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Membrane Proteins in Aqueous Solutions, Jean-Luc Popot


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Автор: Jean-Luc Popot
Название:  Membrane Proteins in Aqueous Solutions
ISBN: 9783030103248
Издательство: Springer
Классификация:






ISBN-10: 3030103242
Обложка/Формат: Soft cover
Страницы: 708
Вес: 1.38 кг.
Дата издания: 2019
Серия: Biological and Medical Physics, Biomedical Engineering
Язык: English
Издание: Softcover reprint of
Иллюстрации: 353 tables, color; 266 illustrations, color; 171 illustrations, black and white; xxvii, 708 p. 437 illus., 266 illus. in color.
Размер: 254 x 178 x 37
Читательская аудитория: General (us: trade)
Ключевые слова: Biological and Medical Physics, Biophysics
Основная тема: Physics
Подзаголовок: From Detergents to Amphipols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book is the first to be entirely devoted to the challenging art of handling membrane proteins out of their natural environment, a key process in biological and pharmaceutical research, but one plagued with difficulties and pitfalls. Written by one of the foremost experts in the field, Membrane Proteins in Aqueous Solutions is accessible to any member of a membrane biology laboratory. After presenting the structure, functions, dynamics, synthesis, natural environment and lipid interactions of membrane proteins, the author discusses the principles of extracting them with detergents, the mechanisms of detergent-induced destabilization, countermeasures, and recent progress in developing detergents with weaker denaturing properties. Non-conventional alternatives to detergents, including bicelles, nanodiscs, amphipathic peptides, fluorinated surfactants and amphipols, are described, and their relative advantages and drawbacks are compared. The synthesis and solution properties of the various types of amphipols are presented, as well as the formation and properties of membrane protein/amphipol complexes and the transfer of amphipol-trapped proteins to detergents, nanodiscs, lipidic mesophases, or living cells. The final chapters of the book deal with applications: membrane protein in vitro folding and cell-free expression, solution studies, NMR, crystallography, electron microscopy, mass spectrometry, amphipol-mediated immobilization of membrane proteins, and biomedical applications.Important features of the book include introductory sections describing foundations as well as the state-of-the-art for each of the biophysical techniques discussed, and topical tables which organize a widely dispersed literature. Boxes and annexes throughout the book explain technical aspects, and twelve detailed experimental protocols, ranging from in vitro folding of membrane proteins to single-particle electron cryomicroscopy, have been contributed by and commented on by experienced users.Membrane Proteins in Aqueous Solutions offers a concise, accessible introduction to membrane protein biochemistry and biophysics, as well as comprehensive coverage of the properties and uses of conventional and non-conventional surfactants. It will be useful both in basic and applied research laboratories and as a teaching aid for students, instructors, researchers, and professionals within the field.

Дополнительное описание: From the Contents: Membrane proteins: functions, structures, environments.- Taking membrane proteins out of their natural environment.- Alternatives to detergents for handling membrane proteins in aqueous solutions.- Chemical structure and physical-chemic



Aqueous Solutions of Simple Electrolytes

Автор: Felix Franks
Название: Aqueous Solutions of Simple Electrolytes
ISBN: 1468429574 ISBN-13(EAN): 9781468429572
Издательство: Springer
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Цена: 14365.00 р.
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Описание: The chapters making up this volume had originally been planned to form part of a single volume covering solid hydrates and aqueous solutions of simple molecules and ions.

Membrane Proteins in Aqueous Solutions

Автор: Popot
Название: Membrane Proteins in Aqueous Solutions
ISBN: 3319731467 ISBN-13(EAN): 9783319731469
Издательство: Springer
Рейтинг:
Цена: 23058.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book is the first to be entirely devoted to the challenging art of handling membrane proteins out of their natural environment, a key process in biological and pharmaceutical research, but one plagued with difficulties and pitfalls. Written by one of the foremost experts in the field, Membrane Proteins in Aqueous Solutions is accessible to any member of a membrane biology laboratory. After presenting the structure, functions, dynamics, synthesis, natural environment and lipid interactions of membrane proteins, the author discusses the principles of extracting them with detergents, the mechanisms of detergent-induced destabilization, countermeasures, and recent progress in developing detergents with weaker denaturing properties. Non-conventional alternatives to detergents, including bicelles, nanodiscs, amphipathic peptides, fluorinated surfactants and amphipols, are described, and their relative advantages and drawbacks are compared. The synthesis and solution properties of the various types of amphipols are presented, as well as the formation and properties of membrane protein/amphipol complexes and the transfer of amphipol-trapped proteins to detergents, nanodiscs, lipidic mesophases, or living cells. The final chapters of the book deal with applications: membrane protein in vitro folding and cell-free expression, solution studies, NMR, crystallography, electron microscopy, mass spectrometry, amphipol-mediated immobilization of membrane proteins, and biomedical applications.Important features of the book include introductory sections describing foundations as well as the state-of-the-art for each of the biophysical techniques discussed, and topical tables which organize a widely dispersed literature. Boxes and annexes throughout the book explain technical aspects, and twelve detailed experimental protocols, ranging from in vitro folding of membrane proteins to single-particle electron cryomicroscopy, have been contributed by and commented on by experienced users.Membrane Proteins in Aqueous Solutions offers a concise, accessible introduction to membrane protein biochemistry and biophysics, as well as comprehensive coverage of the properties and uses of conventional and non-conventional surfactants. It will be useful both in basic and applied research laboratories and as a teaching aid for students, instructors, researchers, and professionals within the field.

