Описание: Focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book explains how to identify cardiovascular pathologies and compare with normal physiology to aid research. It gives concise explanations of key issues and background reading suggestions.
Автор: Stephen T. Sonis; Dorothy M. Keefe Название: Pathobiology of Cancer Regimen-Related Toxicities ISBN: 1489990704 ISBN-13(EAN): 9781489990709 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book defines the scope, impact and behavior of cancer regimen-related toxicities and frames the balance between treatment success and physiological cost. Covers pathobiology of common toxicities and strategies for development of effective interventions.
Описание: This book encompasses a decade of explosive growth in knowledge of the pathobiology of hematologic cancer, and offers the insight of experts from around the world on current treatment approaches and on future progress in malignant hematologic diseases.
Автор: Roy Zent; Ambra Pozzi Название: Cell-Extracellular Matrix Interactions in Cancer ISBN: 1489981128 ISBN-13(EAN): 9781489981127 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes how extracellular matrix components (ECM) create a niche for tumor formation. It also discusses the contribution of ECM components and their respective receptors in the development and spread of cancer.
Автор: Schmuck Название: Cardiac Extracellular Matrix ISBN: 3319974203 ISBN-13(EAN): 9783319974200 Издательство: Springer Рейтинг: Цена: 16070.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM’s role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal models of cardiac research, tracking and imaging methods of cardiac ECM, and cGMP manufacturing and regulatory considerations for ECM based therapeutics. Finally, the third section, Clinical Applications, will highlight the clinical experience around cardiac ECM including therapeutic strategies targeting scar tissue in the heart, Clinical trial design and regulatory considerations, current human clinical trials in cardiovascular medicine and the role of pharmaceutical and biotech companies in the commercialization of ECM technologies for cardiovascular indications. This book provides a comprehensive review for basic and translational researchers as well as clinical practitioners and those involved in commercialization, regulatory and entrepreneurial activities.
Автор: Anna C. Berardi Название: Extracellular Matrix for Tissue Engineering and Biomaterials ISBN: 3319770217 ISBN-13(EAN): 9783319770215 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides a state-of-art-report on the new methodologies in tissue engineering and developments in the biomaterials field based on the extracellular matrix-relevant discovery. Extracellular Matrix for Tissue Engineering and Biomaterials opens with an overview of the latest extracellular matrix research and in Part I, focuses on its biology and its role on cell behavior and cell fate relevant for the design of biomimetic surfaces. Part II details issues regarding the strategies currently applied in the research of biologically inspired materials and material systems for the replacement, repair and regeneration of tissues and organs. Part III presents the latest development methods applying knowledge from biology towards nanotechnology, to promote the restoration of the functionality of a living tissue. The book ranges from fundamental biology associated with tissue regeneration for the development of biomimetic approaches to controlling tissue formation, cell function, differentiation and angiogenesis using factors involved in normal tissue development and function. With the breadth and depth of the coverage of this topic, this book will serve as a valuable reference for anyone working in tissue engineering or biomaterials – from scientists, chemists and biologists through physicists, bioengineers and clinicians.
Автор: Douglas W. DeSimone; Robert Mecham Название: Extracellular Matrix in Development ISBN: 3642427405 ISBN-13(EAN): 9783642427404 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function.
Автор: Robert Mecham Название: The Extracellular Matrix: an Overview ISBN: 364226719X ISBN-13(EAN): 9783642267192 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Covering a wide spectrum of topics including collagen types and the role of the ECM in human disease and pathogenesis, this volume is a timely overview of the structure, regulation, and function of the major macromolecules that form the extracellular matrix.
Автор: Mecham, Robert Название: Methods in Extracellular Matrix Biology ISBN: 0128122978 ISBN-13(EAN): 9780128122976 Издательство: Elsevier Science Рейтинг: Цена: 23412.00 р. Наличие на складе: Поставка под заказ.
Описание:
Methods in Extra Cellular Matrix, Volume 142, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections devoted to Elastin, Quantification of collagen and elastin, Fibrillins, Lysyl oxidase, Fibulins, Matrilins, Hyaluronic Acid, Small leucine-rich proteoglycans, Syndecans, Fibronectin, SPARC, Thrombospondins, Tenascins, Collagen IV, Multi-photon analysis of ECM, Cell-derived extracellular matrices, Laminins, Fibrillar Collagens, Imaging ECM in developing embryos, Analysis of Matrix Degradation, Ultrastructural analysis of ECM, Versican and Large proteoglycans, and an ECM crosslink analysis.
This series covers a wide array of topics about the extracellular matrix, including an understanding of crucial proteins and glycoproteins components of ECM.
Contains contributions from experts in the field from across the world
Covers a wide array of topics on the extracellular matrix, including an understanding crucial proteins and the glycoproteins components of ECM
Includes analysis based topics, such as quantification of collagen and elastin, mulit-photon analysis of ECM and ECM crosslink analysis
Vascular Pharmacology: Cytoskeleton and Extracellular Matrix, Volume 81, contains the latest information on the vascular cytoskeleton and extracellular matrix that is presented with helpful illustrations and supporting references by prominent scientists and highly-recognized experts in the vascular field. Topics of interest in this new release include Pharmacology of the Vascular Cytoskeleton and Extracellular Matrix, The Dynamic Actin Cytoskeleton in Smooth Muscle, The Role of the Actin Cytoskeleton in the Regulation of Vascular Inflammation, The Smoothelin Family of Proteins and the Smooth Muscle Cell Contractile Apparatus, Smooth Muscle Cytoskeletal Network Regulates Expression of the Profibrotic Genes PAI-1 and CTGF, and more.
Presents a must-read book on the vascular cytoskeleton and extracellular matrix
Contains up-to-date information on the structure, function and development of the vascular cell cytoskeleton
Includes contributors from prominent scientists and highly-recognized experts with major accomplishments in the fields of the vascular cytoskeleton, extracellular matrix, mechanotransduction and vascular remodeling
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