Multiscale Mechanobiology of Bone Remodeling and Adaptation, Peter Pivonka
Автор: Amit Gefen; Dafna Benayahu Название: The Mechanobiology of Obesity and Related Diseases ISBN: 3319093355 ISBN-13(EAN): 9783319093352 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mechanical behavior and properties of adipose tissue.- Mathematical models of adipose tissue dynamics.- Mechanical stretching and signaling pathways in adipogenesis- Role of mechanical stimulations in directing mesenchymal stem cell adipogenesis.- The vicious cycle of estrogen consumption and obesity: The role of mechanotransduction.- Extracellular matrix remodeling and mechanical stresses as modulators of adipose tissue metabolism and inflammation.- The Impact of Obesity and Weight Loss on Gait in Adults.- Excessive Weight Bearing Compromises Foot Structure and Function across the Lifespan.- Obesity, Osteoarthritis and Aging: The Biomechanical Links.- Impaired neutrophil mechanoregulation by fluid flow: A potential contributing factor for microvascular dysfunction in obesity.- Mechanotransduction and the myogenic response in diabetes.- Role of adipose cells in tumor microenvironment.
Автор: Siegfried Schmauder, Immanuel Sch?fer Название: Multiscale Materials Modeling: Approaches to Full Multiscaling ISBN: 3110412365 ISBN-13(EAN): 9783110412369 Издательство: Walter de Gruyter Цена: 22305.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents current spatial and temporal multiscaling approaches of materials modeling. Recent results demonstrate the deduction of macroscopic properties at the device and component level by simulating structures and materials sequentially on atomic, micro- and mesostructural scales. The book covers precipitation strengthening and fracture processes in metallic alloys, materials that exhibit ferroelectric and magnetoelectric properties as well as biological, metal-ceramic and polymer composites. The progress which has been achieved documents the current state of art in multiscale materials modelling (MMM) on the route to full multi-scaling. Contents:Part I: Multi-time-scale and multi-length-scale simulations of precipitation and strengthening effectsLinking nanoscale and macroscaleMultiscale simulations on the coarsening of Cu-rich precipitates in ?-Fe using kinetic Monte Carlo, Molecular Dynamics, and Phase-Field simulationsMultiscale modeling predictions of age hardening curves in Al-Cu alloysKinetic Monte Carlo modeling of shear-coupled motion of grain boundariesProduct Properties of a two-phase magneto-electric compositePart II: Multiscale simulations of plastic deformation and fractureNiobium/alumina bicrystal interface fractureAtomistically informed crystal plasticity model for body-centred cubic ironFE2AT ? finite element informed atomistic simulationsMultiscale fatigue crack growth modeling for welded stiffened panelsMolecular dynamics study on low temperature brittleness in tungsten single crystalsMulti scale cellular automata and finite element based model for cold deformation and annealing of a ferritic-pearlitic microstructureMultiscale simulation of the mechanical behavior of nanoparticle-modified polyamide compositesPart III: Multiscale simulations of biological and bio-inspired materials, bio-sensors and compositesMultiscale Modeling of Nano-BiosensorsFinite strain compressive behaviour of CNT/epoxy nanocompositesPeptide?zinc oxide interaction
Автор: Peter Pivonka Название: Multiscale Mechanobiology of Bone Remodeling and Adaptation ISBN: 3319588435 ISBN-13(EAN): 9783319588438 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors.Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.
Автор: Damien Lacroix; Marzia Brunelli; C?cile Perrault; Название: Multiscale Mechanobiology in Tissue Engineering ISBN: 9811340560 ISBN-13(EAN): 9789811340567 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.
Автор: Gerhard A. Holzapfel; Raymond W. Ogden Название: Multiscale Soft Tissue Mechanics and Mechanobiology ISBN: 9402415122 ISBN-13(EAN): 9789402415124 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Поставка под заказ.
Описание: This volume covers aspects of multiscale modeling of the mechanics and mechanobiology of soft biological tissues. The individual contributions focus on the constitutive modeling from the micro to the macro level in addition to computational modeling and simulation. It consists of peer-reviewed papers written by leading international authorities and will serve as a major state-of-the-art source of reference for the next few years. It includes both review articles and original articles. Previously published in the Journal of Elasticity, Volume 129, Issue 1-2, December 2017.
Автор: Suvranu De; Wonmuk Hwang; Ellen Kuhl Название: Multiscale Modeling in Biomechanics and Mechanobiology ISBN: 1447172299 ISBN-13(EAN): 9781447172291 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms.
