sequenced 9, 10]. The term "interleukin 8" (IL-8) replaced the various names proposed previously 4-8]. Sequence data revealed that IL-8 belonged to a large family of chemotactic cytokines, now called "chemokines" 11]. Four subfamilies were distinguished on the basis of the number and position of the first cysteine residues. They are desig- nated accordingly as C, CC, CXC and CX C chemokines 11-13]. The number of 3 human chemokines identified so far is close to 40 11-13].
Автор: Tracy Handel Название: Chemokines,570 ISBN: 0128021713 ISBN-13(EAN): 9780128021712 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"Chemokines," the latest volume in the "Methods in Enzymology" series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in chemokines, and includes sections on such topics as chemokine detection using receptors, tracking cellular responses to chemokines, recognition of GAG-bound chemokines, and the production of chemokine receptor complexes for structural and biophysical studies. Continues the legacy of this premier serial with quality chapters authored by leaders in the fieldCovers research methods in chemokinesContains sections on such topics as chemokine detection using receptors, tracking cellular responses to chemokine, recognition of GAG-bound chemokines, and the production of chemokine receptor complexes for structural and biophysical studies
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