Multi-Targeted Approach to Treatment of Cancer, Varsha Gandhi; Kapil Mehta; Rajesh Grover; Sen Pat
Автор: Varsha Gandhi; Kapil Mehta; Rajesh Grover; Sen Pat Название: Multi-Targeted Approach to Treatment of Cancer ISBN: 3319357689 ISBN-13(EAN): 9783319357683 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, clinicians and basic scientists from USA, India, and other countries discuss the rationales and clinical experiences with targeted approaches to treat, prevent, or manage cancer.
Автор: Natalia L. Komarova; Dominik Wodarz Название: Targeted Cancer Treatment in Silico ISBN: 1493942492 ISBN-13(EAN): 9781493942497 Издательство: Springer Рейтинг: Цена: 6567.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Countless medical researchers over the past century have been occupied by the search for a cure of cancer. So far, they have developed and implemented a wide range of treatment techniques, including surgery, chemo- and radiotherapy, antiangiogenic drugs, small molecule inhibitors, and oncolytic viruses. However, patterns of these treatments' effectiveness remain largely unclear, and a better understanding of how cancer therapies work has become a key research goal. Cancer Treatment in Silico provides the first in-depth study of approaching this understanding by modeling cancer treatments, both mathematically and through computer simulations. The main goal of this book is to help expose students and researchers to in silico methods of studying cancer. It is intended for both the applied mathematics and experimental oncology communities, as mathematical models are playing an increasingly important role to supplement laboratory biology in the fight against cancer. Written at a level that generally requires little technical background, the work will be a valuable resource for scientists and students alike.
Автор: Natalia L. Komarova; Dominik Wodarz Название: Targeted Cancer Treatment in Silico ISBN: 146148300X ISBN-13(EAN): 9781461483007 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an original look at the application of mathematical tools to specific questions in oncology. It presents mathematical methods most suitable for modeling different types of cancer treatment, from chemotherapy to antiangiogenic strategies.
Автор: Peter J. Houghton; Robert J. Arceci Название: Molecularly Targeted Therapy for Childhood Cancer ISBN: 148998142X ISBN-13(EAN): 9781489981424 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular `drivers` can be exploited from a therapeutic standpoint with currently available targeted agents.
Автор: Ann L. Jackman; Christopher P. Leamon Название: Targeted Drug Strategies for Cancer and Inflammation ISBN: 1489988866 ISBN-13(EAN): 9781489988867 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes progress in the use of folates to transport antifolate drugs such as raltitrexed and pemetrexed that block the mechanisms of cancer. Covers development of FR-targeted antifolate drugs and folate conjugates bearing a range of payloads (including cytotoxic drugs).
Автор: Joseph Lustgarten; Yan Cui; Shulin Li Название: Targeted Cancer Immune Therapy ISBN: 1493939912 ISBN-13(EAN): 9781493939916 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Stimulation of the immune system’s ability to control and destroy tumors cont- ues to be the goal of cancer immune therapy; but the scope has rapidly expanded; approaches are constantly updated; new molecules are continually introduced; and immune mechanisms are becoming better understood. This book has no intention of covering every aspect of immune therapy but rather focuses on the novelty of cancer immune therapy in an attempt to give readers an opportunity to absorb the new aspects of immune therapy from a single source. In this regard, three areas were selected: cytokine immune therapy, cell-based immune therapy, and targeted immune therapy. In each of these three sections, only the novel aspects of immune therapy were described instead of attempting to cover any historical achievement. In the first section, Cytokine Immune Therapy, the IL12 family, IL18, IL21, IL24, IL28, and IL29 were emphasized in regard to the an- tumor function and application in treating tumors. Most of these selected cyt- ines were discovered in last 10 years. In the second section, Cell-based Immune Therapy, the focus was engineering potent immune regulatory or effector cells such as dendritic cells, T cells, and stem cells. Cell engineering design is primarily based on the increased understanding of the interaction of tumor antigen-presenting cells, antigen- specific effector cells, and the tumor microenvironment.
Автор: Thomas Efferth Название: Resistance to Targeted ABC Transporters in Cancer ISBN: 3319379968 ISBN-13(EAN): 9783319379968 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This critical review volume explores the theme of ABC transporters in the context of basic cancer research and its role in drug-resistant tumors.
Описание: This book explores different approaches to develop phthalocyanine-based photosensitizers toward dual and targeted photodynamic therapy (PDT), with a view to improving their specific delivery to cancerous tissues and efficiency in PDT.
Автор: Ricardo H Alvarez; Javier Cort?s; Mary Falzon; Mic Название: Handbook of HER2-Targeted Agents in Breast Cancer ISBN: 331928214X ISBN-13(EAN): 9783319282145 Издательство: Springer Рейтинг: Цена: 8384.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This concise handbook provides oncologists and other healthcare providers with crucial updates in the field, including an updated review of the current understanding of the biology of the HER2 pathway, an overview of HER2-testing, and evidence-based discussions of available and emerging HER2-targeted treatment options.
Автор: Fazlul H. Sarkar Название: MicroRNA Targeted Cancer Therapy ISBN: 3319376063 ISBN-13(EAN): 9783319376066 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The most attractive feature of miRNAs is that one miRNA can regulate many target genes (mRNAs) and thus miRNA targeted therapy is highly promising because multiple genes could be regulated by targeting a single miRNA, which becomes very important for the killing of highly heterogeneous populations of cancer cells within a tumor mass.
Автор: Jenifer Prosperi Название: Resistance to Targeted Therapies in Breast Cancer ISBN: 331970141X ISBN-13(EAN): 9783319701417 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: We present an in-depth description of resistance to targeted therapies in breast cancer. Targeted therapies discussed here include those used to treat ER+ or Her2+ breast cancers (i.e., Tamoxifen or trastuzumab) or those targeting signaling pathways aberrantly activated in triple negative breast cancer (i.e., EGFR and Wnt signaling).
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