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Dynamic Analysis of Enzyme Systems, Katsuya Hayashi; Naoto Sakamoto


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Автор: Katsuya Hayashi; Naoto Sakamoto
Название:  Dynamic Analysis of Enzyme Systems
ISBN: 9783662115848
Издательство: Springer
Классификация:


ISBN-10: 3662115840
Обложка/Формат: Paperback
Страницы: 370
Вес: 0.52 кг.
Дата издания: 09.01.2013
Язык: English
Размер: 229 x 152 x 20
Основная тема: Life Sciences
Подзаголовок: An Introduction
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book is concerned with a quantitative analysis of dynamic behavior of various enzymatic reaction systems by computer simulation. The authors and coworkers have been engaged in cooperative research since 1975, seeking to clarify the catalytic and regulatory characteristics of enzymatic reactions in vivo and control mechanisms suitable for enzyme technology. Rather than enzyme kinetics generally known in enzymol- ogy, this research has employed an approach called enzyme dynamics which concentrates on the exact schematic representation of an actual reac- tion mechanism, derivation of rate equation on the basis of the scheme, and computer simulation of its dynamic behavior (numerical solution of the rate equation and explanation of kinetic and regulatory properties of the enzymatic reaction). A rate equation representing the behavior of enzymatic reactions is gen- erally expressed by a set of nonlinear differential equations. The analytic solution of rate equations is therefore impossible in general, making it necessary to introduce some approximations in order to analyze the exper- imental data in enzyme kinetics. For example, under an assumption of excess substrate against enzyme in a closed system, we commonly use the linear approximation for the early period of reaction, the quasi-steady- state approximation based on putative maintenance of steady state in en- zyme species, and the rapid-equilibrium approximation assuming instantane- ous equilibration in complex formation and between complexes. The kinetic characteristics obtained by these approximations do not always reflect the dynamic behavior of actual enzymatic reactions.


Enzyme Kinetics and Mechanism, Part F: Detection and Characteriza

Автор: Daniel L. Purich
Название: Enzyme Kinetics and Mechanism, Part F: Detection and Characteriza
ISBN: 0121822575 ISBN-13(EAN): 9780121822576
Издательство: Elsevier Science
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Цена: 25054.00 р.
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Описание: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with mo than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Protein Sensors and Reactive Oxygen Species, Part B: Thiol Enzyme

Автор: Helmut Sies
Название: Protein Sensors and Reactive Oxygen Species, Part B: Thiol Enzyme
ISBN: 0121822516 ISBN-13(EAN): 9780121822514
Издательство: Elsevier Science
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Цена: 25054.00 р.
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Описание: This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.

Fundamentals of Enzyme Kinetics, 4th Edition

Автор: Cornish-Bowden
Название: Fundamentals of Enzyme Kinetics, 4th Edition
ISBN: 3527330747 ISBN-13(EAN): 9783527330744
Издательство: Wiley
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Цена: 8078.00 р.
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Описание: Now in its fourth edition, this textbook is one of the few titles worldwide to cover enzyme kinetics in its entire scope and the only one to include its implications for bioinformatics and systems biology. Multi-enzyme complexes and cooperativity are therefore treated in more detail than in any other textbook on the market.

Fundamentals of Enzyme Engineering

Автор: Young Je Yoo; Yan Feng; Yong-Hwan Kim; Camila Flor
Название: Fundamentals of Enzyme Engineering
ISBN: 9402410244 ISBN-13(EAN): 9789402410242
Издательство: Springer
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Цена: 16769.00 р.
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Soil Enzymes. Influence of Sugar Industry Effluents on Soil Enzyme Activities

Автор: Maddela
Название: Soil Enzymes. Influence of Sugar Industry Effluents on Soil Enzyme Activities
ISBN: 3319426540 ISBN-13(EAN): 9783319426549
Издательство: Springer
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Цена: 7685.00 р.
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Описание: This book addresses issues arising from discharge of effluents from sugar industry on to surrounding land or into a water body such as physicochemical properties of soil, changes in the micro flora, quantification of soil enzyme activities as influenced by effluents. Disposal of effluents without neutralization has become general practice. These effluents are chemically heterogeneous, contain organic and inorganic pollutants including, sugar baggage, molasses, carbonates, bicarbonates. The impact of sugar industry effluents on microbial activities in terrestrial ecosystem is scanty. There is also significant interest in the study of soil enzymes because such effect reflects the potential capacity of a soil to perform certain biological transformation of soil fertility.

