Extracellular Matrix for Tissue Engineering and Biomaterials, Anna C. Berardi

Автор: Elizabeth D. Hay
Название: Cell Biology of Extracellular Matrix
ISBN: 1461282268 ISBN-13(EAN): 9781461282266
Издательство: Springer
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Цена: 16979.00 р.
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Описание: At a recent meeting to discuss the domains of cell biology, I put forth a case for the extracellular matrix, even though my argument ran the risk of falling on deaf ears.

Автор: DeSimone Douglas W
Название: Extracellular Matrix in Development
ISBN: 3642359345 ISBN-13(EAN): 9783642359347
Издательство: Springer
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Цена: 26122.00 р.
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Описание: This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function.

Автор: Struther Arnott; D. A. Rees; E. R. Morris
Название: Molecular Biophysics of the Extracellular Matrix
ISBN: 1461295939 ISBN-13(EAN): 9781461295938
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Biopolymers, such as proteins and nucleic acids have been subjected to a rational succession of structural studies in which the determination of chemical compositions, link- ages, and sequences is followed by investigations of molecu- lar architecture and interactions. By the end of the 1960s the covalent structures of glycosaminoglycans and proteo- glycans had been defined both within the carbohydrate chains and in respect to their linkages to protein. The scene was therefore set for successful probing of three- dimensional shapes and intermolecular associations. For- tunately, during the 1970s appropriate physical methods were themselves greatly increasing in power. Consequently much progress has been made using X-ray diffraction anal- ysis of hydrated films, nuclear magnetic resonance spectro- scopy, and chromatographie methods for investigation of molecular interactions in solution. We now have a great deal of information about molecular shapes, their sensitiv- ity to environment (especially associated cations), and their modes of interaction that could be relevant to super- molecular assemblies in biological milieux. For these rea- sons we judged that it would be timely to distil the main conclusions from this phase of research to prepare for the next, which will involve detailed study of the interplay be- tween biological function and molecular structure. The idea for this volume emerged from a workshop meeting at Colworth sponsored by the Biochemical Society.

Автор: Fred W. Keeley; Robert Mecham
Название: Evolution of Extracellular Matrix
ISBN: 3642430376 ISBN-13(EAN): 9783642430374
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This volume examines how the major ECM components evolved over time to fill their specific roles found in modern organisms. Coverage includes structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes.

Автор: Schmuck
Название: Cardiac Extracellular Matrix
ISBN: 3319974203 ISBN-13(EAN): 9783319974200
Издательство: Springer
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Цена: 16070.00 р.
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Описание: This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM’s role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.

Автор: Douglas W. DeSimone; Robert Mecham
Название: Extracellular Matrix in Development
ISBN: 3642427405 ISBN-13(EAN): 9783642427404
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function.

Автор: Roy Zent; Ambra Pozzi
Название: Cell-Extracellular Matrix Interactions in Cancer
ISBN: 1489981128 ISBN-13(EAN): 9781489981127
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This book describes how extracellular matrix components (ECM) create a niche for tumor formation. It also discusses the contribution of ECM components and their respective receptors in the development and spread of cancer.

Автор: Robert Mecham
Название: The Extracellular Matrix: an Overview
ISBN: 364226719X ISBN-13(EAN): 9783642267192
Издательство: Springer
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Цена: 28732.00 р.
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Описание: Covering a wide spectrum of topics including collagen types and the role of the ECM in human disease and pathogenesis, this volume is a timely overview of the structure, regulation, and function of the major macromolecules that form the extracellular matrix.