Автор: Amit Gefen; Dafna Benayahu Название: The Mechanobiology of Obesity and Related Diseases ISBN: 3319376268 ISBN-13(EAN): 9783319376264 Издательство: Springer Рейтинг: Цена: 14365.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mechanical behavior and properties of adipose tissue.- Mathematical models of adipose tissue dynamics.- Mechanical stretching and signaling pathways in adipogenesis- Role of mechanical stimulations in directing mesenchymal stem cell adipogenesis.- The vicious cycle of estrogen consumption and obesity: The role of mechanotransduction.- Extracellular matrix remodeling and mechanical stresses as modulators of adipose tissue metabolism and inflammation.- The Impact of Obesity and Weight Loss on Gait in Adults.- Excessive Weight Bearing Compromises Foot Structure and Function across the Lifespan.- Obesity, Osteoarthritis and Aging: The Biomechanical Links.- Impaired neutrophil mechanoregulation by fluid flow: A potential contributing factor for microvascular dysfunction in obesity.- Mechanotransduction and the myogenic response in diabetes.- Role of adipose cells in tumor microenvironment.
Автор: Tim McGloughlin Название: Biomechanics and Mechanobiology of Aneurysms ISBN: 3642270751 ISBN-13(EAN): 9783642270758 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book offers new insights into aneurysm aetiology and behavior based on the most recent biomechanics research related to this important topic. It details key factors influencing aneurysm behavior and treatment.
Название: Mechanobiology Handbook ISBN: 1138072265 ISBN-13(EAN): 9781138072268 Издательство: Taylor&Francis Рейтинг: Цена: 16078.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mechanobiology--the study of the effects of mechanical environments on the biological processes of cells--has evolved from traditional biomechanics via the incorporation of strong elements of molecular and cell biology. Currently, a broad range of organ systems are being studied by surgeons, physicians, basic scientists, and engineers. These mechanobiologists aim to create new therapies and further biological understanding by quantifying the mechanical environment of cells and the molecular mechanisms of mechanically induced pathological conditions.
To achieve these goals, investigators must be familiar with both the basic concepts of mechanics and the modern tools of cellular/molecular biology. Unfortunately, current literature contains numerous studies that misuse standard mechanical estimations and terminology, or fail to implement appropriate molecular analyses. Therefore, the Mechanobiology Handbook not only presents cutting-edge research findings across various fields and organ systems, but also provides the elementary chapters on mechanics and molecular analysis techniques to encourage cross-field understanding and appropriate planning.
Aided by the continuous advancement of research tools in both mechanics and biology, more sophisticated experiments and analyses are possible--thus fueling the growth of the field of mechanobiology. Considering the complexity of the mechanics and the biology of the human body, most of the world of biomechanics remains to be studied. Since the field is still developing, the Mechanobiology Handbook does not force one unified theory, but brings out many different viewpoints and approaches to stimulate further research questions.
Автор: Yanhang Zhang Название: Multi-scale Extracellular Matrix Mechanics and Mechanobiology ISBN: 3030201813 ISBN-13(EAN): 9783030201814 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.
Автор: Xia Liang Название: Multiscale Structural Topology Optimization ISBN: 1785481002 ISBN-13(EAN): 9781785481000 Издательство: Elsevier Science Рейтинг: Цена: 11620.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Multiscale Structural Topology Optimization discusses the development of a multiscale design framework for topology optimization of multiscale nonlinear structures. With the intention to alleviate the heavy computational burden of the design framework, the authors present a POD-based adaptive surrogate model for the RVE solutions at the microscopic scale and make a step further towards the design of multiscale elastoviscoplastic structures. . Various optimization methods for structural size, shape, and topology designs have been developed and widely employed in engineering applications. Topology optimization has been recognized as one of the most effective tools for least weight and performance design, especially in aeronautics and aerospace engineering. . This book focuses on the simultaneous design of both macroscopic structure and microscopic materials. In this model, the material microstructures are optimized in response to the macroscopic solution, which results in the nonlinearity of the equilibrium problem of the interface of the two scales. The authors include a reduce database model from a set of numerical experiments in the space of effective strain.
Описание: Although there have been qualitative reports on the physiological incongruity of human joints, its effects on load transmission and subchondral bone density have remained incompletely characterized. This work reviews existing literature and to quantitatively assess the effect of incongruity on load transmission and subchondral mineralisation.
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