Molecular Mechanisms of Body Water Homeostasis, Carolyn M. Ecelbarger, Dharmendra Kumar Chaudhary, Hwal Lee, Swasti Tiwari
Автор: Kelly Anne Hyndman; Thomas L. Pannabecker Название: Sodium and Water Homeostasis ISBN: 1493932128 ISBN-13(EAN): 9781493932122 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents cutting edge methods that provide insights into the pathways by which salt and water traverse cell membranes and flow in an orchestrated fashion amongst the many compartments of the body. It focuses on a number of molecular, cellular and whole animal studies that involve multiple physiological systems and shows how the internal milieu is regulated by multifactorial gene regulation, molecular signaling, and cell and organ architecture. Topics covered include: water channels, the urinary concentrating mechanism, angiotensin, the endothelin system, miRNAs and MicroRNA in osmoregulation, desert-adapted mammals, the giraffe kidney, mosquito Malpighian tubules, and circadian rhythms. The book highlights how different approaches to explaining the same physiological processes greatly increase our understanding of these fundamental processes. Greater integration of comparative, evolutionary and genetic animal models in basic science and medical science will improve our overall grasp of the mechanisms of sodium and water balance.
Описание: The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases.There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.
Описание: The evidence that these effects are mediated through the estrogen receptor(s) is based on similar but not always identical phenotypes as observed in experimental animal models of estrogen receptor mutations as well as the single clinical case of an estrogen receptor alpha mutant patient.
Автор: Ingrid C. Gelissen; Andrew J. Brown Название: Cholesterol Homeostasis ISBN: 1493968734 ISBN-13(EAN): 9781493968732 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides state-of-the-art techniques for studying various aspects of cholesterol homeostasis, including its uptake, synthesis and efflux from the cell, as well as its trafficking within the cell.
Автор: Nektarios Tavernarakis Название: Protein Metabolism and Homeostasis in Aging ISBN: 1489979395 ISBN-13(EAN): 9781489979391 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines the role of protein metabolism and homeostasis in aging. It offers an overview of the current knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, and degradation and turnover.
Автор: Yuzuru Ishimura; Hideo Shimada; Makoto Suematsu Название: Oxygen Homeostasis and Its Dynamics ISBN: 4431684786 ISBN-13(EAN): 9784431684787 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first volume in a projected series contains the proceedings of the first of the Keio University International Symposia for Life Sciences and Medicine under the sponsorship of the Keio University Medical Science Fund.
Автор: Keith Schillo Название: Human Anatomy and Physiology: Form, Function, and Homeostasis ISBN: 151652957X ISBN-13(EAN): 9781516529575 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 27582.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Human Anatomy and Physiology: Form, Function, and Homeostasis helps students understand the human body in terms of the structures and functions of various body systems. Clear and concise, the selected material provides descriptions of how major organ systems, individual organs, tissues, and cells interact to maintain homeostasis. The text establishes a conceptual framework for studying anatomy and physiology at the molecular, cellular, and systematic levels. The major chapters of the text include the integumentary, skeletal, muscular, nervous, endocrine, cardiovascular, respiratory, digestive, urinary, and reproductive systems. Chapters that focus on physiology begin with case studies that highlight major concepts and progress to discussions of the major processes that regulate homeostasis. All chapters include a list of learning outcomes that are aligned with a collection of study questions. Many standard texts provide more information than can be covered, even in a standard, two-course progression. Human Anatomy and Physiology streamlines information and focuses on the most important aspects of human form and function in a no-frills, non-intimidating manner. The book is specifically designed for standard two-course sequences in anatomy and physiology, and is best suited to students who have completed a semester of biology.
Автор: E. Carafoli; J. Krebs Название: Calcium Homeostasis ISBN: 3642635326 ISBN-13(EAN): 9783642635328 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Danielle Pansu; Felix Bronner Название: Calcium Transport and Intracellular Calcium Homeostasis ISBN: 3642839797 ISBN-13(EAN): 9783642839795 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop on Calcium Transport and Intracellular Calcium Homeostasis held in Lyon, France, March 4-7, 1990
Автор: Yuzuru Ishimura; Hideo Shimada; Makoto Suematsu Название: Oxygen Homeostasis and Its Dynamics ISBN: 4431702024 ISBN-13(EAN): 9784431702023 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first volume in a projected series contains the proceedings of the first of the Keio University International Symposia for Life Sciences and Medicine under the sponsorship of the Keio University Medical Science Fund.
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