Targeted Cancer Treatment in Silico, Natalia L. Komarova; Dominik Wodarz
Автор: Burstein, Harold Название: Targeted therapies in breast cancer ISBN: 0199735670 ISBN-13(EAN): 9780199735679 Издательство: Oxford Academ Рейтинг: Цена: 2549.00 р. 3642.00-30% Наличие на складе: Есть (1 шт.) Описание: This book provides clinicians with ultra-concise, evidence-based current information and insight on implementing the latest treatment strategies, for treating breast cancer, including targeted agents, into clinical practice.
Автор: Manfred Dietel Название: Targeted Therapies in Cancer ISBN: 3642432433 ISBN-13(EAN): 9783642432439 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: From its introduction, oncological chemotherapy has been encumbered by its poor selectivity because most antiproliferative drugs are toxic not only to tumor cells but also to important populations of the body’s non-neoplastic cells. The resultant problems with unwanted side effects are compounded by difficulties in predicting the desired effectivity of chemotherapy in individual patients. This unsatisfactory situation has driven intensive research and development towards more specific and less toxic anticancer drugs over the last few decades. Several results of these efforts have reached the clinic and an even greater number are now in preclinical testing. Common to all these targeted therapies is their interaction with defined molecules present on cancer cells, which adds various degrees of increased selectivity to their toxic effects. As a consequence, detecting the target molecule on tumors before therapy holds great diagnostic potential for predicting the efficacy of the drug and personalizing therapy. This book aims to present translational scientists and clinicians with an integrated critical view on the theories, mechanisms, problems and pitfalls of the targeted therapy approach.
Автор: Francesco Colotta; Alberto Mantovani Название: Targeted Therapies in Cancer: ISBN: 1441925376 ISBN-13(EAN): 9781441925374 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This crucial text offers readers an overview of diverse approaches to targeted cancer therapies, ranging from drug discovery to cellular therapy. Overall, the book addresses the key question of whether ultimately targeted therapy in cancer will be a myth or a reality.
Автор: Varsha Gandhi; Kapil Mehta; Rajesh Grover; Sen Pat Название: Multi-Targeted Approach to Treatment of Cancer ISBN: 3319357689 ISBN-13(EAN): 9783319357683 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, clinicians and basic scientists from USA, India, and other countries discuss the rationales and clinical experiences with targeted approaches to treat, prevent, or manage cancer.
Автор: Natalia L. Komarova; Dominik Wodarz Название: Targeted Cancer Treatment in Silico ISBN: 1493942492 ISBN-13(EAN): 9781493942497 Издательство: Springer Рейтинг: Цена: 6567.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Countless medical researchers over the past century have been occupied by the search for a cure of cancer. So far, they have developed and implemented a wide range of treatment techniques, including surgery, chemo- and radiotherapy, antiangiogenic drugs, small molecule inhibitors, and oncolytic viruses. However, patterns of these treatments' effectiveness remain largely unclear, and a better understanding of how cancer therapies work has become a key research goal. Cancer Treatment in Silico provides the first in-depth study of approaching this understanding by modeling cancer treatments, both mathematically and through computer simulations. The main goal of this book is to help expose students and researchers to in silico methods of studying cancer. It is intended for both the applied mathematics and experimental oncology communities, as mathematical models are playing an increasingly important role to supplement laboratory biology in the fight against cancer. Written at a level that generally requires little technical background, the work will be a valuable resource for scientists and students alike.
Автор: Varsha Gandhi; Kapil Mehta; Rajesh Grover; Sen Pat Название: Multi-Targeted Approach to Treatment of Cancer ISBN: 3319122525 ISBN-13(EAN): 9783319122526 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, clinicians and basic scientists from USA, India, and other countries discuss the rationales and clinical experiences with targeted approaches to treat, prevent, or manage cancer.
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