Metabolic Network Reconstruction and Modeling, Marco Fondi
Автор: Gregory Stephanopoulos Название: Metabolic Engineering, ISBN: 0126662606 ISBN-13(EAN): 9780126662603 Издательство: Elsevier Science Рейтинг: Цена: 25054.00 р. Наличие на складе: Нет в наличии.
Описание:
Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes.
Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems.
Автор: Marco Fondi Название: Metabolic Network Reconstruction and Modeling ISBN: 1493975277 ISBN-13(EAN): 9781493975273 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume looks at the latest methodologies used to study cellular metabolism with in silico approaches. The chapters in this book are divided into 3 parts: part I discusses tools and methods used for metabolic reconstructions and basic constraint-based metabolic modeling (CBMM); Part II explores protocols for the generation of experimental data for metabolic reconstruction and modeling, including transcriptomics, proteomics, and mutant generations; and Part III cover advanced techniques for quantitative modeling of cellular metabolism, including dynamic Flux Balance Analysis and multi-objective optimization. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Metabolic Network Reconstruction and Modeling: Methods and Protocols is a valuable resource for qualified investigators studying cellular metabolism, and novice researchers who want to start working with CBMM.
Описание: Fall-induced hip fracture is an epidemic health risk among elderly people. This book presents an image-based multilevel modeling approach to understanding the biomechanics involved in fall-induced hip fracture. By hierarchically integrating a body-level dynamics model, a femur-level finite element model, and a local bone failure model, the biomechanics approach is able to simulate all stages in sideways falls and to incorporate all biomechanical variables affecting hip fracture.
This book is useful for clinicians to accurately evaluate fracture risk, for biomechanical engineers to virtually test hip protective devices, and for biomedical students to learn image-based biomechanical modeling techniques. This book also covers:Biomechanical viewing on bone composition, bone remodeling, and bone strengthBone imaging and information captured for constructing biomechanical modelsBone mechanical testing and mechanical properties required for biomechanical modeling
Synthetic Biology and Metabolic Engineering in Plants and Microbes: Part A," the new volume in the "Methods in Enzymology" series, " "continues the legacy of this premier serial with quality chapters authored by leaders in the field.
This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Contains two volumes covering research methods in synthetic biology and metabolic engineering in plants and microbesPresents sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways
Описание: This book reviews and discusses knowledge gathered on Metabolic Syndrome and analyzes the interplay between oxidative stress, chronic inflammation and angiogenesis features. It focuses on recent discoveries and progress toward possible therapeutic strategies.
Автор: Cortassa Sonia Del Carmen & Aon Miguel Antonio Et Название: Introduction To Metabolic And Cellular Engineering, An (Second Edition) ISBN: 9814365718 ISBN-13(EAN): 9789814365710 Издательство: World Scientific Publishing Рейтинг: Цена: 15840.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Metabolic and Cellular Engineering (MCE) is more than a scientific enterprise. It has become the cornerstone for coping with the challenges ahead of mankind. This book reflects and addresses the changes while providing the essential conceptual and analytical tools needed to understand and work in the MCE research field.
Автор: Miguel A. Aon; Valdur Saks; Uwe Schlattner Название: Systems Biology of Metabolic and Signaling Networks ISBN: 3642385044 ISBN-13(EAN): 9783642385049 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Starting with historical roots, this work explores the systems biology of signaling networks, cellular structures and fluxes, organ and microorganism functions. In doing so, it establishes the basis of a 21st century approach to biological complexity.
Автор: Hal S. Alper Название: Systems Metabolic Engineering ISBN: 1493962922 ISBN-13(EAN): 9781493962921 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes the methodologies and approaches in systems metabolic engineering and provides a step-by-step guide for their implementation. Includes readily reproducible laboratory protocols and tips on troubleshooting.
Автор: Xiaoyuan Wang; Jian Chen; Peter Quinn Название: Reprogramming Microbial Metabolic Pathways ISBN: 9400792433 ISBN-13(EAN): 9789400792432 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Metabolic engineering has been developed over the past 20 years to become an important tool for the rational engineering of industrial microorganisms. The overall goal is to achieve a better understanding of the metabolism in different microorganisms, and provide a rational basis to reprogram microorganisms for improved biochemical production.
Автор: Miguel A. Aon; Valdur Saks; Uwe Schlattner Название: Systems Biology of Metabolic and Signaling Networks ISBN: 3662508354 ISBN-13(EAN): 9783662508350 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Starting with historical roots, this work explores the systems biology of signaling networks, cellular structures and fluxes, organ and microorganism functions. In doing so, it establishes the basis of a 21st century approach to biological complexity.
Автор: Thomas O. Metz Название: Metabolic Profiling ISBN: 149395816X ISBN-13(EAN): 9781493958160 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents protocols that are illustrative of the evolution of metabolic profiling from single molecule analysis to global metabolome profiling. It features cutting-edge protocols, presented from the perspective of leading experts in the field.
Автор: Martine Dieuaide-Noubhani; Ana Paula Alonso Название: Plant Metabolic Flux Analysis ISBN: 1493960504 ISBN-13(EAN): 9781493960507 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This new addition to Springer`s popular series Methods in Molecular Biology includes stepwise instructions for reproducing cutting-edge techniques in plant metabolic flux analysis, as well as key notes and practical advice from a host of recognized experts.
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