High Throughput Screening for Novel Anti-Inflammatories, Michael Kahn

Автор: Zhu
Название: High-Throughput Screening Assays in Toxicology
ISBN: 1493963449 ISBN-13(EAN): 9781493963447
Издательство: Springer
Рейтинг:
Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book focuses on recently developed High Throughput Screening (HTS) assay protocols, many involved in the ToxCast and/or Tox21 initiatives, and the relevant HTS data analysis techniques. Divided into three sections, in vitro assays, in vivo assays, and computational techniques to analyze HTS data are all examined. Written for the highly successful Methods in Molecular Biology series, most chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Автор: Janzen
Название: High Throughput Screening
ISBN: 1493936719 ISBN-13(EAN): 9781493936717
Издательство: Springer
Рейтинг:
Цена: 16769.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This third edition volumeexpands on the previous editions both by presenting more detailed protocols forthe techniques described in the first and second editions of High ThroughputScreening: Methods and Protocolsand by covering important new procedures. The first chapter ofthis book provides an overview of important assay development techniques, whilethe rest of the chapters detail how to develop and execute screens at whateverthroughput the user needs. Some chapter examples are: structure-based virtualscreening, high throughput screening using mass spectrometry, identification of state-dependentblockers for voltage gated calcium channels, bioluminescence resonanceenergy transfer platform to monitor protein-protein interactions in live cells,high throughput flow cytometry, and application of imaging-based assays in microplate formats for highcontent screening. Written in the highly successful Methods in MolecularBiology series format, chapters include introductions to their respectivetopics, lists of the necessary materials and reagents, step-by-step, readilyreproducible laboratory protocols, and tips on troubleshooting and avoidingknown pitfalls.Cutting edge and thorough, High Throughput Screening: Methods and Protocols,Third Edition, is a valuable resource for anyone who is interested in HTSresearch.

Автор: Michael Kahn
Название: High Throughput Screening for Novel Anti-Inflammatories
ISBN: 3764359129 ISBN-13(EAN): 9783764359126
Издательство: Springer
Рейтинг:
Цена: 30187.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Combinatorial chemistry in conjunction with High Throughput Screening (HTS) is revolutionizing the drug discovery process. This title includes chapters that represent the developments regarding the integration of combinatorial chemistry and HTS in connection with anti-inflammatory targets.