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Novel Approaches to Selective Treatments of Human Solid Tumors, Youcef M. Rustum


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Автор: Youcef M. Rustum
Название:  Novel Approaches to Selective Treatments of Human Solid Tumors
ISBN: 9781461360605
Издательство: Springer
Классификация:




ISBN-10: 1461360609
Обложка/Формат: Paperback
Страницы: 319
Вес: 0.58 кг.
Дата издания: 24.10.2012
Серия: Advances in Experimental Medicine and Biology
Язык: English
Размер: 254 x 178 x 18
Основная тема: Medicine & Public Health
Подзаголовок: Laboratory and Clinical Correlation
Ссылка на Издательство: Link
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Поставляется из: Германии


Selective Antibiotic Use in Respiratory Illness: a Family Practice Guide

Автор: M.T. Everett
Название: Selective Antibiotic Use in Respiratory Illness: a Family Practice Guide
ISBN: 9401511454 ISBN-13(EAN): 9789401511452
Издательство: Springer
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Цена: 12157.00 р.
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Описание: by comparing him to a soldier in the trenches of World War I. In the trenches the soldier seldom forgets that the next moment may bring death or crippling. The haemophiliac is literally in the trenches. For the soldiers that survived World War I in the trenches. War can come to an oasis, peace can come to the trenches.

Selective Breeding in Aquaculture: an Introduction

Автор: Trygve Gjedrem; Matthew Baranski
Название: Selective Breeding in Aquaculture: an Introduction
ISBN: 9400736770 ISBN-13(EAN): 9789400736771
Издательство: Springer
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Цена: 25155.00 р.
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Описание: Unfortunately, the subsequent implementation of selective breeding on a wider scale in aquaculture has been slow, and despite the dramatic gains that have been demonstrated in a number of species, less than 10% of world aquaculture production is currently based on improved stocks.

Functional and Selective Neck Dissection

Автор: Javier Gavilan
Название: Functional and Selective Neck Dissection
ISBN: 3131246316 ISBN-13(EAN): 9783131246318
Издательство: Thieme Verlagsgruppe
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Цена: 24773.00 р.
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Описание: With a whole new approach to neck dissection, this superb book examines the differences between surgical techniques and conceptual approaches to neck dissection. It strives to connect the two points of view, beginning with a historical perspective of the procedure from both the American and Latin perspective. The book creates a better understanding of the reasons behind selective neck dissection, starting with an explanation of the fascial compartmentalization of the neck. This is a step-by-step guide to the operative technique of functional and other non-radical neck dissections. A full list of technical hints and pitfalls, along with nearly 200 color photographs and drawings, are included to enhance the learning process. The book is essential for any professional that wants to understand the rationale, indications, and results of the functional approach to the neck, including otolaryngologists, head and neck surgeons, maxillofacial surgeons, plastic surgeons, and general surgeons.

Selective Sentinel Lymphadenectomy for Human Solid Cancer

Автор: Stanley P. L. Leong; Yuko Kitagawa; Masaki Kitajim
Название: Selective Sentinel Lymphadenectomy for Human Solid Cancer
ISBN: 1489988696 ISBN-13(EAN): 9781489988690
Издательство: Springer
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Цена: 18167.00 р.
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Описание:

In human solid cancer, the lymph node (LN) status is the most important prognostic indicator for the clinical outcome of patients. Recent developments in the sentinel lymph node (SLN) concept and technology have resulted in the application of this revolutionary approach to define the first draining or SLN to which the cancer may have metastasized. The underlying thesis in solid cancer biology is that metastasis generally starts in an orderly progression, spreading through the lymphatic channels to the SLN in the nearest LN basin. Thus, the logical approach is to harvest that specific SLN for thorough analysis. Because a tumorfree SLN is usually associated with a negative residual LN basin, a negative SLN is an excellent indication that micrometastasis has not occurred in the regional LNs. When the SLN is involved, it is unknown whether or not metastasis is limited only to the SLN or if the disease has spread to the remainder of the nodal basin. For this reason, if a SLN is positive, a complete lymph node dissection is recommended. Therefore, selective sentinel lymphadenectomy (SSL) should be considered as a staging procedure so that patients with negative SLNs (about 80%) may be spared an extensive LN dissection. Malignant melanoma has been proven to be the most ideal tumor model to study the role of SLN. Subsequently, SSL has been applied to breast cancer, colon cancer and other types of solid cancer. The multidisciplinary approach encompassing the surgeon, nuclear medicine physician, and pathologist is the key to such a successful procedure. Such a team can be formed readily with appropriate training. Beyond the technical aspects of harvesting the SLN, the implication of micrometastasis remains to be defined. Because the follow-up of melanoma and breast cancer patients after SSL is crucial, ongoing clinical trials are in progress to determine the biological and clinical significance of SLNs. Although the concept of SLN is viable in other types of cancer, such as gynecological and gastrointestinal, the technical aspects of the procedure need to be perfected and verified. The most exciting possibility of SSL is that it will lead to early diagnosis of micrometastasis in regional LNs. Early diagnosis makes it useful as a clinical staging procedure, and opens up new opportunities to study micrometastasis and its evolution within the SLNs. Examining the multifaceted aspects of micrometastasis, such as differentiation of different clones with respect to the primary tumor, acquisition of adhesion molecules, and host interaction with the microscopic tumor, will shed new light on the biology of early metastasis. New molecular and genetic tools may be used to dissect the mechanisms of lymphatic and hemo togenous routes of metastasis. If such mechanisms can be understood, new therapeutic advances may be developed to prevent the process of micrometastasis. Rather than targeting larger tumor burdens such as Stage IV disease, targeted adjuvant clinical trials can be developed for high risk patients following definit ive surgical resection. SSL is a standard staging procedure for patients with melanoma and is rapidly evolving into a standard procedure for breast cancer as well.

