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Cardiac Extracellular Matrix, Schmuck


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Цена: 16070.00р.
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Автор: Schmuck
Название:  Cardiac Extracellular Matrix
ISBN: 9783319974200
Издательство: Springer
Классификация:





ISBN-10: 3319974203
Обложка/Формат: Hardcover
Страницы: 269
Вес: 0.54 кг.
Дата издания: 2018
Серия: Advances in Experimental Medicine and Biology
Язык: English
Издание: 1st ed. 2018
Иллюстрации: 26 tables, color; 32 illustrations, color; 2 illustrations, black and white; iii, 269 p. 34 illus., 32 illus. in color.
Размер: 234 x 156 x 16
Читательская аудитория: Professional & vocational
Основная тема: Cell Biology
Подзаголовок: Fundamental Science to Clinical Applications
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM’s role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.
Дополнительное описание: Preface.- Biomechanical Properties and Mechanobiology of Cardiac ECM.- Imaging the Cardiac Extracellular Matrix.- Animal Models and Cardiac Extracellular Matrix Research.- Applications of Cardiac Extracellular Ma-trix in Tissue Engineering and Regenera-ti



Cell Biology of Extracellular Matrix

Автор: Elizabeth D. Hay
Название: Cell Biology of Extracellular Matrix
ISBN: 1461282268 ISBN-13(EAN): 9781461282266
Издательство: Springer
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Цена: 16979.00 р.
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Описание: At a recent meeting to discuss the domains of cell biology, I put forth a case for the extracellular matrix, even though my argument ran the risk of falling on deaf ears.

Extracellular Matrix in Tumor Biology

Автор: Rolf A. Brekken; Dwayne Stupack
Название: Extracellular Matrix in Tumor Biology
ISBN: 3319609068 ISBN-13(EAN): 9783319609065
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression.

Molecular Biophysics of the Extracellular Matrix

Автор: Struther Arnott; D. A. Rees; E. R. Morris
Название: Molecular Biophysics of the Extracellular Matrix
ISBN: 1461295939 ISBN-13(EAN): 9781461295938
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Biopolymers, such as proteins and nucleic acids have been subjected to a rational succession of structural studies in which the determination of chemical compositions, link- ages, and sequences is followed by investigations of molecu- lar architecture and interactions. By the end of the 1960s the covalent structures of glycosaminoglycans and proteo- glycans had been defined both within the carbohydrate chains and in respect to their linkages to protein. The scene was therefore set for successful probing of three- dimensional shapes and intermolecular associations. For- tunately, during the 1970s appropriate physical methods were themselves greatly increasing in power. Consequently much progress has been made using X-ray diffraction anal- ysis of hydrated films, nuclear magnetic resonance spectro- scopy, and chromatographie methods for investigation of molecular interactions in solution. We now have a great deal of information about molecular shapes, their sensitiv- ity to environment (especially associated cations), and their modes of interaction that could be relevant to super- molecular assemblies in biological milieux. For these rea- sons we judged that it would be timely to distil the main conclusions from this phase of research to prepare for the next, which will involve detailed study of the interplay be- tween biological function and molecular structure. The idea for this volume emerged from a workshop meeting at Colworth sponsored by the Biochemical Society.

Extracellular Matrix in Development

Автор: Douglas W. DeSimone; Robert Mecham
Название: Extracellular Matrix in Development
ISBN: 3642427405 ISBN-13(EAN): 9783642427404
Издательство: Springer
Рейтинг:
Цена: 22201.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function.

Evolution of Extracellular Matrix

Автор: Fred W. Keeley; Robert Mecham
Название: Evolution of Extracellular Matrix
ISBN: 3642430376 ISBN-13(EAN): 9783642430374
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This volume examines how the major ECM components evolved over time to fill their specific roles found in modern organisms. Coverage includes structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes.

Cell-Extracellular Matrix Interactions in Cancer

Автор: Roy Zent; Ambra Pozzi
Название: Cell-Extracellular Matrix Interactions in Cancer
ISBN: 1489981128 ISBN-13(EAN): 9781489981127
Издательство: Springer
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Цена: 22201.00 р.
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Описание: This book describes how extracellular matrix components (ECM) create a niche for tumor formation. It also discusses the contribution of ECM components and their respective receptors in the development and spread of cancer.

Extracellular Matrix for Tissue Engineering and Biomaterials

Автор: Anna C. Berardi
Название: Extracellular Matrix for Tissue Engineering and Biomaterials
ISBN: 3319770217 ISBN-13(EAN): 9783319770215
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This volume provides a state-of-art-report on the new methodologies in tissue engineering and developments in the biomaterials field based on the extracellular matrix-relevant discovery. Extracellular Matrix for Tissue Engineering and Biomaterials opens with an overview of the latest extracellular matrix research and in Part I, focuses on its biology and its role on cell behavior and cell fate relevant for the design of biomimetic surfaces. Part II details issues regarding the strategies currently applied in the research of biologically inspired materials and material systems for the replacement, repair and regeneration of tissues and organs. Part III presents the latest development methods applying knowledge from biology towards nanotechnology, to promote the restoration of the functionality of a living tissue. The book ranges from fundamental biology associated with tissue regeneration for the development of biomimetic approaches to controlling tissue formation, cell function, differentiation and angiogenesis using factors involved in normal tissue development and function. With the breadth and depth of the coverage of this topic, this book will serve as a valuable reference for anyone working in tissue engineering or biomaterials – from scientists, chemists and biologists through physicists, bioengineers and clinicians.

Mechanosensing and Mechanochemical Transduction in Extracellular Matrix

Автор: S.S. Cowin; Frederick H. Silver
Название: Mechanosensing and Mechanochemical Transduction in Extracellular Matrix
ISBN: 1489986162 ISBN-13(EAN): 9781489986160
Издательство: Springer
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Цена: 9794.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The only single authored text on biological polymers available for bioengineering and biomedical engineering students. The book describes the structure of polymers and how these molecules are put together to make the tissues of the body.

Extracellular Matrix in Development

Автор: DeSimone Douglas W
Название: Extracellular Matrix in Development
ISBN: 3642359345 ISBN-13(EAN): 9783642359347
Издательство: Springer
Рейтинг:
Цена: 26122.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function.

The Extracellular Matrix: an Overview

Автор: Robert Mecham
Название: The Extracellular Matrix: an Overview
ISBN: 364226719X ISBN-13(EAN): 9783642267192
Издательство: Springer
Рейтинг:
Цена: 28732.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Covering a wide spectrum of topics including collagen types and the role of the ECM in human disease and pathogenesis, this volume is a timely overview of the structure, regulation, and function of the major macromolecules that form the extracellular matrix.


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