Surface  tension and related thermodynamic quantities of aqueous electrolyte solutions

Автор: Matubayasi, Norihiro
Название: Surface tension and related thermodynamic quantities of aqueous electrolyte solutions
ISBN: 0367379473 ISBN-13(EAN): 9780367379476
Издательство: Taylor&Francis
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Цена: 9798.00 р.
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Описание:

Surface tension provides a thermodynamic avenue for analyzing systems in equilibrium and formulating phenomenological explanations for the behavior of constituent molecules in the surface region. While there are extensive experimental observations and established ideas regarding desorption of ions from the surfaces of aqueous salt solutions, a more successful discussion of the theory has recently emerged, which allows the quantitative calculation of the distribution of ions in the surface region. Surface Tension and Related Thermodynamic Quantities of Aqueous Electrolyte Solutions provides a detailed and systematic analysis of the properties of ions at the air/water interface.

Unifying older and newer theories and measurements, this book emphasizes the contributions of simple ions to surface tension behavior, and the practical consequences. It begins with a general discussion on Gibbs surface thermodynamics, offering a guide to his theoretical insight and formulation of the boundary between fluids. The text then discusses the thermodynamic formulae that are useful for practical experimental work in the analysis of fluid/fluid interfaces.

Chapters cover surface tension of pure water at air/water and air/oil interfaces, surface tension of solutions and the thermodynamic quantities associated with the adsorption and desorption of solutes, and surface tension of simple salt solutions. They also address adsorption of ions at the air/water interface, surface tension of solutions and the effect of temperature, adsorption from mixed electrolyte solutions, and thermodynamic properties of zwitterionic amino acids in the surface region. Focusing on the thermodynamic properties of ions at air/fluid interfaces, this book gives scientists a quantitative, rigorous, and objectively experimental methodology they can employ in their research.

An Introduction to Aqueous Electrolyte Solutions

Автор: Wright
Название: An Introduction to Aqueous Electrolyte Solutions
ISBN: 0470842946 ISBN-13(EAN): 9780470842942
Издательство: Wiley
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Цена: 10605.00 р.
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Описание: An introductory yet rigorous account of electrolyte solutions which emphasises the connection between the observable macroscopic experimental properties and the interpretations made at the molecular level.

CRC Handbook of Phase Equilibria and Thermodynamic Data of Aqueous Polymer Solutions

Автор: Wohlfarth, Christian
Название: CRC Handbook of Phase Equilibria and Thermodynamic Data of Aqueous Polymer Solutions
ISBN: 1138374733 ISBN-13(EAN): 9781138374737
Издательство: Taylor&Francis
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Цена: 9492.00 р.
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Описание:

A large amount of experimental data has been published since the debut of the original CRC Handbook of Thermodynamic Data of Aqueous Polymer Solutions. Incorporating new and updated material, the CRC Handbook of Phase Equilibria and Thermodynamic Data of Aqueous Polymer Solutions provides a comprehensive collection of thermodynamic data of polymer solutions. It helps readers quickly retrieve necessary information from the literature, and assists researchers in planning new measurements where data are missing.

A valuable resource for the modern chemistry field, the Handbook clearly details how measurements were conducted and methodically explains the nomenclature. It presents data essential for the production and use of polymers as well as for understanding the physical behavior and intermolecular interactions in polymer solutions.

Adsorption From Aqueous Solutions

Автор: P.H. Tewari
Название: Adsorption From Aqueous Solutions
ISBN: 1461332664 ISBN-13(EAN): 9781461332664
Издательство: Springer
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Цена: 12157.00 р.
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Описание: Adsorption from aqueous solutions is important in many tech- nological areas, like water purification, mineral beneficiation, soil conservation, detergency, and many areas of biology.

The Physics and Chemistry of Aqueous Ionic Solutions

Автор: M.C. Bellissent-Funel; G.W. Neilson
Название: The Physics and Chemistry of Aqueous Ionic Solutions
ISBN: 9401082367 ISBN-13(EAN): 9789401082365
Издательство: Springer
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Цена: 12157.00 р.
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Описание: Proceedings of the NATO Advanced Study Institute, Cargese, Corsica, France, June 22-July 5, 1986

Molecular Theory Of Water And Aqueous Solutions - Part Ii: The Role Of Water In Protein Folding, Self-Assembly And Molecular Recognition

Автор: Ben-Naim Arieh
Название: Molecular Theory Of Water And Aqueous Solutions - Part Ii: The Role Of Water In Protein Folding, Self-Assembly And Molecular Recognition
ISBN: 9814350532 ISBN-13(EAN): 9789814350532
Издательство: World Scientific Publishing
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Цена: 23760.00 р.
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Описание: Starts out by presenting the evidence for hydrophilic interactions in biochemical processes and then goes on to describe the applications of the hydrophilic interactions in these processes, specifically protein folding, protein association, self assembly and molecular recognition.

Water in Crystalline Hydrates Aqueous Solutions of Simple Nonelectrolytes

Автор: Felix Franks
Название: Water in Crystalline Hydrates Aqueous Solutions of Simple Nonelectrolytes
ISBN: 1475769601 ISBN-13(EAN): 9781475769609
Издательство: Springer
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Цена: 15672.00 р.
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Описание: . . . . . . . `. . . . . . . . . . . . xvi . . . . Contents of Volume 4 . . . . . . . . . . . . . . . . . . . . . . . . . . . xvii . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 . . . .

Metal Complexes in Aqueous Solutions

Автор: Arthur E. Martell; Robert D. Hancock
Название: Metal Complexes in Aqueous Solutions
ISBN: 0306452480 ISBN-13(EAN): 9780306452482
Издательство: Springer
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Цена: 20896.00 р.
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Описание: Details research on the formation and stabilities of metal complexes, chelates, macrocyclic complexes, and cryptates in aqueous solutions. This work includes chapters that describe the principles of ligand design and their application to a variety of metal ions. It also examines medicinal and biochemical applications of metal complexes.


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