Tumor Suppressor Genes, Wafik S. El-Deiry

Автор: Gerard P. Zambetti
Название: The p53 Tumor Suppressor Pathway and Cancer
ISBN: 1489998799 ISBN-13(EAN): 9781489998798
Издательство: Springer
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Цена: 26120.00 р.
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Описание: The current year (2004) marks the Silver Anniversary of the discovery of the p53 tumor suppressor. Fueling the concept of p53 acting as a transforming factor, p53 expression was markedly elevated in various transformed and tumorigenic cell lines when compared to normal cells.

Автор: Hiroshi Maruta
Название: Tumor Suppressing Viruses, Genes, and Drugs,
ISBN: 0124762492 ISBN-13(EAN): 9780124762497
Издательство: Elsevier Science
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Цена: 16001.00 р.
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Описание: There has been increased focus on alternative treatments for cancer. This text presents the various cancer therapeutics that are being used or developed as a result of our knowledge about oncogenes, tumour suppressor genes and viral and non-viral replication.

Автор: David E. Fisher
Название: Tumor Suppressor Genes in Human Cancer
ISBN: 161737198X ISBN-13(EAN): 9781617371981
Издательство: Springer
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Цена: 34799.00 р.
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Описание: Leading-edge and forward-looking, Tumor Suppressor Genes in Human Cancer illuminates what is currently known of tumor suppressor genes and their regulation, work that is already beginning to revolutionize cancer target elucidation, drug discovery, and treatment design.

Автор: Escors, David Talmadge, James E. Breckpot, Karine Van Ginderachter, Jo A. Kochan, Grazyna
Название: Myeloid-derived suppressor cells and cancer
ISBN: 3319268198 ISBN-13(EAN): 9783319268194
Издательство: Springer
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Цена: 9141.00 р.
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Описание: The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting.

Автор: Tapas Mukhopadhyay; Steven A. Maxwell; Jack A. Rot
Название: p53 Suppressor Gene
ISBN: 3662222779 ISBN-13(EAN): 9783662222775
Издательство: Springer
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Цена: 15672.00 р.
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Описание: This book is about the p53 gene, one of the most frequently mutated or deleted genes in human cancers. The p53 protein is a transcription factor that can repress or activate promoters containing one of three p53 DNA-binding motifs. Replacement of the p53 function or restoration of the p53 biochemical pathway is a focus of gene therapy.

Автор: Dmitry I. Gabrilovich; Arthur Andrew Hurwitz
Название: Tumor-Induced Immune Suppression
ISBN: 1489980555 ISBN-13(EAN): 9781489980557
Издательство: Springer
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Цена: 28734.00 р.
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Описание: Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction.

Автор: Dmitry I. Gabrilovich; Arthur Andrew Hurwitz
Название: Tumor-Induced Immune Suppression
ISBN: 1441924000 ISBN-13(EAN): 9781441924001
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses new mechanisms that have never been discussed in a monograph before.

Автор: Peter D. Adams; John M. Sedivy
Название: Cellular Senescence and Tumor Suppression
ISBN: 1441910743 ISBN-13(EAN): 9781441910745
Издательство: Springer
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Цена: 26552.00 р.
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Описание: This book covers the latest findings in the link between cellular senescence and cancer including telemores and senescence signals, the senescent phenotype, and the physiological effects of senescence, including therapeutic applications.

Автор: Dmitry I. Gabrilovich; Arthur Andrew Hurwitz
Название: Tumor-Induced Immune Suppression
ISBN: 1493950517 ISBN-13(EAN): 9781493950515
Издательство: Springer
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Цена: 23508.00 р.
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Описание: Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction.

Автор: Peter D. Adams; John M. Sedivy
Название: Cellular Senescence and Tumor Suppression
ISBN: 1489983562 ISBN-13(EAN): 9781489983565
Издательство: Springer
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Цена: 23757.00 р.
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Описание: As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.