Cancer Chemotherapy and Selective Drug Development

Автор: K.R. Harrap; W. Davis; A.H. Calvert
Название: Cancer Chemotherapy and Selective Drug Development
ISBN: 1461338395 ISBN-13(EAN): 9781461338390
Издательство: Springer
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Цена: 30606.00 р.
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Описание: Proceedings of the 10th Anniversary Meeting of the Coordinating Committee for Human Tumour Investigations, Brighton, England (24-28 October 1983)

Cancer Chemotherapy and Selective Drug Development

Автор: K.R. Harrap; W. Davis; A.H. Calvert
Название: Cancer Chemotherapy and Selective Drug Development
ISBN: 089838673X ISBN-13(EAN): 9780898386738
Издательство: Springer
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Цена: 44582.00 р.
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Описание: Proceedings of the 10th Anniversary Meeting of the Coordinating Committee for Human Tumour Investigations, Brighton, England (24-28 October 1983)

Selective Activation of Drugs by Redox Processes

Автор: G.E. Adams; A. Breccia; E.M. Fielden; P. Wardman
Название: Selective Activation of Drugs by Redox Processes
ISBN: 1461366798 ISBN-13(EAN): 9781461366799
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Proceedings of a NATO ARW held in Fermo, Italy, August 28-September 1, 1989

Selective Toxicity

Автор: Adrien Albert
Название: Selective Toxicity
ISBN: 0412260204 ISBN-13(EAN): 9780412260209
Издательство: Springer
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Цена: 12157.00 р.
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Описание: This book is about selectively toxic agents. Selective toxicity covers an immense field: most of the drugs used for treating illness in man and his economic animals, as well as all of the fungicides, insecticides, and weed killers that are used in agriculture.

Highly Selective Separations in Biotechnology

Автор: G. Street
Название: Highly Selective Separations in Biotechnology
ISBN: 0751400513 ISBN-13(EAN): 9780751400519
Издательство: Springer
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Цена: 34380.00 р.
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Описание: Provides a comprehensive account of the principles and applications of highly selective separations in biotechnology, including the use of membranes and phase boundaries.

Chromosome 12 Aberrations in Human Solid Tumors

Автор: J?rn Bullerdiek; H. Van den Berghe; Sabine Bartnit
Название: Chromosome 12 Aberrations in Human Solid Tumors
ISBN: 3662062577 ISBN-13(EAN): 9783662062579
Издательство: Springer
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Цена: 16979.00 р.
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Sellar and Parasellar Tumors: Diagnosis, Treatments, and Outcomes

Автор: Edward R. Laws
Название: Sellar and Parasellar Tumors: Diagnosis, Treatments, and Outcomes
ISBN: 1604064218 ISBN-13(EAN): 9781604064216
Издательство: Thieme Verlagsgruppe
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Цена: 23121.00 р.
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Описание: Focusing on the variety of pathological processes that arise in the sellar and parasellar regions of the central skull base, Sellar and Parasellar Tumors: Diagnosis, Treatments, and Outcomes is a state-of-the-art reference written by renowned leaders in the field. It takes a disease-oriented approach to complex pathologies. The work includes contributions by multispecialty teams and details technical advances and management options for all clinicians treating patients with parasellar and sellar pathology. Special Features •Represents the multidisciplinary management of these cases, with contributions from neurological surgeons, otolaryngologists, radiation oncologists, diagnostic radiologists, endocrinologists, and ophthalmologists •Covers the many diverse tumor types found in the sellar and parasellar region--including pituitary tumors, meningiomas, chordomas, and chondrosarcomas --with clinical management strategies for each •Provides detailed, illustrated descriptions of optimal surgical approaches tailored to the patient and pathology—including transsphenoidal surgery, precise craniotomies using skull base techniques, minimally invasive eyebrow exposures, endoscopic anterior skull base techniques, and stereotactic radiosurgery •Discusses the advantages and disadvantages of different surgical approaches, tips for complication avoidance, patient evaluation methods, surgical indications and outcomes, and more •Includes comprehensive neuroanatomic dissections that provide visualization of the entire sellar and parasellar region •Offers radiologic, medical, and ophthalmologic management techniques for patients with sellar and parasellar tumors Complete with full-color illustrations, high-quality radiographs, and instructive tables, Sellar and Parasellar Tumors is the authoritative reference for neurosurgeons, otolaryngologists, endocrinologists, neuro-ophthalmologists, radiation oncologists, and any other clinician who diagnoses, treats, and manages patients with these complex disorders.

Selective Heat Sensitivity of Cancer Cells

Автор: A. Rossi-Fanelli; R. Cavaliere; B. Mondovi; G. Mor
Название: Selective Heat Sensitivity of Cancer Cells
ISBN: 3642810829 ISBN-13(EAN): 9783642810824
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Sponsored by the Swiss League against Cancer


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