Dynamics in Enzyme Catalysis

Автор: Judith Klinman; Sharon Hammes- Schiffer
Название: Dynamics in Enzyme Catalysis
ISBN: 3642389619 ISBN-13(EAN): 9783642389610
Издательство: Springer
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Цена: 39130.00 р.
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Описание: Cindy Schulenburg and Donald Hilvert, Protein Conformational Disorder and Enzyme Catalysis. Brooks III, Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase.

Applications of Enzyme Biotechnology

Автор: Jeffrey W. Kelly; Thomas O. Baldwin
Название: Applications of Enzyme Biotechnology
ISBN: 1475792379 ISBN-13(EAN): 9781475792379
Издательство: Springer
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Цена: 26122.00 р.
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Описание: Proceedings of the Texas A&M University IUCCP Ninth Annual Symposium held in College Station, Texas, March 18-21, 1991.

Advances in Enzyme Biotechnology

Автор: Pratyoosh Shukla; Brett I. Pletschke
Название: Advances in Enzyme Biotechnology
ISBN: 813221093X ISBN-13(EAN): 9788132210931
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book covers the wide variety of enzymes in the field of enzyme biotechnology and details their industrial applications. It also includes new methods and state-of-the-art information on modern methods of enzyme discovery.

The Enzyme Catalysis Process

Автор: A. Cooper
Название: The Enzyme Catalysis Process
ISBN: 1475716095 ISBN-13(EAN): 9781475716092
Издательство: Springer
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Цена: 16979.00 р.
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Enzyme Handbook 9

Автор: Dietmar Schomburg; D?rte Stephan
Название: Enzyme Handbook 9
ISBN: 3642489877 ISBN-13(EAN): 9783642489877
Издательство: Springer
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Цена: 12157.00 р.
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Описание: Recent progress on enzyme immobilisation, enzyme production, coenzyme re- generation and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. The enzymes in this Handbook are arranged according to the Enzyme Com- mission list of enzymes.

Enzyme- and Transporter-Based Drug-Drug Interactions

Автор: K. Sandy Pang; A. David Rodrigues; Raimund M. Pete
Название: Enzyme- and Transporter-Based Drug-Drug Interactions
ISBN: 1489994890 ISBN-13(EAN): 9781489994899
Издательство: Springer
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Цена: 28732.00 р.
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Описание: This proceedings volume from the annual meeting of The American Association of Pharmaceutical Scientists, held November 2007, examines enzyme- and transporter-based DDIs that impact the absorption and disposition of drugs and impact on adverse outcomes.

Dynamics in Enzyme Catalysis

Автор: Judith Klinman; Sharon Hammes- Schiffer
Название: Dynamics in Enzyme Catalysis
ISBN: 3642440738 ISBN-13(EAN): 9783642440731
Издательство: Springer
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Цена: 27950.00 р.
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Описание: Christopher M. Cheatum and Amnon Kohen, Relationship of Femtosecond–Picosecond Dynamics to Enzyme-Catalyzed H-Transfer. Cindy Schulenburg and Donald Hilvert, Protein Conformational Disorder and Enzyme Catalysis. A. Joshua Wand, Veronica R. Moorman and Kyle W. Harpole, A Surprising Role for Conformational Entropy in Protein Function. Travis P. Schrank, James O. Wrabl and Vincent J. Hilser, Conformational Heterogeneity Within the LID Domain Mediates Substrate Binding to Escherichia coli Adenylate Kinase: Function Follows Fluctuations. Buyong Ma and Ruth Nussinov, Structured Crowding and Its Effects on Enzyme Catalysis. Michael D. Daily, Haibo Yu, George N. Phillips Jr and Qiang Cui, Allosteric Activation Transitions in Enzymes and Biomolecular Motors: Insights from Atomistic and Coarse-Grained Simulations. Karunesh Arora and Charles L. Brooks III, Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase. Steven D. Schwartz, Protein Dynamics and the Enzymatic Reaction Coordinate.


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